Patents Represented by Attorney Speckman Law Group PLLC
  • Patent number: 8350003
    Abstract: The present invention relates to peptides comprising amino acids according to Formula I ((X)l(Y)m)n ??(I) wherein l, m and n are integers from 0 to 10; X and Y, which may be the same or different, are an amino acid selected from the group consisting of hydrophobic amino acids and/or cationic amino acids, together with methods for the use of the peptides in the treatment of microbial infections.
    Type: Grant
    Filed: June 28, 2011
    Date of Patent: January 8, 2013
    Assignee: Novabiotics Limited
    Inventor: Deborah O'Neil
  • Patent number: 8333303
    Abstract: Metering devices, particularly for adhesives and sealants, that can be placed on a flexible container by means of an adapted ring, a lever being connected to the ring, and pressing against the container, are known. The invention relates to a metering device whereon the lever is connected to the ring via a deformable spring plate. A push button is formed onto the lever as an extension. Thus, the one-piece metering device is inexpensive and can be produced without needing to be assembled.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: December 18, 2012
    Assignee: Kisling AG
    Inventor: Werner F. Dubach
  • Patent number: 8333672
    Abstract: A novel ball-striking implement, in particular a tennis, squash or badminton racket, is described, with a head frame (1; 13) comprising an impact surface and also a stem which is formed integrally thereon and has a handle, the impact surface being determined by at least one string (3; 19) which is stretched crosswise and forms string portions fastened to the head frame substantially parallel to one another. The string portions in holding elements (2; 15) on the inside of the head frame are guided in such a manner that the string portions are positioned in a single plane forming the impact surface.
    Type: Grant
    Filed: June 12, 2008
    Date of Patent: December 18, 2012
    Assignee: Tec Sportmanagement AG
    Inventor: Hubert Nagler
  • Patent number: 8324154
    Abstract: The present invention relates to cyclic cationic peptides and their use in the treatment of microbial infections.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: December 4, 2012
    Assignee: Novabiotics, Ltd.
    Inventor: Deborah O'Neil
  • Patent number: 8323240
    Abstract: An interventional catheter assembly has an operating head and catheter system that are inserted and navigated within a patient's body while an operator controls the system externally of the operating head. Fluidic communication is provided between the operating head and the external system controls, and rotation is provided to the operating head by means of an external drive system. Numerous system controls are provided, along with various operating systems, sealing assemblies, actuators, torque transfer systems, and the like are provided. Some systems and controls are provided in a control pod and some controls, as well as displays, are provided in a console unit. Control pod, catheter system and operating head may be provided as a sterile, single use interventional catheter system, while the console unit may be provided as a multiple use device that communicates with the sterile, single use interventional catheter system during operation.
    Type: Grant
    Filed: April 28, 2010
    Date of Patent: December 4, 2012
    Assignee: Medrad, Inc.
    Inventors: Edward I. Wulfman, Casey Torrance
  • Patent number: 8283182
    Abstract: A sample testing device for testing for the presence of a component of interest in a liquid sample comprises: (a) at least one capillary pathway which has an upstream end and a downstream end and which incorporates a reagent system capable of causing agglutination with said component to be detected (the test capillary); (b) preferably, but optionally, at least one capillary pathway having an upstream end and a downstream end (the control capillary); (c) a sampling region to which the liquid sample is applied and from which the sample is able to enter the upstream ends of the test capillary(s) and if present the control capillary(s); (d) a power source; (c) detection arrangements electrically associated with said power source for detecting the presence of liquid at a downstream region of said testing capillary(s) and if present the control capillary(s); (f) display means operated by said power source for indicating the result of the test; and (g) signal processing means associated with the power source, detect
    Type: Grant
    Filed: June 11, 2010
    Date of Patent: October 9, 2012
    Assignee: Platform Diagnostics Limited
    Inventors: Damian Joseph Peter Bond, Stephen John Minter, Timothy John Minter
  • Patent number: 8268561
    Abstract: A method of genetically screening large numbers of individuals to identify those individuals requiring follow-up testing for active Type I diabetes (T1D) is provided. The method includes obtaining a nucleic-acid containing biological sample from each individual and testing for the presence of specific combinations of HLA II alleles in the sample.
