Abstract: A method is provided for inactivating viral and/or bacterial contamination in blood cellular matter, such as erythrocytes and platelets, or protein fractions. The cells or protein fractions are mixed with chemical sensitizers and irradiated with, for example, UV, visible, gamma or X-ray radiation. In particular, quaternary ammonium or phosphonium substituted, halo-psoralen compounds are described as being useful.
Type:
Grant
Filed:
July 13, 1993
Date of Patent:
May 23, 1995
Assignee:
Cryopharm Corporation
Inventors:
Matthew S. Platz, Raymond P. Goodrich, Jr., Nagendar Yerram