Abstract: This invention relates to compounds of Formula I and the use of compounds of Formula I as neuroprotective agents in the treatment of neuronal disorders of the central and peripheral nervous systems.
Type:
Grant
Filed:
May 7, 2007
Date of Patent:
May 11, 2010
Assignee:
Aegera Therapeutics Inc.
Inventors:
James B. Jaquith, Alain Boudreault, Stephen J. Morris, Jon Durkin, John W. Gillard, Kimberley E. Hewitt
Abstract: The present invention relates to HCV variants, particularly variants that are resistant to a protease inhibitors such as VX-950. Also provided are methods and compositions related to the HCV variants. Further provided are methods of isolating, identifying, and characterizing multiple viral variants from a patient.
Type:
Grant
Filed:
November 13, 2006
Date of Patent:
April 27, 2010
Assignee:
Vertex Pharmaceuticals Incorporated
Inventors:
Chao Lin, Tara Kieffer, Christoph Sarrazin, Ann Kwong