Abstract: This invention pertains to a process for increasing by at least about 100% the viscosity of a carrageenan-containing dentifrice composition that comprises allowing the composition to quiescently cool from a temperature at or above about 45° C. The process may be applied to making toothpastes having suitable viscosity using carrageenan levels as low as about 0.05 weight percent. The dentifrice compositions are comprised of one or more of the following carrageenans: iota, modified kappa, or mixtures thereof. Toothpastes prepared using this method are easier to process and require much less carrageenan relative to similar viscosity toothpastes prepared by previous methods. This invention also pertains to certain toothpaste compositions having low levels of carrageenan including those made according to this process.

Abstract: Described herein is a toothpaste composition which comprises an orally acceptable vehicle, a polishing agent, a surface active agent and a binder, the binder containing kappa carrageenan and a cellulose gum, the percent by weight concentration of binder being in the range of about 0.30 to 0.80%, and the ratio of kappa carrageenan to cellulose gum being in the range of about 25:75 to 75:25. A preferred concentration of binder is in the range of about 0.45 to 0.65 and a preferred ratio of kappa carrageenan to cellulose gum is in the range of about 55:45 to 75:25. The toothpaste is surprisingly non-stringy, exhibits good consistency, transparency and physical stability.

Abstract: A stable, high moisture toothpaste has now been developed that comprises a carrageenan binder that is at least 70% iota carrageenan, a calcium based-polishing agent, humectant, surfactant, water and optional additives and therapeutic actives used in dentrifice compositions. The calcium-based agent is present at a weight percent concentration in the range of about 35 to 50, the water is about 35 to 50%, the humectant is about 5 to 15%, the carrageenan is about 0.5 to 0.85%, and the surfactant is about 0.5 to 5%. The high moisture, low cost toothpaste that is provided has favorable physical properties such as good viscosity and stability without the need for additional binder which is optional.

Abstract: The present invention provides a method for preparing a spray-dried compressible granular formulation for preparing pharmaceutical tablets in which hydrolyzed cellulose is used as a granulation aid, the resulting granulations, and pharmaceutical tablets compressed from such granules. In these formulations there is employed from 1 to 97% by weight pharmaceutical active, from about 3 to 99% by weight hydrolyzed cellulose, based on the dry weight of the granulation, and optionally conventional granulation and/or tableting additives such as surfactants, disintegrants and antiadherents/flow aids.

Abstract: Novel pharmaceutical suspensions comprising a pharmaceutically active ingredient suspended in aqueous media with a suspending agent comprising attrited microcrystalline cellulose coprocessed and at least partially surface coated with a calcium sodium alginate salt complex barrier dispersant and readily dispersible and hydratable dry formulations thereof are described and exemplified.

Abstract: Particulate pharmaceutical tablet excipient compositions comprising co-processed microcrystalline cellulose and particulate USP calcium carbonate having a particle size distribution of 7 to 22 .mu.m wherein the range of calcium carbonate to microcrystalline cellulose is 70:30 to 90:10.

Abstract: A particulate co-processed unattrited microcrystalline cellulose:hydrocolloid composition wherein the respective components are present in a weight ratio of from about 99:1 to 70:30. The composition is useful as a spheronizing agent for producing spheroids of uniform size and sphericity and having high drug loadings. The composition is produced by drying a slurry of the microcrystalline cellulose in an aqueous solution of the hydrocolloid. The preferred hydrocolloid is methylcellulose.

Abstract: Formulations of chewable pharmaceutical tablets for delivery of prescription pharmaceutical actives, non-prescription pharmaceutical actives, or over-the-counter actives comprise as an excipient an aggregate of coprocessed microcrystalline cellulose and a galaotomannan. Addition of these excipients imparts improved smell, taste, texture, and mouthfeel to the finished product.

Abstract: Phosphonic coletomers of the formula I: ##STR1## wherein X.sub.5 is hydrogen, an alkali metal atom, an alkaline earth metal atom, or an ammonium or amine residue; and A.sub.2 is a copolymer residue comprising two different residues ##STR2## wherein r is an integer ranging from 2 to 100, and wherein, in the first residue, W.sub.3 is --COOH, and in the second residue, W.sub.3 is --CONHC(CH.sub.3).sub.2 CH.sub.2 SO.sub.3 X.sub.5 wherein X.sub.5 is as hereinbefore defined. The cotelomers inhibit scale and corrosion in aqueous systems.

Abstract: A method of treating a population of social insects includes applying topically to the insect a composition comprising a carrier and an active ingredient. The composition provides a coating that adheres to the insect and is groomable and ingestible by other insects to distribute the active ingredient within the population. In accordance with a preferred embodiment, the composition includes sulfluramid as an active ingredient and an air dryable resin as a carrier. A trap for collection of insects controls temperature within the trap to promote recruitment and also drive the insects to a collection area where they may be treated.

