Patents Represented by Attorney Sci-Law Strategies, PC
-
Patent number: 8325346Abstract: An apparatus may include a flow cell for a surface plasmon resonance test apparatus and a fluid delivery system operatively coupled to the flow cell and configured to deliver a plurality of fluids to the flow cell substantially continuously. The fluid delivery system may include two pumps for pumping the fluids.Type: GrantFiled: January 9, 2012Date of Patent: December 4, 2012Assignee: Plexera LLCInventors: Gibum Kim, Hannwen Guan, Shuxin Cong
-
Patent number: 8264691Abstract: Instruments and methods relating to surface plasmon imaging are described. An instrument comprises a semi-circular rail and a driving mechanism. The driving mechanism is attached to a light source mount and a detector mount, and both the light source mount and the detector mount are attached to the semi-circular rail with connectors. Each connector allows the light source mount and detector mount to slide along the rail. The synchronous movement of the light source mount and the detector mount changes the angle of incidence of a light beam from the light source with respect to the plane of the sample surface on the sample stage.Type: GrantFiled: December 1, 2010Date of Patent: September 11, 2012Assignee: Plexera, LLCInventors: Hann-Wen Guan, Shuxin Cong
-
Patent number: 8263377Abstract: This disclosure describes methods and compositions for measuring the binding specificity, kinetics and affinity of kinase inhibitors indirectly using mass sensing analytical techniques, such as SPR, through the competitive displacement of detectable signal-inducing kinase binding molecule. Further provided are methods for preparing such molecules.Type: GrantFiled: April 2, 2008Date of Patent: September 11, 2012Assignee: Plexera, LLCInventors: Ronald P Dudek, Michael Cicirelli, Timothy C Parker
-
Patent number: 8244602Abstract: The present invention relates to methods of manufacturing lightweight thermoplastic dunnage platform decks or repairing and reusing damaged lightweight thermoplastic dunnage platform decks to be mounted with molded feet. In an embodiment of the present invention, a dunnage platform with damaged feet is modified such that the damaged feet are removed and replacement feet are attached. In an embodiment of the present invention, the damaged feet of a dunnage platform are removed and the resulting dunnage platform deck is shipped to a desired site whereupon molded feet are attached to the dunnage platform deck and the dunnage platform generated from the deck and molded feet is used for shipping cargo.Type: GrantFiled: September 29, 2009Date of Patent: August 14, 2012Assignee: Airdex International, Inc.Inventor: Vance L. Seagle
-
Patent number: 8224719Abstract: The present invention provides a dunnage platform bag that is light weight, strong, made of a fire retardant material and which forms an ultra violet light, weather and dust particle barrier to protect the integrity of the dunnage platforms when not in use. A system and method for supplying, dispensing, positioning, tracking, transporting, forwarding and storing dunnage platforms based on the dunnage platforms bag is disclosed. In an embodiment of the invention, a modified dunnage platform made up of a dunnage platform base and attached legs can be stored in the dunnage platform bag.Type: GrantFiled: November 11, 2009Date of Patent: July 17, 2012Assignee: Airdex International, Inc.Inventors: Vance L. Seagle, Philip J. Tschirn
-
Patent number: 8224721Abstract: A dunnage platform adapted to support a load for transport comprises a deck including a top surface, a bottom surface and an edge extending therebetween and a pair of legs, each of the legs including at least one foot extending from the leg. The bottom surface of the deck includes at least one stub for each of the legs, the at least one stub positioning the leg along the bottom surface. The at least one foot of each leg is hollow to receive the at least one stub. When the pair of legs is positioned along the deck, the dunnage platform is elevated by the at least one foot extending from the each said leg of the pair of legs.Type: GrantFiled: February 10, 2011Date of Patent: July 17, 2012Assignee: Airdex International, Inc.Inventor: Vance L. Seagle
-
Patent number: 8217341Abstract: In various embodiments of the invention, a device permits more efficient collection and transmission of ions produced by the action of a carrier gas containing metastable neutral excited-state species into a mass spectrometer. In one embodiment of the invention, the device incorporates the source for ionization in combination with a jet separator to efficiently remove excess carrier gas while permitting ions to be more efficiently transferred into the vacuum chamber of the mass spectrometer. In an embodiment of the invention, improved collection of ions produced by the carrier gas containing metastable neutral excited-state species at greater distances from between the position of the analyte and the position of the mass spectrometer are enabled.Type: GrantFiled: January 6, 2010Date of Patent: July 10, 2012Assignee: IonsenseInventor: Brian D. Musselman
