Patents Represented by Law Firm Sprung, Horn, Kramer & Woods
  • Recombinant protein production
    Patent number: 5576194
    Abstract: Recombinant Factor VIII production is increased by supplementing the serum-free culture of mammalian host cells containing the gene therefor in a serum-free nutrient media with lipoprotein obtained from a mammalian source, preferably low density human lipoprotein or total bovine lipoprotein.
    Type: Grant
    Filed: October 1, 1993
    Date of Patent: November 19, 1996
    Assignee: Bayer Corporation
    Inventor: Sham Y. Chan
  • Preparation of stable graphite
    Patent number: 5575985
    Abstract: In the preparation of a graphite body suitable for use as a cathode in an electrolytic process, comprising the steps ofa) contacting a graphite body with a solution in at least one polyhydric alcohol having 2 to 4 carbon atoms of at least one of an iridium salt and rhodium salt for a time sufficient for the solution to penetrate through the surface of the graphite body to a depth of at least about 1 mm, andb) heating and then cooling the graphite body,the improvement which comprises effecting the heating by contacting the surface of the graphite body into which the solution has penetrated with a naked gas flame positioned above such surface, the graphite body being heated to about 200.degree. to 450.degree. C. for about 2 to 10 minutes.
    Type: Grant
    Filed: May 12, 1995
    Date of Patent: November 19, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Helmut Klotz, Hans D. Pinter
  • Process for the sterile filtration of milk
    Patent number: 5576040
    Abstract: The present invention relates to a process for obtaining sterile milk, wherein the calcium ion content is reduced preferably to half of the naturally occurring amount by means, for example, of ion exchange or dialysis, and the milk is then filtered sterile, and if desired calcium ions are added again to restore the natural content.The product thus obtained has all of the biological activities as well as virtually the original composition, but it is free of bacteria, fungi and spores and will keep for a longer time.
    Type: Grant
    Filed: July 29, 1994
    Date of Patent: November 19, 1996
    Assignee: Biotest Pharma GmbH
    Inventors: Wolfgang Moller, Wolfgang Stephan, Henry Hies
  • Phenylglycinamides of heterocyclically substitued phenylacetic acid derivatives
    Patent number: 5576342
    Abstract: Phenylglycinamides of heterocyclically substituted phenylacetic acid derivatives are prepared by reacting phenylacetic acids with glycinamides. The compounds can be used as active compounds in medicaments.
    Type: Grant
    Filed: March 18, 1994
    Date of Patent: November 19, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Ulrich M uller, J urgen Dressel, Peter Fey, Rudolf Hanko, Walter H ubsch, Thomas Kr amer, Matthias M uller-Gliemann, Martin Beuck, Stanislav Kazda, Stefan Wohlfeil, Andreas Knorr, Johannes-Peter Stasch, Siegfried Zaiss
  • Method of preventing local corrosion at weld joints
    Patent number: 5575867
    Abstract: A method of preventing corrosion damage at weld joints, in the heat affected zones of weld joints, and in heat-treated zones of components made of stainless steels having chromium contents .gtoreq.12% by weight, which comprises exposing weld joints and the heat affected zones of the weld joints, or the heat-treated zones, to a water vapor atmosphere at temperatures of 100.degree. to 250.degree. C. for five to sixty minutes.
    Type: Grant
    Filed: August 17, 1995
    Date of Patent: November 19, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventor: Michael Renner
  • 7-(aminomethyl-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)quinolonecarboxylic and 7-(aminomethyl-oxa-7-aza-bicyclo[3.3.0]oct-7-yl naphthyridonecarboxylic acid derivatives
    Patent number: 5574161
    Abstract: The invention relates to novel derivatives of quinolone-carboxylic acid and naphthyridonecarboxylic acid which are substituted in the 7 position by a 1- (or 5-)amino-methyl-2- (or 3-)oxa-7-aza-bicyclo[3.3.0]oct-7-yl residue, their salts, processes for their preparation and antibacterial agents containing these compounds.
    Type: Grant
    Filed: October 7, 1994
    Date of Patent: November 12, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Uwe Petersen, Thomas Schenke, Klaus Grohe, Klaus-Dieter Bremm, Rainer Endermann, Karl G. Metzger
  • Gel formers and gels, their preparation and use
    Patent number: 5573706
    Abstract: Gel formers and gels containa) acidic aluminium phosphates, optionally in the form of reaction products with 0.01 to 4 mol of alkanolamines per mol of aluminium phosphate, andb) reaction products of boric acid with alkanolamines, a) and b) being present in a weight ratio of 100:55 to 100:0.5, calculated as solids.
