Abstract: This invention provides pharmaceutical compositions containing lipoxin compounds and therapeutic uses for the compounds in treating or preventing a disease or condition associated with columnar epithelial inflammation. The invention also discloses methods for screening for compounds useful in preventing columnar epithelial inflammation.
Type:
Grant
Filed:
February 25, 1997
Date of Patent:
August 8, 2000
Assignee:
The Brigham Women's Hospital, Inc.
Inventors:
James L. Madara, Charles N. Serhan, Sean P. Colgan