Abstract: The invention provides a pharmaceutical combination comprising: a) a pyrimidylaminobenzamide compound, and b) imatinib. and a method for treating or preventing a proliferative disease, especially GIST, using such a combination.
Type:
Grant
Filed:
June 2, 2006
Date of Patent:
August 3, 2010
Assignee:
Novartis AG
Inventors:
Leila Alland, Paul W Manley, Juergen Mestan
Abstract: The invention relates to the compounds of formula: (I) which are as defined in the specification. Their use as chiral ligands in catalytic aryl transfer reactions to aromatic aldehydes is also described.