Abstract: A cable protecting tube having high transparency and allowing the filling condition of mortar therein to be visually observed from the outside as well as exhibiting high pressure resistance is provided.
A cable protecting tube for accommodating a cable and for filling with mortar includes a protecting tube (1) having smooth inner and outer surfaces formed from an ionomer resin excellent in transparency, and a spiral or mesh-shaped reinforcing member (2) for reinforcing the protecting tube. The reinforcing member (2) may be buried in the protecting tube (1). The protecting tube (1) is not limited to the smooth-walled tube but may be a spirally corrugated tube.
Type:
Grant
Filed:
June 9, 2003
Date of Patent:
October 19, 2004
Assignees:
Anderson Technology Corporation, Shinko Wire Company, Tigers Polymer Corporation
Abstract: 1-(3-methoxybenzyl)-3-substituted thiourea antioxidant compounds and improved lipids compositions which are supplemented with amounts of such antioxidant compounds effective for augmenting oxidative stability of the base lipid are provided. Also provided are methods for enhancing the oxidative stability of a lipid comprising supplementing a base lipid in need of enhanced oxidative stability with at least one 1-(3-methoxybenzyl)-3-substituted thiourea compound of the present invention.
Type:
Grant
Filed:
April 23, 2001
Date of Patent:
November 25, 2003
Assignees:
The United States of America as represented by the Secretary
of Agriculture, The Fanning Corporation
Abstract: 1-(3-methoxybenzyl)-3-substituted thiourea antioxidant compounds and improved lipids compositions which are supplemented with amounts of such antioxidant compounds effective for augmenting oxidative stability of the base lipid are provided. Also provided are methods for enhancing the oxidative stability of a lipid comprising supplementing a base lipid in need of enhanced oxidative stability with at least one 1-(3-methoxybenzyl)-3-substituted thiourea compound of the present invention.
Type:
Grant
Filed:
February 14, 2002
Date of Patent:
July 1, 2003
Assignees:
The United States of America, as represented by the Secretary
of Agriculture, The Fanning Corporation
Abstract: The present invention provides food bars for consumption by pregnant women, lactating women or women of childbearing potential that are attempting to become pregnant containing one or more vitamins and/or minerals, DHA, one or more DHA taste-masking agents and, optionally, one or more anti-constipation and regularity-maintaining agents, methods for preparing these food bars, and methods for supplementing the dietary requirements of pregnant women, lactating women or women of childbearing potential that are attempting to become pregnant.
Type:
Grant
Filed:
February 19, 2002
Date of Patent:
June 10, 2003
Assignee:
PBM Pharmaceuticals, Inc.
Inventors:
Paul B. Manning, Jack H. Schramm, James W. McGrath, Jr.
Abstract: The present invention provides food bars for consumption by pregnant women, lactating women or women of childbearing potential that are attempting to become pregnant containing one or more vitamins and/or minerals, and one or more anti-constipation and regularity-maintaining agents, methods for preparing these food bars, and methods for supplementing the dietary requirements of pregnant women, lactating women or women of childbearing potential that are attempting to become pregnant.
Type:
Grant
Filed:
December 5, 2000
Date of Patent:
May 27, 2003
Assignee:
PBM Pharmaceuticals, Inc.
Inventors:
Paul B. Manning, Jack H. Schramm, James W. McGrath, Jr.
Abstract: A method is provided for inhibiting free radical degradation in the skin of a human or nonhuman animal comprising contacting the skin with a skin treatment composition having a concentration of a 1-(3-methoxybenzyl)-3-substituted thiourea compound effective for inhibiting free radical generation. Skin protecting compositions comprising a free radical inhibiting concentration of a 1-(3-methoxybenzyl)-3-substituted thiourea compound, and optionally a sunscreeen composition, are also provided.
