Patents Represented by Attorney T. D. Brainard
  • Patent number: 5804234
    Abstract: The present invention relates generally to a method of producing plant proteins for use in nutritional products that have reduced levels of phytoestrogens, manganese or nucleotides. More specifically, this invention is directed to a method of using ion exchange technology to remove phytoestrogens, manganese or nucleotides from plant proteins. This invention is also directed to the plant protein product resulting from the inventive process and to nutritional products that use the plant protein product as a source of amino nitrogen.
    Type: Grant
    Filed: September 13, 1996
    Date of Patent: September 8, 1998
    Inventors: John D. Suh, Karin M. Ostrom, Louis I. Ndife, Paul S. Anloague, James N. Chmura, Andre Daab-Krzykowski, Paul W. Johns, Diane M. