Abstract: The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising T cells, B cells and antigen-primed dendritic cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals.
Type:
Grant
Filed:
February 17, 2010
Date of Patent:
December 20, 2011
Assignee:
Sanofi Pasteur Vaxdesign Corp.
Inventors:
William L. Warren, Donald Drake, III, Janice Moser, Inderpal Singh, Haifeng Song, Eric Mishkin
Abstract: A device and method are disclosed for processing a data resource changing event in a mobile terminal by recommending a change from a specific, currently used data resource to a new data resource when the data resource has not been changed for a long time. The method for processing a data resource changing event in a mobile terminal comprises storing the data resource changing event occurring in the mobile terminal, confirming a specialist previously set to process the data resource changing event, calling the confirmed specialist to process the data resource changing event, and displaying an avatar and text according to event processing results.
Type:
Grant
Filed:
February 21, 2006
Date of Patent:
December 20, 2011
Assignee:
Samsung Electronics Co., Ltd.
Inventors:
Jae-Ho Kim, Hyun-Ji Kim, Jeong-Wook Seo
Abstract: A development roller for electrophotographic device and a method of making the development roller are disclosed. The development roller according to the present invention includes a central shaft and a roller body. The roller body is composed of an elastic polymer material as a primary material and carbon nanotubes in an amount to provide the conductivity of the roller body. According to the present invention, the development roller can exhibit a low hardness and a low resistance at the same time, produce images having high sharpness, and does not contaminate images.
Abstract: A disposable casket is made from a one piece unitary blank of a foldable sheet material. The blank is folded to form the disposable casket having a bottom wall, opposite side walls and opposite end walls. Each side wall has a top panel that folds inwardly where the outer edges overlap and interlock with each other. Each end wall has a side flap that is superimposed on a respective side wall. A top end panel is connected to each end wall by a fold line which folds over the respective end of the top panels and interlocks with the top panels to retain the top panels and top end panels in a closed position.
Abstract: The present invention relates generally to a Plasmid Maintenance System for the stabilization of expression plasmids encoding foreign antigens, and methods for making and using the Plasmid Maintenance System. The invention optimizes the maintenance of expression plasmids at two independent levels by: (1) removing sole dependence on balanced lethal maintenance functions; and (2) incorporating at least one plasmid partition function to prevent random segregation of expression plasmids, thereby enhancing their inheritance and stability. The Plasmid Maintenance System may be employed within a plasmid which has been recombinantly engineered to express a variety of expression products.
Type:
Grant
Filed:
October 4, 2006
Date of Patent:
December 13, 2011
Assignee:
University of Maryland, Baltimore
Inventors:
James E. Galen, Christofer Vindurampulle
Abstract: A head driving device, an inkjet printer comprising the same and data processing method of an ink jet printer are provided, in which a nozzle driving unit turns on/off a plurality of thermal elements that correspond to a plurality of nozzles and heat ink discharged from the nozzles, a data processing unit processes printing data and outputs a nozzle select signal corresponding to an image to the nozzle driving unit; and a head logic unit receives the printing data externally, divides the printing data of one address group into a plurality of data groups, transmits the plurality of data groups to the data processing unit via different data buses corresponding to the plurality of data groups, respectively, and controls the data processing unit to process the divided printing data. Accordingly, an EMI characteristic between signals can be improved by lowering the data buses density in one area, and a data processing speed can be adjusted by dividedly processing printing data.
Abstract: A vacuum bag includes a container portion having at least one opening. A threaded fitting is disposed in communication with the at least one opening, and the threaded fitting is configured for attachment to a vacuum nozzle of a vacuum cleaner.
Abstract: A method and apparatus for transmitting a broadcast physical layer packet in a mobile communication system supporting multi-slot transmission and hybrid Automatic Repeat Request (H-ARQ) are provided. The method comprises initially transmitting the broadcast physical layer packet according to a fixed transmission format for at least one first slot interval and retransmitting the broadcast physical layer packet for at least one second slot interval using a variable transmission format different from the transmission format used in the first slot interval.
Type:
Grant
Filed:
May 13, 2010
Date of Patent:
December 13, 2011
Assignee:
Samsung Electronics Co., Ltd.