Abstract: Compositions for the gel electrophoresis separation of conformational isomers of nucleic acids and agarose compositions useful in such compositions. The compositions use compositions comprising: at least one aqueous gel which is at least one highly derivatized agarose derivatized sufficiently to reduce its gelling temperature (Tg) to below 17.degree. C., present in 40 wt % or more based upon the gel total weight, in admixture with at least one high gel-strength polysaccharide aqueous gel other than polyacrylamide in a balance to 100% total gel weight; and an electrophoretic buffer, present in an electrophoretic buffer--effective amount. The invention compositions comprise at least one aqueous gel comprising at least one agarose derivatized sufficiently to reduce its gelling temperature (Tg) to below 9.degree. C.

Abstract: A method for sanitizing a fowl that has been defeathered and eviscerated by contacting the fowl with peracetic acid solution containing from 100 to 2000 ppm peracetic acid. Completely contacting the fowl with peracetic acid solution effectively reduces the bacterial level found on the fowl to a level that will not produce disease in human beings.

Abstract: The lubricity (anti-wear properties) of hydrocarbon fuels, oxygenate fuels or mixtures thereof, particularly diesel or aviation fuels having reduced sulphur and/or aromatic content for compliance with regulatory requirements, is improved by the addition of a phosphorus ester or esters (phosphates and/or phosphites), or a concentrate containing the ester or esters, having a total acid number at least 1.0 mg KOH/g. The additives also improve corrosion inhibition.

Abstract: A reduced calorie sandwich cookie wherein the weight percent of fat and/or oil of the cookie filler is reduced by at least one quarter and replaced by a predominantly non-caloric bulking agent having a water absorptivity of 200% or less while maintaining the water activity of the entire filler at from 0.2 to 0.7.

Abstract: Substantially dry, rehydratable, water-dispersible, gel-forming, porous hydrocolloid microparticulates containing internally or internally and externally at least one water-soluble, non-gelling, hydration enhancing hydrocolloid, processes and intermediates for their preparation, and their uses.

Abstract: A method of treating a population of social insects includes applying topically to the insect a composition comprising a carrier and an active ingredient. The composition provides a coating that adheres to the insect and is groomable and ingestible by other insects to distribute the active ingredient within the population. In accordance with a preferred embodiment, the composition includes sulfluramid as an active ingredient and an air dryable resin as a carrier. A trap for collection of insects controls temperature within the trap to promote recruitment and also drive the insects to a collection area where they may be treated.

Abstract: A stabilizer composition useful for frozen desserts contains a water soluble hydrocolloid and microcrystalline cellulose coprocessed with an alginate salt complex. The method of using the stabilizer composition provides good resistance to heat shock in frozen desserts. The frozen desserts containing the stabilizer system, including such products with less than five percent fat, exhibit resistance to heat shock and good textural characteristics.

Abstract: Phosphonic telomer intermediates for preparing the telomers of U.S. Pat. No. 5,376,731 may be produced by an aqueous process comprising (a) reacting hypophosphorous acid with a carbonyl compound which is preferably an aldehyde, a ketone or an imine, and (b) reacting the product of (a) with an olefinic reactant or reactants in the presence of a suitable initiator especially a free radical initiator. The telomer intermediates are themselves useful as scale inhibitors in aqueous systems.

Abstract: A process for the preparation of hydrocarbon solutions of monofunctional ether initiators of the following general structure:M--Z--O--C(R.sup.1 R.sup.2 R.sup.3)wherein M is an alkali metal; Z is a branched or straight chain hydrocarbon group which contains 3-25 carbon atoms, optionally containing aryl or substituted aryl groups; and R.sup.1, R.sup.2, and R.sup.3 are independently selected from hydrogen, alkyl, substituted alkyl, aryl or substituted aryl groups, and their employment as initiators in the anionic polymerization of olefin containing monomers in an inert, hydrocarbon solvent comprising reacting an omega-protected-1-haloalkyl with lithium metal dispersion having a particle size between 10 and 300 millimicrons in size, at a temperature between 35.degree. and 130.degree. C. in an alkane solvent containing 5 to 10 carbon atoms.

Abstract: The invention provides an aqueous colloidal peroxygen composition comprising stable sols, gels and solids of C2 to C6 peroxycarboxylic acids with a polysaccharide gum, optionally with gum cross-linking agents such as boric acid, borate salts, urea and the like useful for delivering peracids in applications such as surface cleaners, detergent bleach, automatic dish washing formulations and the like. The compositions are particularly useful for sanitizing or bleaching at an acid or neutral pH compared with other chlorine or peroxygen bleach compounds.