Patents Represented by Attorney Scott G. Hallquist
  • Patent number: 5543320
    Abstract: Mammalian Interleukin-7 receptor proteins, DNAs and expression vectors encoding mammalian IL-7 receptors, antibodies to mammalian Interleukin 7 receptors and processes for producing mammalian IL-7 receptors as products of recombinant cell culture, are disclosed.
    Type: Grant
    Filed: June 25, 1993
    Date of Patent: August 6, 1996
    Assignee: Immunex Corporation
    Inventors: Linda S. Park, Raymond G. Goodwin
  • Patent number: 5422248
    Abstract: Mammalian granulocyte-colony stimulating factor (G-CSF) receptor proteins, DNAs and expression vectors encoding mammalian G-CSF receptors, and processes for producing mammalian G-CSF receptors as products of recombinant cell culture, are disclosed.
    Type: Grant
    Filed: January 15, 1993
    Date of Patent: June 6, 1995
    Assignee: Immunex Corporation
    Inventors: Craig A. Smith, Alf D. Larsen, John E. Sims, Benson M. Curtis
  • Patent number: 5411865
    Abstract: A method for detecting anti-Leishmania parasite antibodies to a 230 kDa antigen present in Leishmania chagasi and Leishmania donovani is disclosed which comprises obtaining a sample from an individual, contacting the sample with a recombinant K39 repeat unit antigen comprising the amino acid sequence as shown in SEQ ID NO:3, and detecting the presence of anti-Leishmania parasite antibodies in the sample which bind to the recombinant K39 repeat unit antigen.
    Type: Grant
    Filed: January 15, 1993
    Date of Patent: May 2, 1995
    Assignee: Iasys Corporation
    Inventor: Steven Reed
  • Patent number: 5376367
    Abstract: A fusion protein which comprises MGF and IL-3. Such fusion proteins have enhanced biological activity.
    Type: Grant
    Filed: November 22, 1991
    Date of Patent: December 27, 1994
    Assignee: Immunex Corporation
    Inventor: Douglas E. Williams
  • Patent number: 5359039
    Abstract: Isolated viral proteins, and pharmaceutical compositions made therefrom, are disclosed which are capable of binding to Tumor Necrosis Factor, thereby functioning as Tumor Necrosis Factor antagonists. Also disclosed are processes for preparing isolated viral protein cytokine antagonists.
    Type: Grant
    Filed: July 9, 1993
    Date of Patent: October 25, 1994
    Assignee: Immunex Corporation
    Inventors: Craig A. Smith, Raymond G. Goodwin
  • Patent number: 5350683
    Abstract: Type II IL-1 receptor (type II IL-1R) proteins, DNAs and expression vectors encoding type II IL-1R, and processes for producing type II IL-1R as products of recombinant cell culture, are disclosed.
    Type: Grant
    Filed: July 12, 1993
    Date of Patent: September 27, 1994
    Assignee: Immunex Corporation
    Inventors: John E. Sims, David J. Cosman, Stephen D. Lupton, Bruce A. Mosley, Steven K. Dower
  • Patent number: 5328987
    Abstract: The present invention provides an isolated DNA sequence encoding soluble and membrane bound forms of a mammalian IgA Fc receptor, as well as recombinant expression vectors and host cells suitable for expressing the protein.
    Type: Grant
    Filed: November 4, 1992
    Date of Patent: July 12, 1994
    Assignee: Immunex Corporation
    Inventor: Charles R. Maliszewski
  • Patent number: 5319071
    Abstract: Substantially purified and homogeneous soluble human interleukin-1 receptor (shuIL-1R) proteins, DNA encoding the shuIL-1R proteins and pharmaceutical compositions containing the shuIL-1R proteins are described.
    Type: Grant
    Filed: January 14, 1992
    Date of Patent: June 7, 1994
    Assignee: Immunex Corporation
    Inventors: Steven K. Dower, Carl J. March, John Sims, David L. Urdal
  • Patent number: 5298395
    Abstract: Ligand reagents are disclosed which consist essentially of recombinant hyperglycosylated cytokines, expressed in yeast, which are purified and conjugated to various functional moieties, for example, biotin groups, via oligosaccharide residues. Methods of using such ligand reagents are also disclosed.
    Type: Grant
    Filed: November 5, 1992
    Date of Patent: March 29, 1994
    Assignee: Immunex Corporation
    Inventor: Linda S. Park
  • Patent number: 5296592
    Abstract: Mammalian Interleukin-1 receptor proteins (IL-1Rs), DNAs and expression vectors encoding mammalian IL-1Rs, and processes for producing mammalian IL-1Rs as products of cell culture, including recombinant systems, are disclosed.
