Patents Represented by Attorney Roy D. Meredith

Find this attorney in the Justia Lawyer Directory

  • Benzodiazepine analogs
    Patent number: 4820834
    Abstract: Benzodiazepine analogs of the formula: ##STR1## are disclosed which are antagonists of gastrin and cholecystokinin (CCK).
    Type: Grant
    Filed: March 16, 1987
    Date of Patent: April 11, 1989
    Assignee: Merck & Co., Inc.
    Inventors: Ben E. Evans, Roger M. Freidinger, Mark G. Bock
  • Carbamates of 4-hydroxyanisole as prodrugs for chemotherapy of melanoma
    Patent number: 4812590
    Abstract: Derivatives of 4-hydroxyanisole carbamate are suitable as prodrugs for the delivery and concentration of 4-hydroxyanisole in melanomas.
    Type: Grant
    Filed: June 25, 1987
    Date of Patent: March 14, 1989
    Assignee: Merck & Co., Inc.
    Inventor: Walfred S. Saari
  • Esters of 2-(substituted sulfamyl)-6-nitro-benzoic acid and pharmaceutical compositions
    Patent number: 4654369
    Abstract: Amides and esters of 2-(substituted sulfamyl)-6-nitro-benzoic acid, in which the substituents on the sulfamyl nitrogen are non-basic, such as: hydrogen, alkyl, hydroxyalkyl and non-basic heterocycles, which are useful as adjuncts to radiation therapy.
    Type: Grant
    Filed: November 6, 1985
    Date of Patent: March 31, 1987
    Assignee: Merck & Co., Inc.
    Inventor: Walfred S. Saari
  • 2-(substituted sulfamyl)-6-nitrobenzoic acid amides and pharmaceutical compositions
    Patent number: 4647588
    Abstract: 2-(Substituted sulfamyl) derivatives of 6-nitrobenzoic acid wherein at least one of the sulfamyl substituents is a basic substituent selected from amino-(lower alkyl), (lower alkyl)-amino-(lower alkyl), or di(lower alkyl)-amino-(lower alkyl) are disclosed to have activity in increasing the sensitivity of hypoxic tumor cells to therapeutic radiation. Also disclosed are methods of preparing such compounds and pharmaceutical compositions including such compounds.
    Type: Grant
    Filed: November 6, 1985
    Date of Patent: March 3, 1987
    Assignee: Merck & Co., Inc.
    Inventors: Edward L. Engelhardt, Walfred S. Saari
  • Method of inserting unique DNA sequences into DNA vectors
    Patent number: 4528266
    Abstract: Autonomously replicating DNA containing a unique nucleotide sequence, being an oligonucleotide of which its sequence does not otherwise exist in said DNA[inserted in a non-essential region thereof at a site not previously susceptible of restriction endonuclease cleavage].
    Type: Grant
    Filed: September 30, 1982
    Date of Patent: July 9, 1985
    Inventor: George Pieczenik