Abstract: The present invention provides a method for preventing or reducing a photosensitivity and/or phototoxicity reaction which may be caused by a once-per-day dose of a medication which causes a photosensitivity and/or phototoxicity reaction in a patient comprising administering the prescribed or suggested dose of the medication to the patient during the evening or early morning hours.
Type:
Grant
Filed:
January 28, 1994
Date of Patent:
September 16, 1997
Assignee:
G. D. Searle & Co.
Inventors:
Paul Dale Klimstra, Barbara Roniker, Edward Allen Swabb
Abstract: The present invention provides substituted dibenzoxazepine compounds of Formula I: ##STR1## which are useful as analgesic agents for the treatment of pain, and for the treatment of prostaglandin E.sub.2 -mediated diseases, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, a method for eliminating or ameliorating pain in an animal, and a method for treating prostaglandin E.sub.2 -mediated diseases in an animal, comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.
Type:
Grant
Filed:
March 10, 1995
Date of Patent:
April 30, 1996
Assignee:
G. D. Searle & Co.
Inventors:
Nizal S. Chandrakumar, Horng-Chih Huang, Richard A. Mueller
Abstract: The present invention provides substituted dibenzoxazepine and dibenzthiazepine compounds of Formula I: ##STR1## which are useful as analgesic agents for the treatment of pain, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, and a method for eliminating or ameliorating pain in an animal comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.
Type:
Grant
Filed:
February 22, 1995
Date of Patent:
April 2, 1996
Assignee:
G. D. Searle & Co.
Inventors:
Joe T. Collins, Donald W. Hansen, Jr., Karen H. Peterson, Barnett S. Pitzele, David B. Reitz
Abstract: The present invention provides substituted dibenzoxazepine compounds of Formula I: ##STR1## which are useful as analgesic agents for the treatment of pain, and as prostaglandin-E.sub.2 antagonists for the treatment of prostaglandin-E.sub.2 mediated diseases, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, a method for eliminating or ameliorating pain in an animal, and a method for treating prostaglandin-E.sub.2 mediated diseases in an animal, comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.
Type:
Grant
Filed:
November 3, 1993
Date of Patent:
January 30, 1996
Assignee:
G. D. Searle & Co.
Inventors:
Robert A. Chrusciel, Timothy J. Hagen, E. Ann Hallinan, Jinglin Li, Sofya Tsymbalov, David B. Reitz
Abstract: The present invention relates to derivatives of cyclic phenolic thioethers of the formula: ##STR1## and the pharmaceutically acceptable salts thereof, which are inhibitors or stimulators of superoxide generation, and which may also inhibit cyclooxygenase and/or 5-lipoxygenase, to pharmaceutical compositions containing one or more of these compounds in combination with a pharmaceutically-acceptable carrier, and to medical methods of treatment employing these compounds.
Type:
Grant
Filed:
May 19, 1994
Date of Patent:
December 19, 1995
Assignee:
G. D. Searle & Co.
Inventors:
Richard A. Partis, Richard A. Mueller, Francis J. Koszyk, Richard M. Weier
Abstract: The present invention provides dibenzoxazepine compounds, of Formula I: ##STR1## which are useful as analgesic agents for the treatment of pain, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, and a method for eliminating or ameliorating pain in an animal comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.
Type:
Grant
Filed:
August 24, 1994
Date of Patent:
November 7, 1995
Assignee:
G. D. Searle & Co.
Inventors:
E. Ann Hallinan, Timothy J. Hagen, Robert K. Husa, Sofya Tsymbalov, Albert C. Lee, Jean-Pierre Van Hoeck
Abstract: The present invention provides substituted dibenzoxazepine and dibenzthiazepine compounds of Formula I: ##STR1## which are useful as analgesic agents for the treatment of pain, and for prostaglandin-E.sub.2 mediated diseases, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, a method for eliminating or ameliorating pain in an animal comprising administering a therapeutically-effective amount of a compound of Formula I to the animal, and a method for treating prostaglandin-E.sub.2 mediated diseases in an animal comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.
