Patents Represented by Attorney Scully, Scott, Myrphy & Presser, P.C.

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  • Substituted 2-amino-4-phenyldihydroquinolines, processes for their preparation, pharmaceutical compositions and methods for their use
    Patent number: 8106204
    Abstract: The invention relates to NHE-3 inhibitor compounds of formula I: In which R1-R11 are more specifically defined herein. These substituted 2-amino-4-phenyl-dihydroquinolines are useful the treatment of various renal and respiratory disorders such as acute or chronic renal failure, for impairments of biliary function and respiratory impairments such as snoring, sleep apneas or stroke. Formulations comprising them and methods for their use are also described herein.
    Type: Grant
    Filed: September 17, 2008
    Date of Patent: January 31, 2012
    Assignee: Sanofi-Aventis
    Inventors: Hans-Jochen Lang, John Weston, Uwe Heinelt