Patents Represented by Attorney Ronald I. Dike, Bronstein, Roberts & Cushman Eisenstein

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  • Immunogenic peptides, antibodies and uses thereof relating to CD4 receptor binding
    Patent number: 5817316
    Abstract: Immunogenic peptides containing amino acid residues which define a binding site to a CD4 receptor are disclosed. Antibodies to these peptides are also disclosed. Methods of reducing the ability of a gp120 env protein to bind to CD4 are also disclosed. Methods of treatment and prophylaxis using these antibodies and peptides are also described.
    Type: Grant
    Filed: March 26, 1992
    Date of Patent: October 6, 1998
    Assignee: Dana-Farber Cancer Instistute
    Inventors: Joseph G. Sodroski, William A. Haseltine, Craig D. Furman, Udy Olshevsky, Eirik Helseth, Richard Wyatt, Markus Thali