    Type: Grant
    Filed: October 26, 1993
    Date of Patent: November 12, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventor: Wulf von Bonin
  • Method for the mutual chemical and compaction treatment of inorganic wastes
    Patent number: 5574204
    Abstract: Water-containing inorganic waste materials, originally in loose form, and which contain water-soluble components capable of reacting with each other are mixed and then compacted at a pressure sufficient to reduce the space, volume between the particles of material, cause the reduced space volume to become filled with water and the reactive components to react.
    Type: Grant
    Filed: July 24, 1995
    Date of Patent: November 12, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Menzel, Joachim Beyer, Gerd Bauer, Bernd Koglin, Rolf Rink
  • Process for the preparation of cyanoimino-1,3-thiazolidines
    Patent number: 5574165
    Abstract: X is an acid radical, andA is a metal ion or an equivalent ammonium ion.
    Type: Grant
    Filed: July 26, 1995
    Date of Patent: November 12, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventor: Reinhard Lantzsch
  • Process for the preparation of 4,6-diaminoresorcinol
    Patent number: 5574188
    Abstract: 4,6-diaminoresorcinol can be prepared in a plurality of steps in such a way thata) 1,3-dichlorobenzene is nitrated with a mixed acid of HNO.sub.3, H.sub.2 SO.sub.4 and SO.sub.3 at 0 to 40.degree. C. in anhydrous H.sub.2 SO.sub.4,b) the resulting 1,3-dichloro-4,6/2,4-dinitrobenzene isomeric mixture is first reacted with benzyl alcohol in the presence of a strong base at -15.degree. C. to +15.degree. C. and then at 20.degree. to 40.degree. C. to give the dibenzyloxy compound andc) the 1,3-dibenzyloxy-4,6-dinitrobenzene isomer arising in pure form in b) is converted to the 4,6-diaminoresorcinol by catalytic hydrogenation.
    Type: Grant
    Filed: October 27, 1995
    Date of Patent: November 12, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Horst Behre, Helmut Fiege, Heinz-Ulrich Blank, Uwe Heinz, Wolfgang Eymann
  • Method for operating application software in a safety critical environment
    Patent number: 5572671
    Abstract: A method for operating application software in a safety critical environment, comprises loading application software into a computing system, linking the computing system to a set of safety critical rules to verify that the safety critical operations performed by the computing system satisfy rule criteria and running the application software in the computing system. Safety critical operations are performed as background functions during the running of the application software and if a failure to satisfy criteria for a safety critical operation is detected, the system determines the application specific operation being currently performed. The criteria, the action to be taken or both is dynamically adjusted if the currently performed application specific operation is critical operation.
    Type: Grant
    Filed: February 17, 1995
    Date of Patent: November 5, 1996
    Assignee: Base Ten Systems, Inc.
    Inventors: Alan J. Eisenberg, Alexander M. Adelson
  • CDNA coding for carcinoembryonic antigen
    Patent number: 5571710
    Abstract: A nucleic acid encoding a carcinoembryonic antigen (CEA) that cross-reacts with human CEA is described. In addition, vectors and host cells containing such nucleic acids are disclosed.
    Type: Grant
    Filed: December 20, 1993
    Date of Patent: November 5, 1996
    Assignee: Bayer Corporation
    Inventors: Thomas R. Barnett, James J. Elting, Michael E. Kamarck
  • Substituted (2-oxo-1-benzimidazolinyl)-peperidines, process for their preparation, and use as anti-retroviral agents
    Patent number: 5571921
    Abstract: The present invention relates to substituted (2-oxo-1-benzimidazolinyl)-piperidines of the general formula (I) ##STR1## in which the substituents have the meaning indicated in the description, to processes for their preparation and to their use as antiretroviral agents.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: November 5, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Bender, Dieter H abich, Siegfried Raddatz, Wolfgang R oben, Hanno Wild, Jutta Hansen, Arnold Paessens
  • Endoparasiticidal compositions based on open-chain tetradepsipeptides
    Patent number: 5571793
    Abstract: The present invention relates to the use of open-chain tetradepsipepties of the formula ##STR1## in a method for combatting endoparasites in humans and animals.
    Type: Grant
    Filed: December 2, 1994
    Date of Patent: November 5, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: J urgen Scherkenbeck, Peter Jeschke, Andrew Plant, Achim Harder, Norbert Mencke
  • Fused pyrimidine compounds and their use as pharmaceuticals
    Patent number: 5571813
    Abstract: Pharmaceutical compounds which are azolo-fused pyrimidine compounds having the formula ##STR1## in which .dbd.
