Abstract: A method of, and oral composition for, inhibiting adherence of Streptococcus pyogenes to pharyngeal and oral mucosa cells by treating these cells with an oligosaccharide having at least one fucose moiety or a galactose moiety which is free of digalactose and N-acetylneuraminyl lactose.
Type:
Grant
Filed:
January 11, 1991
Date of Patent:
March 10, 1992
Assignees:
Colgate-Palmolive, Forsyth Dental Center
Inventors:
Abdul Gaffar, Ronald J. Gibbons, Stanislawa Tylewska
Abstract: A buccal lozenge medication for providing fluoride ion for the prevention and treatment of bone loss disease. The dosage is a lozenge containing from 20 to 100 milligrams of sodium monofluorophosphate and further including a slow release mechanism for controlling release of the fluoride ion while in the mouth. Up to ten percent of sodium fluoride can be added.
Abstract: A method of, and oral composition for, inhibiting adherence of Streptococcus pyogenes to pharyngeal and oral mucosa cells by treating these cells with an oligosaccharide having at least one fucose moiety or a galactose moiety which is free of digalactose and N-acetylneuraminyl lactose.
Type:
Grant
Filed:
July 25, 1989
Date of Patent:
March 26, 1991
Assignees:
Colgate-Palmolive Company, Forsyth Dental Center
Inventors:
Abdul Gaffar, Ronald J. Gibbons, Stanislawa Tylewksa