Patents Represented by Attorney Seed and Bery, LLP
  • Patent number: 6063371
    Abstract: The biological activity of exogenous ligand proteins is enhanced by intravenously co-administering to a mammal the ligand and a soluble receptor protein that binds thereto. Pharmaceutical compositions comprising a ligand protein complexed with a soluble receptor protein are provided. In certain embodiments, the ligand is selected from the group consisting of interleukins, colony stimulating factors, and tumor necrosis factor.
    Type: Grant
    Filed: September 16, 1996
    Date of Patent: May 16, 2000
    Assignees: Immunex Corporation, The United States of America as represented by the Secretary of the Army
    Inventors: Charles R. Maliszewski, Fred D. Finkelman