-
Patent number: 8207497Abstract: In various embodiments of the invention, a cargo container can be monitored at appropriate time intervals to determine that no controlled substances have been shipped with the cargo in the container. The monitoring utilizes reactive species produced from an atmospheric analyzer to ionize analyte molecules present in the container which are then analyzed by an appropriate spectroscopy system. In an embodiment of the invention, a sorbent surface can be used to absorb, adsorb or condense analyte molecules within the container whereafter the sorbent surface can be interrogated with the reactive species to generate analyte species characteristic of the contents of the container.Type: GrantFiled: May 7, 2010Date of Patent: June 26, 2012Assignee: IonSense, Inc.Inventor: Brian D. Musselman
-
Patent number: 8163363Abstract: A dunnage platform is in the general shape of a rectangular slab with legs extending form one side. The dunnage platform is made from an expanded polystyrene core. A chemical combination process is used to chemically combine portion of the core proximal to its surface with high impact polystyrene. In a first of two parts of the combination process, the core is placed in a forming mold with one of its two sides and two thirds of its thickness extending therefrom. A heated sheet of high impact polystyrene is brought into contact with the portion of the core extending from the mold. In a similar manner, the other of the two sides of the core is made to extend from the forming mold for contact with a heated sheet of high impact polystyrene.Type: GrantFiled: January 14, 2011Date of Patent: April 24, 2012Assignee: Airdex International, Inc.Inventor: Laurence W Dummett
-
Patent number: 8142589Abstract: A dunnage platform is in the general shape of a rectangular slab with legs extending form one side. The dunnage platform is made from an expanded polystyrene core. A chemical combination process is used to chemically combine portion of the core proximal to its surface with high impact polystyrene. In a first of two parts of the combination process, the core is placed in a forming mold with one of its two sides and two thirds of its thickness extending therefrom. A heated sheet of high impact polystyrene is brought into contact with the portion of the core extending from the mold. In a similar manner, the other of the two sides of the core is made to extend from the forming mold for contact with a heated sheet of high impact polystyrene.Type: GrantFiled: May 12, 2009Date of Patent: March 27, 2012Assignee: Airdex International, Inc.Inventor: Laurence W. Dummett
-
Patent number: 8107082Abstract: An apparatus may include a flow cell for a surface plasmon resonance test apparatus and a fluid delivery system operatively coupled to the flow cell and configured to deliver a plurality of fluids to the flow cell substantially continuously. The fluid delivery system may include two pumps for pumping the fluids.Type: GrantFiled: July 21, 2011Date of Patent: January 31, 2012Assignee: Plexera LLCInventors: Gilbum Kim, Hannwen Guan, Shuxin Cong
-
Patent number: 8094315Abstract: An article, process, and method for surface plasmon resonance plates are described. A substrate is covered with a thin metal film onto which a second thin metal film is deposited. The surface of the second thin metal film is converted to the metal oxide which is used to covalently bond organosilanes to the surface. Reactive organosilanes containing terminal bonding groups are arranged in a plurality of spots that are surrounded by inert organosilanes. Biomolecule attachment to the binding group is detected or measured from surface plasmon signals from the first thin metal film.Type: GrantFiled: December 8, 2008Date of Patent: January 10, 2012Assignee: Plexera LLCInventors: Nicholas Adam Wolf, Danliang Jin, Anna Barklund, Raluca Dinu
-
Patent number: 8026477Abstract: In various embodiments of the invention, a device permits more efficient collection and transmission of ions produced by the action of a carrier gas containing metastable neutral excited-state species into a mass spectrometer. In one embodiment of the invention, the device incorporates the source for ionization in combination with a jet separator to efficiently remove excess carrier gas while permitting ions to be more efficiently transferred into the vacuum chamber of the mass spectrometer. In an embodiment of the invention, improved collection of ions produced by the carrier gas containing metastable neutral excited-state species at greater distances from between the position of the analyte and the position of the mass spectrometer are enabled.Type: GrantFiled: November 20, 2008Date of Patent: September 27, 2011Assignee: Ionsense, Inc.Inventor: Brian D. Musselman
-
Patent number: 8004669Abstract: An apparatus may include a flow cell for a surface plasmon resonance test apparatus and a fluid delivery system operatively coupled to the flow cell and configured to deliver a plurality of fluids to the flow cell substantially continuously. The fluid delivery system may include two pumps for pumping the fluids.Type: GrantFiled: December 18, 2008Date of Patent: August 23, 2011Assignee: Plexera LLCInventors: Gibum Kim, Hannwen Guan, Shuxin Cong