    Type: Grant
    Filed: June 6, 1994
    Date of Patent: November 5, 1996
    Assignee: Beiersdorf-Lilly GmbH
    Inventors: Gerd R uhter, Theo Schotten, Wolfgang Stenzel, Michael Paal
  • 7-amino-1-cyclopropyl-6,8-dihalogeno- 1,4-dihydro-4-oxo-3-quinolinecarboxylic acid antibacterial agents
    Patent number: 5571812
    Abstract: The invention is related to 7-amino-1-cyclopropyl-6,8- dihalogeno-1,4-dihydro-4-oxo-3-quinoline-carboxylic acids of the formula (I) ##STR1## in which X.sup.1, X.sup.2, R.sup.1 and R.sup.2 have the meaning as pointed out in the following specification. Moreover, the invention is related to a process for the production of the compounds of formula (I) and to antibacterial agents containing them.
    Type: Grant
    Filed: April 27, 1992
    Date of Patent: November 5, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Uwe Petersen, Klaus Grohe, Hans-Joachim Zeiler, Karl G. Metzger
  • 4-amino-3-hydroxy-phthalimidine, and a process for the preparation thereof
    Patent number: 5571928
    Abstract: The present invention relates to 4-amino-3-hydroxy-phthalimidine, an important intermediate for the synthesis of 3-substituted 5-quinoline-carboxylic acid amides, and a process for the preparation thereof.
    Type: Grant
    Filed: July 19, 1995
    Date of Patent: November 5, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: J urgen Stoltefuss, Michael Negele, Friedrich D urholz
  • Intermediate for pesticidal aminomethylheterocyclic compounds
    Patent number: 5571930
    Abstract: Fungicidally active compounds of the formula ##STR1## in which X represents oxygen or sulphur,R represents cycloalkyl, or represents optionally substituted aryl, or represents the radical ##STR2## R.sup.1 and R.sup.2 each independently is hydrogen or an organic radical, or together with the nitrogen atom form a heterocyclic radical,R.sup.3 represents hydrogen, alkyl or optionally substituted aryl, andR.sup.4 represents alkyl or cycloalkyl, or represents optionally substituted aryl,but whereinR.sup.3 and R.sup.4 may not simultaneously represent methyl,and acid addition salts thereof, as well as intermediates therefor.
    Type: Grant
    Filed: September 26, 1995
    Date of Patent: November 5, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Kr amer, Joachim Weissm uller, Dieter Berg, Wilhelm Brandes, Stefan Dutzmann
  • 2-cyanobenzimidazoles and their use
    Patent number: 5571830
    Abstract: New 2-cyanobenzimidazoles of the formula (I) ##STR1## in which R.sup.1, R.sup.2 and A have the meaning given in the description, a preparation process, their use in agriculture, for example against fungi, insects etc., and new intermediates.Formula (I) provides a definition of the compounds; for example they are obtained from suitable 2-cyanobenzimidazoles which are unsubstituted in the 1-position with N,N-dimethylsulphamoyl halide. The 2-cyanobenzimidazoles which are unsubstituted in the 1-position are equally new and can be reacted from suitable phenylenediamines of the formula (IV) with methyl 2,2,2-trichloroacetimidate of the formula (V) to give the 2-trichloromethylbenzimidazoles of the formula (VI), which are equally new and from which the compounds of the formula (II) can subsequently be obtained with ammonia.
    Type: Grant
    Filed: January 16, 1996
    Date of Patent: November 5, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Winfried Lunkenheimer, Heinz-Wilheim Dehne, Ulrike Wachendorff-Neumann
  • Air flow meter with slide valve for milking machines
    Patent number: 5570870
    Abstract: An air-flow meter for milking machines, comprising an enclosed housing with a connection to a line that is to be tested for flow and pressure and with an air-intake mechanism with a variable cross-section. The air-intake mechanism is an air intake with a slot-shaped cross-section. A rotating cylinder is accommodated inside the housing and operates in conjunction with the slotted intake. The cylinder has a breach that tapers out along a considerable length of its circumference. The longitudinal axis of the intake parallels the axis the cylinder rotates around, the free cross-section of the intake is only a fraction of length of the breach along the circumference of the cylinder, and any area of the breach can be aligned with the air intake by rotating the cylinder.
    Type: Grant
    Filed: October 6, 1994
    Date of Patent: November 5, 1996
    Assignee: Westfalia Separator AG
    Inventor: Erwin Bilgery