Patents Represented by Attorney, Agent or Law Firm Sally Yeager
  • Use of TIMP-3 inducers of TIMP-3 expression, and TIMP-3 mimetics to treat ocular neovascularization
    Patent number: 6534475
    Abstract: Methods and compositions for treating ocular neovascularization with TIMP-3, TIMP-3 inducers, and TIMP-3 mimetics are disclosed.
    Type: Grant
    Filed: October 26, 2000
    Date of Patent: March 18, 2003
    Assignee: Alcon, Inc.
    Inventor: Abbot F. Clark
  • Non-peptide bradykinin receptor antagonists for use in controlling intraocular pressure and treating glaucoma
    Patent number: 6500831
    Abstract: This invention relates to the topical ocular use of non-peptide bradykinin receptor antagonists to treat glaucoma and ocular hypertension.
    Type: Grant
    Filed: October 2, 2000
    Date of Patent: December 31, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventor: Najam A. Sharif
  • Use of inhibitors of gag synthesis for the treatment of corneal haze
    Patent number: 6399107
    Abstract: This invention relates to the compositions and methods for the treatment of corneal haze. The compositions and methods are particularly directed to the use of GAG synthesis inhibitors in the treatment of corneal haze.
    Type: Grant
    Filed: June 20, 2001
    Date of Patent: June 4, 2002
    Assignee: Alcon Laboratories, Inc.
    Inventors: Timothy L. Kessler, Jon C. Nixon, Karen C. David, Gustav Graff
  • Treatment of glaucoma and ocular hypertension
    Patent number: 6177427
    Abstract: Compositions of non-steroidal glucocorticoid antagonists for treating glaucoma or ocular hypertension and methods for their use are disclosed.
    Type: Grant
    Filed: July 1, 1999
    Date of Patent: January 23, 2001
    Assignee: Alcon Laboratories, Inc.
    Inventors: Abbot F. Clark, Raymond E. Conrow
  • Combination therapy for lowering and controlling intraocular pressure
    Patent number: 6172054
    Abstract: Angiostatic agents and another IOP lowering compound are combined in ophthalmic compositions to treat glaucoma and ocular hypertension. Methods for treating glaucoma and ocular hypertension are also disclosed.
    Type: Grant
    Filed: June 15, 1995
    Date of Patent: January 9, 2001
    Assignee: Alcon Laboratories, Inc.
    Inventor: Abbot F. Clark
  • Treatment of GLC1A glaucoma with glucocorticoid antagonists
    Patent number: 6090798
    Abstract: Compositions of glucocorticoid antagonists for treating mammals suffering from GLC1A glaucoma and methods for their use are disclosed.
    Type: Grant
    Filed: December 19, 1997
    Date of Patent: July 18, 2000
    Assignee: Alcon Laboratories, Inc.
    Inventor: Abbot F. Clark
  • Process for manufacturing ophthalmic suspensions
    Patent number: 6071904
    Abstract: Ophthalmic suspensions containing brinzolamide or brinzolamide and a beta-blocker and processes for manufacturing the suspensions are disclosed.
    Type: Grant
    Filed: July 2, 1997
    Date of Patent: June 6, 2000
    Assignee: Alcon Laboratories, Inc.
    Inventors: Yusuf Ali, Robert E. Beck, Rex C. Sport
  • TGF.alpha. for the treatment of ocular hypertension and glaucoma
    Patent number: 6071875
    Abstract: Compositions and methods for treating glaucoma and ocular hypertension by using TGF.alpha. are disclosed.
    Type: Grant
    Filed: May 19, 1999
    Date of Patent: June 6, 2000
    Assignees: Alcon Laboratories, Inc., University of North Texas Health Science Center at Fort Worth
    Inventors: Abbot F. Clark, Robert J. Wordinger
  • Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides
    Patent number: 6066671
    Abstract: Compositions of 3-benzoylphenylacetic acid derivatives for treating GLC1A glaucoma and methods for their use are disclosed.
    Type: Grant
    Filed: December 19, 1997
    Date of Patent: May 23, 2000
    Assignee: Alcon Laboratories, Inc.
    Inventors: John M. Yanni, Mark R. Hellberg
  • Treatment of GLC1A glaucoma with non-steroidal glucocorticoid antagonists
    Patent number: 6051573
    Abstract: Compositions of non-steroidal glucocorticoid antagonists for treating GLC1A glaucoma and methods for their use are disclosed.
    Type: Grant
    Filed: December 19, 1997
    Date of Patent: April 18, 2000
    Assignee: Alcon Laboratories, Inc.
