Patents Represented by Law Firm Senniger, Powers, Leavitt & Roadel
  • Patent number: 5618916
    Abstract: A method for the treatment of superficial urinary tract tumors in a mammal involves administering a diagnostically effective amount of a liposomal composition comprising a liposome, a chemotherapeutic agent or immune activating drug carried by the liposome and a purified protein which functions as a mycobacterial receptor for fibronectin on the surface of the liposome whereby the liposomal composition becomes attached to and internalized in the cells of the tumors. In lieu of the purified protein an antibody to an integrin receptor on the surface of the cells of the tumors may be used or a delivery system composed of a conjugate of a chemotherapeutic agent or immune activating drug and an antibody to an integrin receptor may be employed.
    Type: Grant
    Filed: June 24, 1994
    Date of Patent: April 8, 1997
    Assignee: The Jewish Hospital of St. Louis
    Inventors: Timothy J. Ratliff, Eric J. Brown