Patents Represented by Attorney, Agent or Law Firm Susan Petraglia
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Patent number: 7207140Abstract: The invention provides a new form of vegetative propagating material, referred to as “the grass plantlet”, as well as a method for producing it. The new vegetative planting material and the method by which it is obtained make it possible to replicate and increase both warm and cool season grasses more rapidly than by the conventional methods of seeding, sprigging, or plugging. Three to five new, clean, and pure generations of a newly developed seeded or vegetative cultivar can be obtained each year. Outcrossing, the need for burning and possibly for herbicide use are eliminated by the present invention. The present methodology embodies a sterile production system resulting in grass plantlets that are free of nematodes, pathogenic fungi, and damaging insects.Type: GrantFiled: December 29, 2003Date of Patent: April 24, 2007Assignee: Buckeye Bluegrass Farms, Inc.Inventor: Henry F. Decker
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Patent number: 6342468Abstract: The invention relates to compositions and methods for gelling liquid hydrocarbons by the introduction of certain phosphate esters, a crosslinking agent, and an enhancer. The enhancer of the present invention is preferably an oxyalkylated amine or a blend of an oxyalkylated amine with another amine or a non-nitrogen-containing component. Mixed phosphate esters containing an oxyalkylene group are useful in the practice of the invention. Gel-forming compositions for addition to liquid hydrocarbons, as well as methods for forming fracturing fluids, are encompassed. The present compositions and methods are an improvement in the field of hydrocarbon gelling, e.g., in fracturing formations, by providing more rapid gellation and greater viscosities.Type: GrantFiled: May 15, 2000Date of Patent: January 29, 2002Assignee: Ethox Chemicals LLCInventor: George Gregory Geib
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Patent number: 6329414Abstract: Nutriceutical compositions useful as a dietary supplement which have antioxidant/free radical scavengers and also having a cytoprotective effect are disclosed. The compositions contain a cytoprotective and antioxidant/free radical scavenging amount of at least one of D-histidine, L-histidine, a racemic mixture thereof, a non-racemic mixture thereof, and nutriceutically acceptable salts thereof in combination with phytonutrients having antioxidant properties such as canthanaxin, vitamin A and limonene. The compositions can be prepared in capsule form, tablets, sustained release tablets, suspensions and oral rehydration solutions.Type: GrantFiled: September 10, 1999Date of Patent: December 11, 2001Assignee: Cytos Pharmaceuticals LLCInventors: Peter G. Thomas, A. Michael Wade
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Patent number: 6286253Abstract: A method for planting and stabilizing soilless sods is taught, beginning with planting pure stock of the desired cultivar in sterile media over plastic sheeting. The pure stock, once it has matured into a sod, it is harvested and milled into vegetative planting material. The milled material is suspended in a liquid slurry in an agitating tank and discharged into a trailing planter assembly that spreads the slurry evenly over unrolling plastic sheeting where it acts not only as planting material but, in sufficient quantities, also as a stabilizing protective mulch that maintains the integrity of the young sod crop in severe storms. Unlike sprigs or stolons the milled planting stock is produced from whole plant tissue and is comprised of many plantlets with intact root, stem, and leaf tissue. A bushel of milled turf plantlets is much more dense than a bushel of sprigs or stolons and comprises meristems from all parts of the plant including roots, crowns, and rhizomes.Type: GrantFiled: June 18, 1999Date of Patent: September 11, 2001Assignee: Buckeye Bluegrass Farms, IncInventor: Henry F. Decker
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Patent number: 6211221Abstract: The present invention relates to methods for alleviating disorders or chronic conditions of the female reproductive system, such as dysmenorrhea, endometrial pain, and pre-term labor, through dietary supplementation with histidine. The invention relates further to novel combination supplements of histidine in conjunction with other nutritional supplement materials which are preferably also useful in alleviating the above-mentioned disorders or conditions. A method for administering a dietary histidine supplement in conjunction with one or more separately formulated therapeutic drugs also known to be useful in treating these female reproductive conditions is also disclosed.Type: GrantFiled: April 5, 1999Date of Patent: April 3, 2001Inventors: Johnny W. Peterson, Peter G. Thomas
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Patent number: 6207696Abstract: The present invention relates to methods and compositions for preventing or treating conditions or disorders of the female reproductive system by administering an effective dosage of histidine alone or in combination with other therapeutic agents. The invention relates also to novel physical compositions and delivery devices for administering histidine effectively to a female subject in need of either prophylaxis or treatment of certain disorders of the reproductive system.Type: GrantFiled: September 15, 1998Date of Patent: March 27, 2001Assignee: Cytos Pharamaceuticals, LLCInventors: John Peterson, Peter G. Thomas
