Patents Represented by Attorney, Agent or Law Firm Susan Petraglia
  • Patent number: 7207140
    Abstract: The invention provides a new form of vegetative propagating material, referred to as “the grass plantlet”, as well as a method for producing it. The new vegetative planting material and the method by which it is obtained make it possible to replicate and increase both warm and cool season grasses more rapidly than by the conventional methods of seeding, sprigging, or plugging. Three to five new, clean, and pure generations of a newly developed seeded or vegetative cultivar can be obtained each year. Outcrossing, the need for burning and possibly for herbicide use are eliminated by the present invention. The present methodology embodies a sterile production system resulting in grass plantlets that are free of nematodes, pathogenic fungi, and damaging insects.
    Type: Grant
    Filed: December 29, 2003
    Date of Patent: April 24, 2007
    Assignee: Buckeye Bluegrass Farms, Inc.
    Inventor: Henry F. Decker
  • Patent number: 6342468
    Abstract: The invention relates to compositions and methods for gelling liquid hydrocarbons by the introduction of certain phosphate esters, a crosslinking agent, and an enhancer. The enhancer of the present invention is preferably an oxyalkylated amine or a blend of an oxyalkylated amine with another amine or a non-nitrogen-containing component. Mixed phosphate esters containing an oxyalkylene group are useful in the practice of the invention. Gel-forming compositions for addition to liquid hydrocarbons, as well as methods for forming fracturing fluids, are encompassed. The present compositions and methods are an improvement in the field of hydrocarbon gelling, e.g., in fracturing formations, by providing more rapid gellation and greater viscosities.
    Type: Grant
    Filed: May 15, 2000
    Date of Patent: January 29, 2002
    Assignee: Ethox Chemicals LLC
    Inventor: George Gregory Geib
  • Patent number: 6329414
    Abstract: Nutriceutical compositions useful as a dietary supplement which have antioxidant/free radical scavengers and also having a cytoprotective effect are disclosed. The compositions contain a cytoprotective and antioxidant/free radical scavenging amount of at least one of D-histidine, L-histidine, a racemic mixture thereof, a non-racemic mixture thereof, and nutriceutically acceptable salts thereof in combination with phytonutrients having antioxidant properties such as canthanaxin, vitamin A and limonene. The compositions can be prepared in capsule form, tablets, sustained release tablets, suspensions and oral rehydration solutions.
    Type: Grant
    Filed: September 10, 1999
    Date of Patent: December 11, 2001
    Assignee: Cytos Pharmaceuticals LLC
    Inventors: Peter G. Thomas, A. Michael Wade
  • Patent number: 6286253
    Abstract: A method for planting and stabilizing soilless sods is taught, beginning with planting pure stock of the desired cultivar in sterile media over plastic sheeting. The pure stock, once it has matured into a sod, it is harvested and milled into vegetative planting material. The milled material is suspended in a liquid slurry in an agitating tank and discharged into a trailing planter assembly that spreads the slurry evenly over unrolling plastic sheeting where it acts not only as planting material but, in sufficient quantities, also as a stabilizing protective mulch that maintains the integrity of the young sod crop in severe storms. Unlike sprigs or stolons the milled planting stock is produced from whole plant tissue and is comprised of many plantlets with intact root, stem, and leaf tissue. A bushel of milled turf plantlets is much more dense than a bushel of sprigs or stolons and comprises meristems from all parts of the plant including roots, crowns, and rhizomes.
    Type: Grant
    Filed: June 18, 1999
    Date of Patent: September 11, 2001
    Assignee: Buckeye Bluegrass Farms, Inc
    Inventor: Henry F. Decker
  • Patent number: 6211221
    Abstract: The present invention relates to methods for alleviating disorders or chronic conditions of the female reproductive system, such as dysmenorrhea, endometrial pain, and pre-term labor, through dietary supplementation with histidine. The invention relates further to novel combination supplements of histidine in conjunction with other nutritional supplement materials which are preferably also useful in alleviating the above-mentioned disorders or conditions. A method for administering a dietary histidine supplement in conjunction with one or more separately formulated therapeutic drugs also known to be useful in treating these female reproductive conditions is also disclosed.
    Type: Grant
    Filed: April 5, 1999
    Date of Patent: April 3, 2001
    Inventors: Johnny W. Peterson, Peter G. Thomas
  • Patent number: 6207696
    Abstract: The present invention relates to methods and compositions for preventing or treating conditions or disorders of the female reproductive system by administering an effective dosage of histidine alone or in combination with other therapeutic agents. The invention relates also to novel physical compositions and delivery devices for administering histidine effectively to a female subject in need of either prophylaxis or treatment of certain disorders of the reproductive system.
    Type: Grant
    Filed: September 15, 1998
    Date of Patent: March 27, 2001
    Assignee: Cytos Pharamaceuticals, LLC
    Inventors: John Peterson, Peter G. Thomas
  • Patent number: 6150392
    Abstract: The administration of histidine is able to prevent and ameliorate tissue and cellular damage which is caused by damaging levels of cytokines and growth factors. It is shown that histidine, when administered in therapeutic quantities is able to inhibit cytokines and growth factors involved in cell and tissue damage. In addition, the method of adminstering histidine to inhibit these molecules can prevent and ameliorate tissue, vessel and cell damage from restenosis, burns, surgical procedures and other disorders which cause and result from damaged tissues, vessels and cells.
