Patents Represented by Attorney SaraLynn Mendel
  • Patent number: 5041378
    Abstract: Xylose isomerase (XI) muteins useful in the conversion of glucose to fructose or xylose to xylulose are obtained in usable amounts by protein structural and recombinant DNA methods, including x-ray crystallography, cloning, computer graphic modeling and site-directed mutagenesis and expression of the bacterial DNA sequences encoding native procaryotic xylose isomerase. These native sequences are altered to encode the xylose isomerase muteins having improved catalytic function and/or thermostability.
    Type: Grant
    Filed: August 11, 1987
    Date of Patent: August 20, 1991
    Assignees: Cetus Corporation, Univerity of Oregon
    Inventors: Robert J. Drummond, Will Bloch, Brian W. Matthews, Pamela L. Toy