Inventors:
Yu-Chul Kim, Hwan-Joon Kwon, Dong-Hee Kim, Youn-Sun Kim, Jin-Kyu Han
Abstract: The present invention provides cyclic hexadepsipeptides and their pharmaceutically acceptable salts, solvates and prodrugs, and methods for obtaining the compounds, by fermentation, optionally followed by post-biosynthesis chemical modification. The present invention further provides uses of cyclic hexadepsipeptides, and their pharmaceutically acceptable salts, solvates and prodrugs as pharmaceuticals, in particular to their use as antibacterial, antifungal or antineoplastic agents, and to pharmaceutical compositions comprising a cyclic hexadepsipeptide, or a pharmaceutically acceptable salt, solvate or prodrug thereof, together with a carrier.
Type:
Grant
Filed:
March 28, 2007
Date of Patent:
December 13, 2011
Assignee:
Thallion Pharmaceuticals Inc.
Inventors:
Emmanuel Zazopoulos, James B. McAlpine, Arjun H. Banskota, Mahmood Piraee
Abstract: A molded article such as a floor tile is made from recycled carpet waste which includes a polyvinyl chloride component in the backing material and fiber component having a melting point above the melting point of polyvinyl chloride. A mixture of the recycled carpet material is shredded and additional polyvinyl chloride is fed to an extruder where the polyvinyl chloride is melted without melting the carpet fibers. The resulting mixture is discharged and molded, such as by injection molding, to form a molded product. The molded product includes a continuous matrix of polyvinyl chloride having recycled carpet fibers uniformly dispersed therein. The molded article contains about 45% to about 85% of polyvinyl chloride, about 5% to about 20% of recycled carpet fibers, up to about 5% of a plasticizer and up to about 5% of an ethylene copolymer by weight based on the total weight of the product.
Type:
Grant
Filed:
April 2, 2004
Date of Patent:
December 13, 2011
Assignee:
Selectech, Inc.
Inventors:
Thomas E. Ricciardelli, Michael H. King, Michael P. Slater, Steven F. Raposo
Abstract: A terminal device having a correction function for natural color and a method thereof are provided for creating an image closest in color to the natural color. A priority storing unit stores at a reference color data area a range of natural colors which are colors of objects existing in the natural world. A color editing unit corrects natural color image data corresponding to the natural color area, based on a command for correcting the natural area existing in a predetermined image from the user. A controlling unit decides whether the natural color image data corrected by the color editing unit is included in the reference color data area.
Type:
Grant
Filed:
March 6, 2006
Date of Patent:
December 13, 2011
Assignee:
Samsung Electronics Co., Ltd.
Inventors:
Mi-jung Jang, Kyeong-man Kim, Hyun-soo Oh
Abstract: An integrated digital device and a displaying method are provided. The integrated digital device includes a display unit displaying a plurality of setup information items. A plurality of input keys positioned in the vicinity of the plurality of setup information items, respectively, are displayed on the display unit. A mode input unit selecting one among a plurality of modes in which different digital device functions are performed and a modifier modifying at least one of the setup information items according to at least one among the mode selected by the mode input unit and an input from at least one of the input keys.
Type:
Grant
Filed:
July 18, 2006
Date of Patent:
December 6, 2011
Assignee:
Samsung Electronics Co., Ltd.
Inventors:
Hong-seok Yang, Yong-hyun Lee, Ji-hyun Lee
Abstract: The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising T cells, B cells and antigen-primed dendritic cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals.
Type:
Grant
Filed:
June 15, 2006
Date of Patent:
December 6, 2011
Assignees:
Sanofi Pasteur Vaxdesign Corp., Virginia Commonwealth University
Inventors:
William L. Warren, Donald Drake, III, Janice Moser, Inderpal Singh, Haifeng Song, Eric Mishkin, John G. Tew
Abstract: Disclosed is an ophthalmic composition for a soft contact lens, which is characterized in that the adsorption of a terpenoid contained in the composition onto a soft contact lens is reduced. The ophthalmic composition comprises a combination of Component (A) 0.005 to 0.01 wt % of a terpenoid and Component (B) alginic acid and/or a salt thereof.
