Patents Represented by Attorney, Agent or Law Firm Robert E. Alderson
  • Rhenium and technetium complexes containing a hypoxia-localizing moiety
    Patent number: 6184361
    Abstract: Novel methods, processes and metal complexes attached to a hypoxia-localizing moiety comprising a metal, preferably radionuclide of rhenium or technetium; a hypoxia-localizing moiety; and, a complexing ligand, wherein said ligand and said radionuclide combined have cell membrane permeabilities greater than that of sucrose, are disclosed.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: February 6, 2001
    Assignee: Bracco International B.V.
    Inventors: Karen Linder, Adrian D. Nunn, David P. Nowotnik, Kondareddiar Ramalingam, Richard J. DiRocco, William L. Rumsey, John P. Pirro