Abstract: A flexible surgical drape has an adhesive side and a non-adhesive side. The adhesive side is adhesive across substantially its entire face. The drape consists of a flexible sheet suitable for covering a substantial portion of a patient's body. A pocket for catching patient secretions and other fluids is attached to the adhesive side of the drape. The drape contains an opening capable of receiving a removable valve, which, when in place, seals off the opening and prevents the passage of gases, secretions, and fluids that are typically present during a medical procedure. The valve can be made to lock into the opening so as to reduce the likelihood of its inadvertent removal. An examining tool such as a colonoscope fits through a hole extending through the valve and thus can be passed from one side of the drape to the other.