    Type: Grant
    Filed: April 8, 2009
    Date of Patent: September 18, 2012
    Assignee: Pacific Northwest Research Institute
    Inventors: William Hagopian, Hui Peng
  • Patent number: 8267968
    Abstract: Bone anchoring assemblies for use with minimally invasive surgery (MIS) techniques for dynamic stabilization of the spine, together with placement systems for use in such techniques are provided.
    Type: Grant
    Filed: June 24, 2009
    Date of Patent: September 18, 2012
    Assignee: NeuroPro Technologies, Inc.
    Inventors: Benjamin J. Remington, Daniel R. Baker, Keith W. Kirkwood
  • Patent number: 8232452
    Abstract: Higher eukaryotes sense microbes through perception of pathogen-associated molecular patterns (PAMPs). The flagellin receptor FLS2 represents so far the only known pattern recognition receptor (PRR) in Arabidopsis. Arabidopsis plants detect a variety of PAMPs including specific epitopes of the bacterial proteins flagellin and EF-Tu. Here, we show that flagellin and EF-Tu activate a common set of signalling events and defence responses, but without clear additive or synergistic effects. Treatment with either PAMP results in increased receptor sites for both PAMPs, a finding employed in a reverse-genetic approach to identify the receptor kinase EFR as the EF-Tu receptor. Transient expression of EFR in Nicotiana benthamiana results in formation of specific binding sites for EF-Tu, and responsiveness to this PAMP. Arabidopsis efr mutants show a higher frequency of T-DNA transformation by the bacterium Agrobacterium tumefaciens, revealing a role for EF-Tu perception in restricting this plant pathogen.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: July 31, 2012
    Assignee: Plant Bioscience Limited
    Inventors: Cyril Zipfel, Jonathan Dallas George Jones, Dagmar Renate Hann, John Paul Rathjen
  • Patent number: 8232102
    Abstract: The present invention relates to a method of delivery of a therapeutic agent to a target cell the method comprising targeting particles comprising the therapeutic agent to the cell using magnetic means to apply a magnetic force to said particles so as to tend to move said particles towards said magnetic means and at the same time moving said magnetic means.
    Type: Grant
    Filed: April 21, 2006
    Date of Patent: July 31, 2012
    Assignee: Nanotherics Ltd.
    Inventors: Jon Dobson, Christopher D. Batich
  • Patent number: 8189333
    Abstract: Ceramic inserts and hermetically sealed or sealable connectors incorporating a ceramic insert providing conductive pathways between opposing faces and/or side-walls and fabricated using multi-layer ceramic fabrication techniques are described. Conductive pads provided as metalized surfaces on the ceramic insert facilitate conductive communication between the conductive pathways transiting the ceramic inserts and conductive structures contacting the conductive pads, such as sockets, pins, wires, and the like.
    Type: Grant
    Filed: September 14, 2009
    Date of Patent: May 29, 2012
    Assignee: Pacific Aerospace & Electronics, Inc.
    Inventor: Nathan Foster
  • Patent number: 8173383
    Abstract: The present invention provides rapid diagnostic assays for the detection of Leishmania which can readily be used in the field, leading to more rapid treatment. In certain embodiments, the inventive assays, including ELISA and lateral flow assays, employ antibodies that may be effectively employed to detect the Leishmania major antigen TSA, which is present in both promastigotes grown in culture and in amastigotes. Such assays may be employed to detect the presence of cutaneous leishmaniasis in a subject using scrapings, biopsies, and/or aspirates taken from cutaneous lesions.
    Type: Grant
    Filed: January 24, 2011
    Date of Patent: May 8, 2012
    Assignee: InBios International, Inc.