    Type: Grant
    Filed: March 1, 1993
    Date of Patent: March 22, 1994
    Assignee: Immunex Corporation
    Inventors: Steven K. Dower, Carl J. March, John E. Sims, David L. Urdal
  • Patent number: 5266311
    Abstract: Cloning and expression of DNA segments encoding bovine IL-1.alpha., and processes for producing purified bovine IL-1.alpha. as a product of recombinant cell culture, are disclosed.
    Type: Grant
    Filed: December 23, 1991
    Date of Patent: November 30, 1993
    Assignee: Immunex Corporation
    Inventors: Douglas P. Cerretti, Charles R. Maliszewski, Michael Schoenborn
  • Patent number: 5264416
    Abstract: Mammalian Interleukin-7 receptor proteins, DNAs and expression vectors encoding mammalian IL-7 receptors, and processes for producing mammalian IL-7 receptors as products of recombinant cell culture, are disclosed.
    Type: Grant
    Filed: June 1, 1992
    Date of Patent: November 23, 1993
    Assignee: Immunex Corporation
    Inventors: Linda S. Park, Raymond G. Goodwin
  • Patent number: 5223605
    Abstract: Isolated and purified Interleukin-4 Binding Protein-.gamma. (IL-4bp.gamma.) and methods for obtaining isolated and purified IL-4bp.gamma..
    Type: Grant
    Filed: October 16, 1990
    Date of Patent: June 29, 1993
    Assignee: Immunex Corporation
    Inventors: William C. Fanslow, Richard J. Armitage
  • Patent number: 5217881
    Abstract: Ligand reagents are disclosed which consist essentially of recombinant hyperglycosylated cytokines, expressed in yeast, which are purified and conjugated to various functional moieties, for example, biotin groups, via oligosaccharide residues.
    Type: Grant
    Filed: January 24, 1992
    Date of Patent: June 8, 1993
    Assignee: Immunex Corporation
    Inventor: Linda S. Park
  • Patent number: 5202118
    Abstract: Wound healing compositions comprising IL-1.alpha. and IL-1.beta. proteins in a physiologically acceptable hydrophilic vehicle are used to promote wound healing.
    Type: Grant
    Filed: May 6, 1991
    Date of Patent: April 13, 1993
    Assignee: Immunex Corporation
    Inventors: Steven Gillis, Cindy A. Jacobs
  • Patent number: 5194375
    Abstract: Mammalian Interleukin-7 receptor proteins, DNAs and expression vectors encoding mammalian IL-7 receptors, and processes for producing mammalian IL-7 receptors as products of recombinant cell culture, are disclosed.
    Type: Grant
    Filed: May 21, 1990
    Date of Patent: March 16, 1993
    Assignee: Immunex Corporation
    Inventors: Linda S. Park, Raymond G. Goodwin
  • Patent number: 5162111
    Abstract: Subjects suffering from infectious diseases are treated by direct administration of therapeutically-effective quantities of granulocyte-macrophage colony stimulating factor employed by itself or in conjunction with an antibiotic or a sulfonamide or other immunologically effective therapeutic agents. Homogeneous granulocyte-macrophage colony stimulating factor for use in treatment in bacterial diseases is prepared by recombinant DNA techniques and then purified to homogeneity by reverse phase high-performance liquid chromatography so that it may be safely administered to subject's suffering from infectious diseases.
    Type: Grant
    Filed: July 30, 1986
    Date of Patent: November 10, 1992
    Inventors: Kenneth H. Grabstein, Philip J. Morrissey
  • Patent number: 5128450
    Abstract: The present invention provides a pharmaceutical compositions comprising as active ingredients certain truncated purified human IL-3(Pro.sup.8 Asp.sup.15 Asp.sup.70) analog proteins expressed by transformed yeast of the species Saccharomyces cerevisiae, which when administered to a primate do not result in detectable urticaria.
    Type: Grant
    Filed: June 30, 1989
    Date of Patent: July 7, 1992
    Inventors: David L. Urdal, Helmut M. Sassenfeld
  • Patent number: 5108911
    Abstract: A process for preparing bovine interleukin I.beta. (bIL-1.beta.) by culturing a microbial host transformed by a vector containing a DNA sequence encoding bIL-1.beta. under conditions suitable for the expression of bIL-1.beta. and recovering bIL-1.beta..
    Type: Grant
    Filed: August 11, 1989
    Date of Patent: April 28, 1992
    Assignee: Immunex Corporation
    Inventors: Douglas P. Cerretti, Brian S. Davis, Charles R. Maliszewski
  • Patent number: 5106733
    Abstract: Cloning and expression of DNA segments encoding bovine GM-CSF, and processes for producing recombinant bovine GM-CSF as a product of recombinant cell culture, are disclosed.
    Type: Grant
    Filed: May 22, 1989
    Date of Patent: April 21, 1992
    Assignee: Immunex Corporation
    Inventors: Paul E. Baker, Douglas P. Cerretti, William R. Clevenger, David J. Cosman, Charles R. Maliszewski