Patents Represented by Attorney Seth Jacobs

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  • 5-oxo-pyrrolidine-2-carboxylic acid hydroxamide derivatives
    Patent number: 6114361
    Abstract: The present invention relates to a compound of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 are as defined above, to pharmaceutical compositions and methods of treatment.
    Type: Grant
    Filed: October 29, 1999
    Date of Patent: September 5, 2000
    Assignee: Pfizer Inc.
    Inventors: Ralph P. Robinson, Ellen R. Laird
  • Derivatives of 2-(2-oxo-ethylidene)-imidazolidin-4-one and their use as farnesyl protein transferase inhibitors
    Patent number: 6071935
    Abstract: The present invention relates to compounds of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula I and to methods of inhibiting abnormal cell growth, including cancer, in a mammal by administering the compounds of formula I to said mammal.
    Type: Grant
    Filed: October 7, 1999
    Date of Patent: June 6, 2000
    Assignee: Pfizer Inc.
    Inventor: Joseph P. Lyssikatos
  • Pyrazolopyrimidines for treatment of CNS disorders
    Patent number: 6051578
    Abstract: This invention relates to the use of pyrazolopyrimidines and pyrrolopyrimidine of, respectively, the general formula ##STR1## wherein A, X, R.sup.3, R.sup.4 and R.sup.5 are as defined below, and the pharmaceutically acceptable salts of such compounds, to treat, prevent or inhibit certain neuronal and other disorders.
    Type: Grant
    Filed: September 10, 1998
    Date of Patent: April 18, 2000
    Assignee: Pfizer Inc.
    Inventor: Yuhpyng L. Chen