Abstract: This invention relates to bicyclic lactams and derivatives thereof which are useful as converting enzyme inhibitors and as antihypertensives.
Type:
Grant
Filed:
July 15, 1983
Date of Patent:
April 28, 1987
Assignee:
Merck and Co., Inc.
Inventors:
Matthew J. Wyvratt, Jr., Eugene D. Thorsett, Edward W. Tristram, Arthur A. Patchett, Elbert E. Harris
Abstract: Compounds of the formula: ##STR1## and pharmaceutically acceptable salts thereof are inhibitors of angiotensin I converting enzyme and are useful as antihypertensive agents and are also useful as cholecystokinin antagonists.