Abstract: Compositions comprising keratinocyte growth factor (KGF) polypeptides and methods of using the same are described. The KGF polypeptides of the present invention display enhanced bioactivity relative to full-length KGF163. Accordingly, the KGF polypeptides of the present invention may be used in compositions in lesser amounts than would be necessary using KGF163.
Type:
Grant
Filed:
August 21, 2002
Date of Patent:
September 4, 2007
Assignee:
Chiron Corporation
Inventors:
Denis J. Gospodarowicz, W. Michael Kavanaugh, Kenneth Crawford