Abstract: The invention provides styryl cyclopentenyl propanoic acids and derivatives thereof having spasmolytic activity coupled with low toxicity. Also provided is a method of preparing styryl cyclopentenyl propanoic acid compounds which involves cyclising 7-hydroxy-5,8-dioxo-10-phenyldec-9-enoic acid in the presence of a base.
Type:
Grant
Filed:
April 10, 1974
Date of Patent:
December 28, 1976
Assignee:
Lilly Industries, Ltd.
Inventors:
William Dawson, Michael John Foulis, Norman James Albert Gutteridge, Colin William Smith