Abstract: An embodiment of a method uses an implantable device to deliver a heart failure therapy to a patient. The device is used to sense unintended motion of the patient caused by the neural stimulation and identify a sensed motion level for the sensed unintended motion, and to sense physiological activity of the patient, different than the sensed motion, and identify a sensed physiological activity level. Delivering the heart failure therapy includes delivering neural stimulation through an electrode to a neural target in an autonomic nervous system of the patient using the implantable device. The sensed motion level, the sensed physiological activity level, and the programmed mapping are used to determine the neural stimulation intensity level of the neural stimulation to be delivered for the motion level.

Abstract: A device and method for delivering electrical stimulation to the heart in order to improve cardiac function in heart failure patients. The stimulation is delivered as high-output pacing in which the stimulation is excitatory and also of sufficient energy to augment myocardial contractility. In order to provide a consistent hemodynamic response, the high-output pacing is optimized by delivering it using different parameter sets, evaluating the hemodynamic response thereto as reflected by one or more measured physiological variables, and selecting the parameter set with the best hemodynamic response.

Abstract: The compositions comprise an effective repellent amount of one or more monoterpenoids, one or more sesquiterpenoids or a blend of one or more monoterpenoids and one or more sesquiterpenoids in combination with a carrier, wherein the compositions are formulated to repel a target pest from a target area. In one embodiment, the one or more monoterpenoids, and/or one or more sesquiterpenoids are from a biorational source, such as a plant volatile. In one embodiment, the one or more sesquiterpenoids are oxygen-containing sesquiterpenoids. In a particular embodiment, the plant volatile is a monoterpenoid, such as “nepetalactone” (or the individual nepetalactone isomers) derived from catnip (Nepeta cataria). In another embodiment, the plant volatile is additionally or alternatively a sesquiterpenoid derived from the fruit of the Osage orange tree (Maclura pomifera), Siam wood or the Amyris plant. Such compositions have repellency, including long term repellency, against arthropods.