    Type: Grant
    Filed: December 24, 1998
    Date of Patent: November 21, 2000
    Inventors: Peter G. Thomas, Jose-Luis Diaz
  • Patent number: 6136200
    Abstract: A composition for the detackification and clarification of acid and alkaline paint and lacquer waste waters and paint spray booth wastes, comprising:an inorganic-organic and/or organic adduct alloy polymer composition having the formula:A.multidot.B.sup.+ .multidot.D.sup.+wherein: A=[(SiO.sub.2 /Me.sup.I.sub.2 O).sub.u Me.sup.II.sub.m Me.sub.m.sup.III(OH).sbsp.p.sup.(SO.sbsp.4.sup.).sbsp.y.sup.(Aci) (2m+3n)-p-2y].sub.rwhere r=1 to 98% bw; u=0 to 10% bw; ##STR1## where: x=0 to 98% bw; Z is a divalent substituted or unsubstituted aliphatic, cycloaliphatic, heterocyclic or aromatic radicalD.sup.+ =(PQAM).sub.wwherew=2 to 98% b.w. of polyquaternized polymer (PQAM)Me.sub.m.sup.II is selected from the divalent cationic group comprising: Mg, Zn, Ca, and Fe.sup.2+m=0 to 5Me.sub.n.sup.III is a tri-or more valent metal selected from the group comprising: Fe, Al, and Al--Zn complexes;n=1 to 20Aci is selected from the monovalent anionic group comprising Cl.sup.-, Br.sup.-, I.sup.-, NO.sub.3 --, H.sub.2 PO.sub.4 --, CH.
    Type: Grant
    Filed: March 11, 1994
    Date of Patent: October 24, 2000
    Assignee: Polymer Research Corporation
    Inventor: John J. Waldmann
  • Patent number: 5899020
    Abstract: A novel method is proposed for the vegetative propagation of grasses and some dicots comprised first of growing sods of the desired cultivar over plastic sheeting in a sterile medium. When the planting has matured into a sod, it is harvested in strips which are milled and screened into milled turf pieces or plantlets that are approximately 1 to 3 inches long. In comparison to a sprig or stolon, a milled turf piece or plantlet is produced from a complete piece of sod grown over plastic in which the complete root system has been contained. The milled turf product includes plantlets with complete root, stem and leaf tissue all ready to grow. Bushel for bushel, the milled turf product is more dense with more growing points or meristems and per area it provides quicker grow-in.
    Type: Grant
    Filed: May 12, 1997
    Date of Patent: May 4, 1999
    Inventor: Henry F. Decker
  • Patent number: 5710172
    Abstract: Histidine has been found to be efficacious in preventing ischemic/reperfusion induced myocardial injury both functionally and ultrastructurally. Isolated perfused rat hearts (n=8/group) were subjected to 30 minutes of global ischemia and 20 minutes of reperfusion. Histidine concentrations ranging from 10 to 50 mM were given throughout the experiment. During ischemia and reperfusion without histidine the contractile function and coronary flow were 59.+-.10% and 78.+-.6% of control, respectively. Perfusion with histidine (25 mM and above) resulted in significant increases in contractility (94.+-.4%) and coronary flow (92.+-.4) levels. The incidence of arrhythmias (ventricular tachycardia and ventricular fibrillation) during reperfusion was 100 percent (8/8) in the ischemic/reperfused group with an average duration of 13.23.+-.4.48 min. The addition of 25 mM histidine to the perfusion medium reduced the incidence and duration of arrhythmias significantly (mean.+-.SEM 2.25.+-.0.98 min) (P<0.01).
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 20, 1998
    Assignee: CYTOS Pharmaceuticals, LLC
    Inventors: Rakesh C. Kukreja, Michael L. Hess
  • Patent number: 5658937
    Abstract: A treatment modality for infectious diseases and pulmonary conditions that result from the inflammatory responses by tissues to infections by microorganisms, including but not limited to viruses, retroviruses, bacteria, or other microorganisms, or toxins that arise from microorganisms comprises administering an effective amount of histidine to the affected subject to combat the disease or the distress condition resulting therefrom.
    Type: Grant
    Filed: September 30, 1994
    Date of Patent: August 19, 1997
    Assignee: Cytos Pharmaceuticals LLC
    Inventor: Peter G. Thomas
  • Patent number: 5525621
    Abstract: Compounds of the formula ##STR1## wherein the substituents are as defined in the disclosure. The compounds are particularly useful for inhibiting damage to a variety of mammalian tissue that are jeopardized, for example, during runaway inflammatory conditions due to the damaging presence of singlet oxygen, the hydroxyl radical, cytokines and growth factors. The compounds are also useful in inhibiting damage to cardiac and central nervous system tissues during reperfusion.
    Type: Grant
    Filed: May 20, 1994
    Date of Patent: June 11, 1996
    Assignee: Cytos Pharmaceuticals LLC
    Inventors: Stanley Burt, Jack R. Collins