Abstract: The present invention relates to compounds of formula (I): in which X represents N or CH; R1 represents a hydrogen or halogen atom or a CF3 group; n is an integer from 1 to 5; A represents a partially saturated carbonaceous bi- or tricycle; it also relates to their salts, solvates, N-oxides, the pharmaceutical compositions containing them, a method for their preparation and synthesis intermediates in this method.
Type:
Grant
Filed:
October 14, 2002
Date of Patent:
February 5, 2008
Assignee:
Sanofi-Aventis
Inventors:
Marco Baroni, Bernard Bourrie, Rosanna Cardamone, Pierre Casellas
Abstract: The present invention relates to compounds of formula (I): in which X represents N or CH; R1 represents a hydrogen or halogen atom or a CF3 group; R2 and R3 independently represent a hydrogen atom or a methyl group; n is 0 or 1; A represents a condensed heterocyclic group of formula (w) where W completes an aromatic or saturated 6-membered ring system comprising one or two nitrogen atoms or else an aromatic or saturated 5-membered ring system comprising a nitrogen, oxygen or sulfur atom which are optionally substituted, and to their N-oxides and to their salts or solvates, to the pharmaceutical compositions and the medicaments comprising them and to a process for their preparation.
Type:
Grant
Filed:
April 19, 2002
Date of Patent:
February 5, 2008
Assignee:
Sanofi-Aventis
Inventors:
Marco Baroni, Bernard Bourrie, Pierre Casellas