Type:
Grant
Filed:
May 18, 1994
Date of Patent:
October 24, 1995
Assignee:
G. D. Searle & Co.
Inventors:
Donald W. Hansen, Jr., Karen B. Peterson
Abstract: The present invention provides substituted dibenzoxazepine compounds of Formula I: ##STR1## which are useful as analgesic agents for the treatment of pain, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, and a method for eliminating or ameliorating pain in an animal comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.
Type:
Grant
Filed:
September 24, 1993
Date of Patent:
October 24, 1995
Assignee:
G. D. Searle & Co.
Inventors:
Robert K. Husa, Michael F. Rafferty, Timothy J. Hagen, E. Ann Hallinan
Abstract: The present invention provides substituted dibenzoxazepine and dibenzthiazepine compounds of Formula I: ##STR1## which are useful as analgesic agents for the treatment of pain, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, and a method for eliminating or ameliorating pain in an animal comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.
Type:
Grant
Filed:
June 9, 1994
Date of Patent:
September 12, 1995
Assignee:
G. D. Searle & Co.
Inventors:
Nizal S. Chandrakumar, Donald W. Hansen, Jr., Karen B. Peterson, Barnett S. Pitzele
Abstract: The present invention provides substituted dibenzoxazepine compounds of Formula I: ##STR1## which are useful as analgesic agents for the treatment of pain, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, and a method for eliminating or ameliorating pain in an animal comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.
Type:
Grant
Filed:
January 10, 1994
Date of Patent:
September 12, 1995
Assignee:
G. D. Searle & Co.
Inventors:
Nizal S. Chandrakumar, Timothy J. Hagen, E. Ann Hallinan, Robert K. Husa
Abstract: The present invention provides substituted dibenzoxazepine and dibenzthiazepine compounds of Formula I: ##STR1## which are useful as analgesic agents for the treatment of pain, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, and a method for eliminating or ameliorating pain in an animal comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.
Type:
Grant
Filed:
June 9, 1994
Date of Patent:
August 15, 1995
Assignee:
G. D. Searle & Co.
Inventors:
Joe T. Collins, Donald W. Hansen, Jr., Karen B. Peterson, Barnett S. Pitzele, David B. Reitz
Abstract: The present invention provides novel substituted opioid analgesic compounds of Formula I: ##STR1## which are opioid agonists, and which are useful as analgesic agents for the treatment of pain, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, and a method for eliminating or ameliorating pain in an animal comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.
Type:
Grant
Filed:
May 16, 1994
Date of Patent:
July 25, 1995
Assignee:
G. D. Searle & Co.
Inventors:
Michael S. Dappen, Barnett S. Pitzele, Michael F. Rafferty
Abstract: The present invention provides substituted dibenzoxazepine compounds of Formula I: ##STR1## which are useful as analgesic agents for the treatment of pain, and as prostaglandin-E.sub.2 antagonists for the treatment of prostaglandin-E.sub.2 mediated diseases, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, a method for eliminating or ameliorating pain in an animal, and a method for treating prostaglandin-E.sub.2 mediated diseases in an animal, comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.
Type:
Grant
Filed:
October 7, 1993
Date of Patent:
June 13, 1995
Assignee:
G. D. Searle & Co.
Inventors:
Nizal S. Chandrakumar, Richard A. Mueller
Abstract: The present invention provides compounds of the formula: ##STR1## and the pharmaceutically acceptable salts thereof, wherein: R.sup.1 and R.sup.2 are each alkyl;n is an integer of from 1 to 4;x is oxygen or --(CH.sub.2).sub.m --;m is an integer of from 1 to 3;y is oxygen or sulfur; andp is an integer of from 1 to 4.These compounds are inhibitors of COX-I and/or COX-II, and are useful for the treatment of inflammation-associated disorders.The present invention also provides pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, and a method for treating inflammation-associated disorders in an animal comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.