    Inventor: Abbot F. Clark
  • Polymeric quaternary ammonium compounds and their use as ophthalmic antimicrobias
    Patent number: 6051611
    Abstract: The invention relates to polymeric quaternary ammonium compounds which are useful as disinfectants and/or preservatives in ophthalmic compostions.
    Type: Grant
    Filed: December 22, 1998
    Date of Patent: April 18, 2000
    Assignee: Alcon Laboratories, Inc.
    Inventors: Evan P. Kyba, Joonsup Park
  • Treatment of ischemic disorders of the retina and optic nerve head
    Patent number: 6020352
    Abstract: The use of polyamine site antagonists in treating ischemic disorders of the retina and optic nerve head are disclosed. Especially preferred are certain 1-phenyl-2-piperidinoalkanol derivatives, such as eliprodil and ifenprodil.
    Type: Grant
    Filed: November 18, 1997
    Date of Patent: February 1, 2000
    Assignee: Synthelabo
    Inventors: Michael A. Kapin, Louis Desantis, Jr., Bernard Scatton, Salomon Langer
  • Angiostatic steroids
    Patent number: 6011023
    Abstract: Methods and compositions for preventing and treating neovascularization with steroids is disclosed.
    Type: Grant
    Filed: August 27, 1997
    Date of Patent: January 4, 2000
    Assignee: Alcon Laboratories, Inc.
    Inventors: Abbot F. Clark, Raymond E. Conrow
  • Angiostatic agents and methods and compositions for controlling ocular hypertension
    Patent number: 5990099
    Abstract: Compositions of angiostatic agents for treating GLC1A glaucoma and methods for their use are disclosed.
    Type: Grant
    Filed: December 19, 1997
    Date of Patent: November 23, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventor: Abbot F. Clark
  • Compositions and method for disinfecting fabric
    Patent number: 5976462
    Abstract: Compositions for disinfecting fabric and preventing spread of contamination are disclosed. Methods for their use are also contemplated.
    Type: Grant
    Filed: July 18, 1997
    Date of Patent: November 2, 1999
    Inventors: Ralph P. Stone, Billie M. York, Rodney P. Horn, Jeffrey S. Kiel
  • Steroids which inhibit angiogenesis
    Patent number: 5972922
    Abstract: Novel angiostatic .DELTA..sup.4,9(11) -steroids (I), ##STR1## C.sub.21 -oxygenated steroids (II) and other known steroidal compounds have been found to be useful in treating angiogenesis in mammals who have a need for the same. These steroids are useful in treating diseases of neovascularization such as cancer, diabetes and arthritis.
    Type: Grant
    Filed: December 21, 1995
    Date of Patent: October 26, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: John W. Wilks, Thomas F. DeKoning, Paul A. Aristoff
  • Treatment of retinal edema with brinzolamide
    Patent number: 5948801
    Abstract: Methods for preventing and treating retinal edema with brinzolamide are disclosed.
    Type: Grant
    Filed: March 9, 1998
    Date of Patent: September 7, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Rupa Doshi, Michael A. Kapin
  • Topical anti-glaucoma compositions
    Patent number: 5932572
    Abstract: Ophthalmic pharmaceutical compositions useful in controlling elevated intraocular pressure associated with glaucoma and ocular hypertension are described. The compositions comprise a combination of a beta-blocker and a carbonic anhydrase inhibitor to reduce the production of aqueous humor, preferably formulated as a suspension having a pH between about 6.8 and about 7.8. These compositions may additionally contain a mucomimetic anionic polymer and/or a finely-divided drug carrier substrate to provide sustained release. A method of controlling elevated intraocular pressure with these compositions is also described.
    Type: Grant
    Filed: August 27, 1997
    Date of Patent: August 3, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Thomas R. Dean, Louis Desantis, Jr.
  • Combination therapy for treating glaucoma
    Patent number: 5883108
    Abstract: Methods for treating persons with glaucoma or ocular hypertension with polyamine antagonists and an IOP-lowering compounds are also disclosed.
    Type: Grant
    Filed: August 28, 1997
    Date of Patent: March 16, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventor: Louis DeSantis, Jr.
  • Prevention and treatment of ocular neovascularization using angiostatic steroids
    Patent number: 5770592
    Abstract: Methods and formulations for treating ocular neovascularization using angiostatic steroids are disclosed.
    Type: Grant
    Filed: July 16, 1997
    Date of Patent: June 23, 1998
    Assignee: Alcon Laboratories, Inc.
    Inventor: Abbot F. Clark