Abstract: The present invention is directed to a method for producing a pyridopyrimidone of the formula wherein X is N or CH and R is an aryl, heteroaryl or alkyl group, said method comprising the step of reacting an acid derivative of the formula: wherein X is N or CH; Y is an appropriate leaving group; Z is a halogen, OR1, NHR1, or SR1; and R1 is a lower alkyl; and the amidine derivative is wherein R is an aryl, heteroaryl or alkyl group.
Type:
Grant
Filed:
December 31, 2004
Date of Patent:
October 10, 2006
Assignee:
Scios INC
Inventors:
Sarvajit Chakravarty, Sundeep Dugar, Richland Tester, Aurelia Conte