Abstract: Antibodies which neutralize botulinum neurotoxin serotype F are produced using biologically active botulinum neurotoxin instead of toxoid for immunization and exploiting the importance of cross reaction between various serotypes to obtain immune responses, or monoclonal antibodies, to additional serotypes of interest. Methods of preparation and uses of the neutralizing botulinum neurotoxin antibodies are described.

Abstract: Antisense oligonucleotides specific for the muscarinic type 2 acetylcholine receptor mRNA have been identified. Administration of these oligonucleotides to animals resulted in an increase in memory and learning. Methods for discovering other oligonucleotides with the same activity are taught, as are uses of the antisense molecules for treatment of human and animal diseases.

Abstract: Ths invention relates to a new and distinct fall bearing golden fruited raspberry cultivar named `Anne` which is capable of producing fruit on primocanes, the fruit being larger and more cohesive than that of the standard cultivars. The cultivar is characterized by moderate suckering ability, and its round-conic, light colored and symmetrical fruit. Additionally, it is characterized by its sparsely thorny upright canes, with fall fruit appearing on the upper quarter of the cane.

Abstract: This invention relates to a new and distinct fall bearing red raspberry cultivar named `Caroline` which is capable of producing a large amount of larger, more flavorful and more cohesive fruit on primocanes 1-3 weeks earlier than standard cultivars. The cultivar is characterized by its moderate to high suckering ability, its conic, smooth and symmetrical fruit. Additionally, its thorn characteristics and its upright canes with fall fruit appearing on the upper half of the cane.

Abstract: This invention relates to a new and distinct spring bearing red raspberry cultivar named `Lauren` which is capable of producing large fruit of floricanes that ripen 1 to 3 weeks earlier than `Titan`, the only other large fruited cultivar grown in the eastern United States, and several days to weeks earlier than most standard cultivars currently in widespread use. The cultivar is characterized by its moderate suckering ability, its conic, smooth and symmetrical fruit. Additionally, its canes are upright and vigorous, and it does not normally produce a fall crop.