    Inventors: Raymond L. Houghton, Steven G. Reed, Syamal Raychaudhuri
  • Patent number: 8168204
    Abstract: The present invention relates to antigenic polypeptides expressed by pathogenic microbes, including antigenic polypeptides encoded by the nucleic acid sequence of FIG. 1, vaccines comprising the antigenic polypeptides and therapeutic antibodies directed to the antigenic polypeptides.
    Type: Grant
    Filed: April 23, 2010
    Date of Patent: May 1, 2012
    Assignee: Absynth Biologics Ltd.
    Inventor: Simon J. Foster
  • Patent number: 8163288
    Abstract: The invention relates to antigenic polypeptides expressed by pathogenic microbes, vaccines comprising said polypeptides; therapeutic antibodies directed to said polypeptides and methods to manufacture said polypeptides, vaccines and antibodies.
    Type: Grant
    Filed: June 29, 2010
    Date of Patent: April 24, 2012
    Assignee: Absynth Biologics Limited
    Inventors: Simon J. Foster, Jorge Garcia-Lara
  • Patent number: 8142812
    Abstract: A formulation, especially a pharmaceutical formulation, comprises an active agent and a carrier for the active agent, wherein the carrier comprises a beta-limit dextrin. The formulation may be a bioadhesive pharmaceutical formulation in which the beta-limit dextrin acts as a mucoadhesive agent. The active agent is a pharmaceutically active agent or a flavour or fragrance which is intended for delivery into the buccal cavity. A use of beta-limit dextrin as a disintegrant, a dispersant, and a mucoadhesive agent is also described. Also described is a nutritional product such as an energy drink which includes beta-limit dextrin as an energy source.
    Type: Grant
    Filed: July 29, 2003
    Date of Patent: March 27, 2012
    Assignee: Glycologic Limited
    Inventors: Richard Frank Tester, Xin Qi
  • Patent number: 8142450
    Abstract: The present invention involves new interventional methods for reducing gastric volume, and thereby treating obesity. The procedures are generally performed laparoscopically and may generally be described as laparoscopic plication gastroplasty (LPG) in which, after obtaining abdominal access, spaced apart sites on a gastric wall are engaged and approximated to create one or more tissue folds that are then secured to produce one or more plications projecting into the gastrointestinal space. The serosal tissue may optionally be treated during the procedure to promote the formation of a strong serosa-to-serosa bond that ensures the long-term stability of the tissue plication. These procedures are preferably carried out entirely extragastrically (i.e. without penetrating through the gastrointestinal wall), thereby minimizing the risks of serious complications. Methods for reversing the procedure are also disclosed.
    Type: Grant
    Filed: March 13, 2008
    Date of Patent: March 27, 2012
    Assignee: Longevity Surgical, Inc.
    Inventors: Peter S. Harris, Barry Hal Rabin
  • Patent number: 8136286
    Abstract: Firearms and firearm components are constructed from bonded multi-metallic base materials comprising at least two dissimilar metallic materials having different properties, such as weight, density, wear resistance, durability, hardness, and the like, bonded to one another. The components are fabricated such that the metallic material having higher impact- and wear-resistance is positioned at areas that experience impact, or that include bearing points, wear points, and interfaces with other components, while a lighter weight metallic material is positioned at component locations that don't have rigorous material property requirements. The bonded multi-metallic materials may be explosively bonded multi-metallic materials.
    Type: Grant
    Filed: June 25, 2010
    Date of Patent: March 20, 2012
    Assignee: Pacific Aerospace & Electronics, Inc.
    Inventor: Nelson Clare Settles
  • Patent number: D658383
    Type: Grant
    Filed: February 18, 2011
    Date of Patent: May 1, 2012
    Assignee: Dentis Rx, LLC
    Inventors: Lauren Key, Cindy V. Roark
  • Patent number: D662128
    Type: Grant
    Filed: May 20, 2011
    Date of Patent: June 19, 2012
    Inventor: Paul Nuttall
  • Patent number: D662375
    Type: Grant
    Filed: September 3, 2010
    Date of Patent: June 26, 2012
    Assignee: Birchmeier Spruhtechnik AG
    Inventor: Claudio Carozza