Abstract: A modular spinal disc prosthesis, with up to three independent rotational and up to three independent translational degrees-of-freedom. The prosthesis can maintain non-separable, and non-restrictive, mechanical linkage by establishing a linked series of kinematic pairs between components. Embodiments can include a superior plate, fixedly attached to a superior vertebra in an FSU that links to a planar pair, which links to an orthogonal prismatic pair, which links to a spherical pair, which links to an inferior plate that is fixedly attached to an inferior vertebra of an FSU, completing the jointed kinematic chain. The subject invention can enforce the kinematic constraints to realize the kinematic pairs and can also limit the range of operation of the degrees of freedom for each pair. A surrounding, protective boot can be used to isolate the elements of the invention.

Abstract: The present invention relates to antibodies, antibody fragments, and derivatives thereof that specifically bind to TLR3 cell receptors present on the surface of cells. The invention also relates to hybridomas producing such antibodies; methods of making such antibodies; fragments, variants, and derivatives of the antibodies; pharmaceutical compositions comprising the same; methods of using the antibodies to detect TLR3 levels on the surface of cells, and the use of such antibodies and compositions for diagnostic or therapeutic purposes in subjects.

Abstract: Provided is an imaging lens, the imaging lens including in an orderly way from an object side, a first lens including an incidence surface having a positive (+) refractive power and incident with light, a reflecting surface reflecting the incident light and an exit surface outputting the reflected light; a second lens having a negative (?) refractive power; a third lens having a positive (+) refractive power; a fourth lens having a positive (+) refractive power; a fifth lens having a negative (?) refractive power; a sixth lens having a positive (+) refractive power; and a seventh lens having a positive (+) refractive power, wherein the second lens through the seventh lens are disposed in an orderly way from an exit surface of the first lens.

Abstract: Proteins (INSP141, INSP142, INSP143, and INSP144) identified as anthrax receptor-like proteins containing von Willebrand factor A (vWFA) and Anthrax receptor extracellular (ANT_IG) domains and the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease are described.

Abstract: The subject invention provides novel devices and methods for the detection of the presence and/or activity of proteases in biological samples.

Abstract: The invention relates to a sensor comprising a medium and, disposed therein, a hologram, wherein an optical characteristic of the medium changes as a result of a variation in a physical property of the medium, wherein the fringes of the hologram are formed by silver grains and wherein the medium comprises a material which does not bind silver. The brightness and sensitivity of such holographic sensors is increased as a result of reduction in the levels of unwanted (“background”) silver binding.