Abstract: A vacuum deposition method for fabricating high-strength nitinol films by sputter depositing nickel and titanium from a heated sputtering target, and controlling the sputter deposition process parameters in order to create high-strength nitinol films that exhibit shape memory and/or superelastic properties without the need for precipitation annealing to attenuate the transition conditions of the deposited material. A vacuum deposited nitinol film having high-strength properties equal to or better than wrought nitinol films and which are characterized by having non-columnar crystal grain structures.
Type:
Grant
Filed:
October 19, 2007
Date of Patent:
December 27, 2011
Assignee:
Advanced Bio Prosthetic Surfaces, Ltd.
Inventors:
Denes Marton, Christopher T. Boyle, Roger W. Wiseman, Christopher E. Banas
Abstract: The invention relates to methods and apparatus for manufacturing intravascular stents wherein the intravascular stent has its inner surface treated to promote the migration of endothelial cells onto the inner surface of the intravascular stent. In particular, the inner surface of the intravascular stent has at least one groove formed therein.
Type:
Grant
Filed:
May 18, 2001
Date of Patent:
October 18, 2011
Assignee:
Advanced Bio Prosthetic Surfaces, Ltd.
Inventors:
Christopher E. Banas, Julio C. Palmaz, Eugene A. Sprague
Abstract: A novel contrast mechanism for imaging blood flow using magneto-motive optical Doppler tomography (MM-ODT), Optical Coherence Tomography, and Ultrasound. MM-ODT, OCT, and ultrasound combined with an externally applied temporally oscillating high-strength magnetic field detects erythrocytes moving according to the field gradient.
Type:
Grant
Filed:
October 18, 2006
Date of Patent:
October 11, 2011
Assignee:
Board of Regents, The University of Texas System
Abstract: An endoluminal stent composed of a plurality of circumferential expansion elements arrayed to form the circumference of the stent and extending along the longitudinal axis of the stent, and a plurality of interconnecting members that interconnect adjacent pairs of circumferential expansion elements, the interconnecting members joining struts of adjacent pairs of interconnecting members at approximate mid-points of the struts.
Type:
Grant
Filed:
October 13, 2006
Date of Patent:
July 19, 2011
Assignee:
Advanced Bio Prosthetic Surfaces, Ltd.
Inventors:
Christopher E. Banas, David G. Rosenbaum
Abstract: Provided herein are systems and methods for the detection of cells and/or compositions using optical coherence tomography. The systems and methods comprise a plurality of magnets for applying a plurality of distinct magnetic field strengths to the cells and/or compositions and a phase sensitive optical coherence tomographic imaging modality for detecting the cells and/or compositions while same are disposed in the presence of at least one of the plurality of distinct magnetic field strengths.
Type:
Grant
Filed:
May 26, 2006
Date of Patent:
July 19, 2011
Assignee:
Board of Regents, The University of Texas Systems
Inventors:
Marc D. Feldman, Thomas E. Milner, Jung-Hwan Oh, Mehmet Cilingiroglu
Abstract: Disclosed are improved methods and compositions for use in light-based in vivo imaging and treatment. The techniques described involve the use of low-scattering, oxygen-carrying blood substitutes in imaging and treatment methods, including OCT imaging. The invention has particular advantages in imaging within the cardiovascular system and highly vascularized or oxygen-dependent tissues.
Type:
Grant
Filed:
May 14, 2010
Date of Patent:
July 19, 2011
Assignee:
Board of Regents, The University of Texas System
Inventors:
Joseph W. Villard, Thomas E. Milner, Marc D. Feldman, Jeehoon Kim, Gregory L. Freeman
Abstract: Provided herein are systems, methods, and compositions for optical coherence tomography implementations. The OCT implementation generally applies to both spectrometer-based and swept source-based implementations of PS-FD-OCT, and also to both fiber based and bulk-optical and Michelson and Mach-Zender PS-OCT implementations, where the detection arm is free from two photoreceivers or spectrometers for detecting the interference of the first polarization state and the second polarization state.
Abstract: A grippable sports device in the form of a band is configured for use as a lifting aid and comprises a main body for placing in a position on the limb of a sports player for use during a sports game, the main body comprising fixing means for fixing the main body in a substantially fixed position directly on the player's limb, with the main body further including a non-slip surface configured to enable a second player of the sports game to firmly grip the main body. When the sports band is in a fixed position on a wearer, the fixing means substantially encircles a portion of the wearer's limb. The grippable sports band is particularly useful in a line-out in the game of Rubgy Union.
Abstract: The present invention relates to a rotating catheter tip for optical coherence tomography based on the use of an optical fiber that does not rotate, that is enclosed in a catheter, which has a tip rotates under the influence of a fluid drive system to redirect light from the fiber to a surrounding vessel and the light reflected or backscattered from the vessel back to the optical fiber.
