Patents Represented by Law Firm Shelman & Shalloway
  • Modified HGP-30 heteroconjugates, compositions and methods of use
    Patent number: 6103239
    Abstract: A heteroconjugate is formed by linking a T cell binding ligand (TCBL) such as Peptide J of .beta.-2 microglobulin to a modified HGP-30 antigentic peptide fragment of p17 gag peptide, such as. for exampleATL YSV HQR IDV KDTKEA LEK IEE EQN KS (SEQ ID NO: 5)The heteroconjugate is effective in eliciting a THI directed immune response and provides a vaccine composition for treating or preventing AIDS.
    Type: Grant
    Filed: August 9, 1996
    Date of Patent: August 15, 2000
    Assignee: CEL-SCI Corporation
    Inventors: Daniel H. Zimmerman, Prem S. Sarin