Abstract: A carrier composition for cutaneously absorbable topical pharmaceutical formulations of pharmacologically active agents is disclosed which comprises at least one partial glyceride of a fatty acid of medium chain length. This vehicle enhances the permeation of the topical formulation through the skin. A topical formulation which comprises this permeation enhancing vehicle is suitable for cutaneously applying pharmacologically active agents which are locally and/or systematically effective in the body.
Type:
Grant
Filed:
February 22, 1978
Date of Patent:
April 21, 1981
Assignee:
Kali-Chemie Pharma GmbH
Inventors:
Theodor Eckert, Fritz H. Kemper, Martin Wischniewski, Reinhard Hempel