Type:
Grant
Filed:
October 20, 2006
Date of Patent:
December 14, 2010
Assignees:
Board of Regents, the University of Texas System, Volcano Corporation
Inventors:
Thomas E. Milner, Marc D. Feldman, Jung-Hwan Oh, Shaochen Chen, Paul Castella
Abstract: The invention is a rotating tip catheter-imaging probe where electromagnetic energy is delivered to the distal end of a catheter and converted to mechanical energy using a light drive apparatus. The mechanical energy is then used to rotate a mirror that redirects light in fixed pattern on a sample. The rotating element of the light drive apparatus contains vanes, which rotate about an axis and positioned with bearings to minimize friction. A chamber encompasses the rotating element and is set to a vacuum pressure. The rotational speed of the catheter tip can be controlled by varying the optical power delivered to the vanes, the vacuum pressure in the chamber, or by a braking mechanism applied to the rotating element. The vanes may be shaped in a particular geometry to increase forces on the vanes from thermally driven gas flow.
Type:
Grant
Filed:
December 6, 2006
Date of Patent:
November 30, 2010
Assignee:
Board of Regents, the University of Texas System
Abstract: The present invention relates to an air filtration system and a method for making a photocatalytic oxidation substrate by powder coating a photocatalyst onto a metal substrate.
Abstract: A lightweight multilayer heat reflective concrete cure blanket having a moisture-impervious top outer layer, a moisture-impervious bottom outer layer, and the top and bottom layers sealingly connected to each other at the boundaries of the layers to form a moisture-impervious chamber between the first and second layers. The chamber includes at least one bubble type insulative layer therein, and the bottom surface of the blanket comprises a heat reflective material to reflect heat emanating from the concrete when the blanket is placed over the concrete. In a further embodiment, heat reflective material is applied to at least one inner bubble type layer to reflect additional heat which radiates from the concrete through the insulative layer and back towards the concrete.
Abstract: Provided herein are systems, methods and compositions for the use of optical coherence tomography for detection of cells and for killing detected cells. A detected cell can be killed or injured by contacting a composition comprised by the cell with energy. Energy can be applied to a particle comprised by the cell.
Type:
Grant
Filed:
April 6, 2007
Date of Patent:
September 21, 2010
Assignee:
Board of Regents, the University of Texas System
Inventors:
Marc D. Feldman, Thomas E. Milner, Jihoon Kim, Junghwan Oh, Pramod Sanghi, Jake Mancuso, Keith P. Johnston, Leo Ma, Stas Emelianov
Abstract: This invention relates to prosthetic cardiac and venous valves and a single catheter device and minimally invasive techniques for percutaneous and transluminal valvuloplasty and prosthetic valve implantation.
Abstract: A bioactive complex composition having enhanced oxidative stability, emulsion stability, mineral rich transparent beverages and a wide range of functional health benefits. The composition may include as a base composition individual ingredients or a synergistic blend of mineral salts, Omega-3 rich oils, phospholipids, chitosan, and alpha-casein, beta-casein, kappa-casein or protein fragments, glycopeptides, phosphopeptides. The composition may optionally be further utilized for the prevention of hypercholesterolemia, bone (and teeth) mineral loss, treatment of mental health diseases, heart health, additional nutritional supplementation, and treatment of additional medical conditions.
Abstract: An apparatus is disclosed for studying an object based on at least one of polarization, space, position or angle of light that has reflected from the object. An optical tomographic instrumentation of the apparatus includes a light source coupled to a source path, a sample path, a reference path, and a detection path, wherein the light source generates a spectrally resolved bandwidth. The spectrally resolved bandwidth includes a plurality of spectrally resolved cells and a detector in the detection path for analyzing light reflected from an object in the sample path and the light reflected in the reference path based upon at least one of the polarization, spatial relationship, position or angle domains.
Type:
Grant
Filed:
June 5, 2006
Date of Patent:
August 24, 2010
Assignee:
Board of Regents, The University of Texas System
Inventors:
Marc D. Feldman, Thomas E. Milner, Jung Hwan Oh, Eunha Kim, Karthik Kumar, Chris Condit, Robert Grant, Nate Kemp, Jeehyun Kim, Shaochen Chen, Li-Hsin Han
Abstract: Disclosed are improved methods and compositions for use in light-based in vivo imaging and treatment. The techniques described involve the use of low-scattering, oxygen-carrying blood substitutes in imaging and treatment methods, including OCT imaging. The invention has particular advantages in imaging within the cardiovascular system and highly vascularized or oxygen-dependent tissues.
Type:
Grant
Filed:
January 15, 2003
Date of Patent:
June 29, 2010
Assignee:
Board of Regents, the University of Texas System
Inventors:
Joseph W. Villard, Marc D. Feldman, Thomas E. Milner, JeeHyun Kim, Gregory L. Freeman