Patents Represented by Attorney SmithKline Beecham Corporation-Corporate Intellectual Property-US

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  • Vaccine for prevention and treatment of HIV-infection
    Patent number: 7612173
    Abstract: This invention relates to novel HIV polypeptide and polynucleotide fusions of Gag, Pol and Nef which are useful in immunogenic compositions and vaccines. The invention relates in particular to a polypeptide which comprises Nef or an immunogenic fragment thereof, and p17 Gag and/or p24 Gag or immunogenic fragments thereof, wherein when both p17 and p24 Gag are present there is at least one HIV antigen or immunogenic fragment between them. The polypeptide may also comprise Pol or RT or an immunogenic fragment thereof.
    Type: Grant
    Filed: August 3, 2005
    Date of Patent: November 3, 2009
    Assignee: GlaxoSmithKline Biologicals, s.a.
    Inventors: Helge Abrecht, Martine Delchambre, Martine Marchand, Nathalie Louise Mathy, Philippe Jean Gervais Ghislain Permanne, Gerald Hermann Voss