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Patent number: 6150392Abstract: The administration of histidine is able to prevent and ameliorate tissue and cellular damage which is caused by damaging levels of cytokines and growth factors. It is shown that histidine, when administered in therapeutic quantities is able to inhibit cytokines and growth factors involved in cell and tissue damage. In addition, the method of adminstering histidine to inhibit these molecules can prevent and ameliorate tissue, vessel and cell damage from restenosis, burns, surgical procedures and other disorders which cause and result from damaged tissues, vessels and cells.Type: GrantFiled: December 24, 1998Date of Patent: November 21, 2000Inventors: Peter G. Thomas, Jose-Luis Diaz
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Patent number: 6136200Abstract: A composition for the detackification and clarification of acid and alkaline paint and lacquer waste waters and paint spray booth wastes, comprising:an inorganic-organic and/or organic adduct alloy polymer composition having the formula:A.multidot.B.sup.+ .multidot.D.sup.+wherein: A=[(SiO.sub.2 /Me.sup.I.sub.2 O).sub.u Me.sup.II.sub.m Me.sub.m.sup.III(OH).sbsp.p.sup.(SO.sbsp.4.sup.).sbsp.y.sup.(Aci) (2m+3n)-p-2y].sub.rwhere r=1 to 98% bw; u=0 to 10% bw; ##STR1## where: x=0 to 98% bw; Z is a divalent substituted or unsubstituted aliphatic, cycloaliphatic, heterocyclic or aromatic radicalD.sup.+ =(PQAM).sub.wwherew=2 to 98% b.w. of polyquaternized polymer (PQAM)Me.sub.m.sup.II is selected from the divalent cationic group comprising: Mg, Zn, Ca, and Fe.sup.2+m=0 to 5Me.sub.n.sup.III is a tri-or more valent metal selected from the group comprising: Fe, Al, and Al--Zn complexes;n=1 to 20Aci is selected from the monovalent anionic group comprising Cl.sup.-, Br.sup.-, I.sup.-, NO.sub.3 --, H.sub.2 PO.sub.4 --, CH.Type: GrantFiled: March 11, 1994Date of Patent: October 24, 2000Assignee: Polymer Research CorporationInventor: John J. Waldmann
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Patent number: 5899020Abstract: A novel method is proposed for the vegetative propagation of grasses and some dicots comprised first of growing sods of the desired cultivar over plastic sheeting in a sterile medium. When the planting has matured into a sod, it is harvested in strips which are milled and screened into milled turf pieces or plantlets that are approximately 1 to 3 inches long. In comparison to a sprig or stolon, a milled turf piece or plantlet is produced from a complete piece of sod grown over plastic in which the complete root system has been contained. The milled turf product includes plantlets with complete root, stem and leaf tissue all ready to grow. Bushel for bushel, the milled turf product is more dense with more growing points or meristems and per area it provides quicker grow-in.Type: GrantFiled: May 12, 1997Date of Patent: May 4, 1999Inventor: Henry F. Decker
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Patent number: 5710172Abstract: Histidine has been found to be efficacious in preventing ischemic/reperfusion induced myocardial injury both functionally and ultrastructurally. Isolated perfused rat hearts (n=8/group) were subjected to 30 minutes of global ischemia and 20 minutes of reperfusion. Histidine concentrations ranging from 10 to 50 mM were given throughout the experiment. During ischemia and reperfusion without histidine the contractile function and coronary flow were 59.+-.10% and 78.+-.6% of control, respectively. Perfusion with histidine (25 mM and above) resulted in significant increases in contractility (94.+-.4%) and coronary flow (92.+-.4) levels. The incidence of arrhythmias (ventricular tachycardia and ventricular fibrillation) during reperfusion was 100 percent (8/8) in the ischemic/reperfused group with an average duration of 13.23.+-.4.48 min. The addition of 25 mM histidine to the perfusion medium reduced the incidence and duration of arrhythmias significantly (mean.+-.SEM 2.25.+-.0.98 min) (P<0.01).Type: GrantFiled: June 7, 1995Date of Patent: January 20, 1998Assignee: CYTOS Pharmaceuticals, LLCInventors: Rakesh C. Kukreja, Michael L. Hess
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Patent number: 5658937Abstract: A treatment modality for infectious diseases and pulmonary conditions that result from the inflammatory responses by tissues to infections by microorganisms, including but not limited to viruses, retroviruses, bacteria, or other microorganisms, or toxins that arise from microorganisms comprises administering an effective amount of histidine to the affected subject to combat the disease or the distress condition resulting therefrom.Type: GrantFiled: September 30, 1994Date of Patent: August 19, 1997Assignee: Cytos Pharmaceuticals LLCInventor: Peter G. Thomas
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Patent number: 5525621Abstract: Compounds of the formula ##STR1## wherein the substituents are as defined in the disclosure. The compounds are particularly useful for inhibiting damage to a variety of mammalian tissue that are jeopardized, for example, during runaway inflammatory conditions due to the damaging presence of singlet oxygen, the hydroxyl radical, cytokines and growth factors. The compounds are also useful in inhibiting damage to cardiac and central nervous system tissues during reperfusion.Type: GrantFiled: May 20, 1994Date of Patent: June 11, 1996Assignee: Cytos Pharmaceuticals LLCInventors: Stanley Burt, Jack R. Collins