Patents Represented by Attorney, Agent or Law Firm Sheldon O. Weber
  • Use of CNTF (ciliary neurotrophic factor) receptor activators for the treatment of obesity
    Patent number: 6565869
    Abstract: The present invention refers to the use of hCNTF (human ciliary neurotrophic factor), mutants thereof or other molecules that activate the CNTF receptor, for the preparation of drugs for the treatment of obesity and associated disease, for example hyperglycemia. FIG. 1 shows the anti-obesity effect of hCNTF and leptin on body weight (left panels) and on food intake (right panels) in genetically obese mice and in mice with diet-induced obesity (DIO).
    Type: Grant
    Filed: July 19, 1999
    Date of Patent: May 20, 2003
    Assignee: Istituto di Ricerche di Biologia Molecolare P. Angeletti S.p.A.
    Inventors: Gennaro Ciliberto, Patrizia Costa, Giacomo Paonessa, Domenico Lazzaro, Isabelle Gloaguen, Annalise Di Marco, Anna De Martis, Ralph Laufer, Riccardo Cortese