Abstract: A single chain, polypeptide fusion protein, comprising: a non-cytotoxic protease, or a fragment thereof, which protease or protease fragment is capable of cleaving a protein of the exocytic fusion apparatus of a nociceptive sensory afferent; a Targeting Moiety that is capable of binding to a Binding Site on the nociceptive sensory afferent, which Binding Site is capable of undergoing endocytosis to be incorporated into an endosome within the nociceptive sensory afferent; a protease cleavage site at which site the fusion protein is cleavable by a protease, wherein the protease cleavage site is located between the non-cytotoxic protease or fragment thereof and the Targeting Moiety; and a translocation domain that is capable of translocating the protease or protease fragment from within an endosome, across the endosomal membrane and into the cytosol of the nociceptive sensory afferent. Nucleic acid sequences encoding the polypeptide fusion proteins, methods of preparing same and uses thereof are also described.
Type:
Grant
Filed:
December 1, 2005
Date of Patent:
November 29, 2011
Assignees:
Syntaxin Ltd., Allergan Inc.
Inventors:
Keith Foster, John Chaddock, Philip Marks, Patrick Stancombe, Kei Roger Aoki, Joseph Francis, Lance Steward
Abstract: The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the tissues of the immune system in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates and other materials in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interactions with the immune system, coupled with disease models to provide a more complete representation of an immune response.
Type:
Grant
Filed:
July 9, 2010
Date of Patent:
November 22, 2011
Assignee:
Sanofi Pasteur Vaxdesign Corp.
Inventors:
William L. Warren, Heather Fahlenkamp, Russel G. Higbee, Eric M. Mishkin, Guzman Sanchez-Schmitz, Michael D. Rivard, Santosh Pawar
Abstract: A transmission/reception method and apparatus in an Orthogonal Frequency Division Multiplexing (OFDM)-based wireless communication system are provided, in which a data transmitter adaptively selects a multiplexing scheme according to a code rate of the transmission packet or an effective SNR of a wireless channel for a corresponding terminal, when transmitting a packet data channel. The adaptive multiplexing scheme is equal in concept to a scheme of adaptively implementing unitary precoding. The unitary precoded multiplexing includes Orthogonal Frequency code Domain Multiplexing (OFCDM), Fast Fourier Transform-Spread-OFDM (FFT-S-OFDM), Fast Frequency Hopping-OFDM (FFH-OFDM), and the like. The method and apparatus adaptively selects the multiplexing scheme and transmits/receives data using the selected multiplexing scheme, thereby improving reception performance of the packet data.
Type:
Grant
Filed:
May 4, 2006
Date of Patent:
November 22, 2011
Assignee:
Samsung Electronics Co., Ltd.
Inventors:
Hwan-Joon Kwon, Joon-Young Cho, Yun-Ok Cho, Ju-Ho Lee, Dong-Hee Kim, Jin-Kyu Han, Achim Seebens, Peter Jung, Tobias Scholand
Abstract: Provided herein are antibodies, such as fully human antibodies that immunospecifically bind to an hLIGHT polypeptide. Also provided are isolated nucleic acids encoding antibodies, such as fully human antibodies, that immunospecifically bind to a hLIGHT polypeptide. Further provided are vectors and host cells comprising nucleic acids encoding antibodies, such as fully human antibodies, that immunospecifically bind to a hLIGHT polypeptide. Also provided are methods of making antibodies, such as fully human antibodies, that immunospecifically bind to a hLIGHT polypeptide. Also provided herein is a method of treating a hLIGHT-mediated disease in a subject comprising administering to the subject an antibody, such as a fully human antibody, that immunospecifically binds to a hLIGHT polypeptide. In preferred embodiments, that anti-hLIGHT antibodies provided herein will ameliorate, neutralize or otherwise inhibit hLIGHT biological activity in vivo (e.g.
Type:
Grant
Filed:
August 24, 2007
Date of Patent:
November 15, 2011
Assignees:
Kyowa Hakko Kirin, La Jolla Institute for Allergy and Immunology
Inventors:
Steven W. Granger, Shinichiro Kato, Carl F. Ware
Abstract: The present invention is directed to methods of diagnosing a disease or predicting an increased risk of a disease, such as obesity, obesity-dependent subacute inflammation, atherosclerosis, cardiovascular disease and a metabolic disease, by determining the levels of omentin 1 and 2 protein in a subject, or by determining the levels of omentin 1 and 2 gene expression in a subject. The present invention is also directed to methods of disease treatment using omentin 1 protein and omentin 2 protein.
Type:
Grant
Filed:
September 29, 2007
Date of Patent:
November 15, 2011
Assignee:
University of Maryland, Baltimore
Inventors:
Da-Wei Gong, John C. McLenithan, Alan R. Shuldiner, Rong-Ze Yang