Abstract: The present invention provides serotonergic benzofurans of Formula (I): where A, R, R1, R2, R3, and R4 are as described in the specification.
Type:
Grant
Filed:
July 21, 2000
Date of Patent:
April 19, 2005
Assignee:
Eli Lilly and Company
Inventors:
Karin Briner, Joseph Paul Burkhart, Timothy Paul Burkholder, Brian Eugene Cunningham, Matthew Joseph Fisher, William Harlan Gritton, Cynthia Darshini Jesudason, Shawn Christopher Miller, Jeffrey Thomas Mullaney, Matthew Robert Reinhard, Roger Ryan Rothhaar, Freddie Craig Stevens, Leonard Larry Winneroski, Yanping Xu, Yao-Chang Xu
Abstract: The present invention relates to a compound of formula I and a process for making:
or a pharmaceutical acid addition salt thereof; which are useful for activating 5-HT1F receptors and inhibiting neuronal protein extravasation in a mammal.
Type:
Grant
Filed:
December 4, 2001
Date of Patent:
August 17, 2004
Assignee:
Eli Lilly and Company
Inventors:
Joseph Herman Krushinski, Jr., Vincent Mancuso, Freddy Andre Napora, John Mehnert Schaus