Abstract: The present invention relates to novel pharmaceutical aerosol formulations comprising: (A) a therapeutic agent in the form of particles coated by at least one coating excipient and at least one surfactant, in suspension in (B) a liquefied propellant gas for the administration of therapeutic agents particularly by the pulmonary route and to process for preparing these formulations. It also relates to novel particles suitable for use in such formulations.
Type:
Grant
Filed:
February 11, 2003
Date of Patent:
April 21, 2009
Assignee:
SmithKline Beecham Corporation
Inventors:
Pascal Cavaillon, Nathalie Llorca, Olivier Louis, Patrick Rosier