-
Patent number: 7959578Abstract: An apparatus and method of collecting elements of and assembling various portions of ocular micro motions such as ocular micro-tremor (OMT) movements of the eye, and correlating them directly with OMT waveforms acquired from both known and unknown states of cognition and cognitive function. Comparing newly acquired waveforms from patients with undiagnosed cognitive dysfunctions, permits an individual or caregiver the ability to identify those unknown issues or cognitive states based on matching or relating statistically elements of their waveform with categories of other known cognitive processing normals and abnormals, functional and dysfunctional individuals. It also allows for measuring the effects of therapeutic agents (psychological or pharmacological) by relating them to measurable changes in cognitive function as a result of correlated changes in waveforms.Type: GrantFiled: January 29, 2009Date of Patent: June 14, 2011Inventor: Martin L. Lonky
-
Patent number: 7935094Abstract: The invention provides a surgical vacuum device including a vacuum cup sized for attachment to and manipulation of a target tissue. The device further includes a vacuum hose for applying a vacuum to the interior of the cup, and structure for applying a tensioning force to the cup once it has been placed and a vacuum applied. The vacuum device may be utilized with minimal or no trauma to the target tissue or surrounding tissues.Type: GrantFiled: October 2, 2003Date of Patent: May 3, 2011Assignee: Meditech Development IncorporatedInventor: Neal M. Lonky
-
Patent number: 7928364Abstract: The invention provides for efficient collection of analyte ions and neutral molecules from surfaces for their subsequent analysis with spectrometry. In an embodiment of the invention, a ‘multiple desorption ionization source’ includes a tube which can contain ions for subsequent sampling within a defined spatial resolution from desorption ionization at or near atmospheric pressures. In an embodiment, electrostatic fields are used to direct ions a plurality of tubes positioned in close proximity to the surface of the sample being analyzed. In an embodiment of the present invention, either narrow inside diameter capillary tubes or wide diameter tubes can be used in combination with a vacuum inlet to draw ions and neutrals into the spectrometer for analysis. In an embodiment of the invention, a dopant is introduced into a tube to analyze the sample. In an embodiment of the invention, a plurality of ionization sources is used to analyze the sample.Type: GrantFiled: October 15, 2007Date of Patent: April 19, 2011Assignee: IonSense, Inc.Inventor: Brian D. Musselman
-
Patent number: 7905049Abstract: Methods and systems for algae production are provided, the methods and systems generally comprising providing at least one body of water having an algae population in suspension, growing algae, heating the body of water with a heat source, heating the algae process with a heat source, drying the algae with a heat source, and covering the body of water with a cover. Heat recovery systems, algae processing, and covers are also provided.Type: GrantFiled: November 1, 2007Date of Patent: March 15, 2011Assignee: Independence Bio-Products, Inc.Inventor: Ronald A. Erd
-
Patent number: 7889347Abstract: Instruments and methods relating to surface plasmon imaging are described. An instrument comprises a semi-circular rail and a driving mechanism. The driving mechanism is attached to a light source mount and a detector mount, and both the light source mount and the detector mount are attached to the semi-circular rail with connectors. Each connector allows the light source mount and detector mount to slide along the rail. The synchronous movement of the light source mount and the detector mount changes the angle of incidence of a light beam from the light source with respect to the plane of the sample surface on the sample stage.Type: GrantFiled: November 21, 2006Date of Patent: February 15, 2011Assignee: Plexera LLCInventors: Hann-Wen Guan, Shuxin Cong
-
Patent number: RE43078Abstract: A non-radioactive atmospheric pressure device for ionization of analytes comprises an atmospheric pressure chamber having an inlet for carrier gas, a first electrode at one end, and a counter-electrode at the other end of the chamber for creating an electrical discharge in the carrier gas thus creating metastable neutral excited-state species. Optionally, a grid is provided to generate electrons or ions by contact with the excited-state species. The carrier gas containing the excited-state species or the electrons generated therefrom is directed at an analyte at atmospheric pressure near ground potential to form analyte ions.Type: GrantFiled: September 20, 2007Date of Patent: January 10, 2012Assignee: Jeol USA, Inc.Inventors: Robert B. Cody, James A. Laramee