Patents Represented by Attorney, Agent or Law Firm Steven P. Lendaris
  • Simultaneous screening and identification of sequence alterations from amplified target
    Patent number: 6753141
    Abstract: Methods for identifying and locating alterations in a nucleic acid having a known sequence are provided. The methods involve measuring the melting temperature of probe nucleic acids hybridized to a target nucleic acid. The methods take advantage of the differential dissociation temperatures of a probe from a target resulting from mismatches at different locations along the region of the target to which the probe hybridizes.
    Type: Grant
    Filed: January 25, 2001
    Date of Patent: June 22, 2004
    Assignee: The University of Utah
    Inventors: Philip S. Bernard, Carl T. Wittwer, Gregory Pritham