Abstract: The present invention concerns a method for diagnosing liver fibrosis wherein two or more diagnostic markers are measured and the measurements are correlated by a mathematic algorithm characterized in that the diagnostic markers are selected from the group N-terminal procollagen III propeptide (PIIINP), Collagen IV, Collagen VI, Tenascin, Laminin, Hyaluronan, MMP-2, TIMP-1 and MMP-9/TIMP-1 complex. The algorithm can be used to predict the histological score of a liver biopsy.
Type:
Grant
Filed:
April 26, 2001
Date of Patent:
November 28, 2006
Inventors:
Michael Volker, Michael Becka, Werner Kroll, Andreas Knorr, Mathias Gehrmann, Guido Hennig, Sylvia Unger, Elmar-Reinhold Burchardt, Michael J. Arthur, Alastair D. Burt, Massimo Pinzani, Detlef Schuppan
Abstract: There is provided a cosmetic composition, preferably in the form of a nail polish, comprising a primary film former, one or more high-molecular weight polyurethanes, and, optionally, one or more arylsulfonamide epoxy resins.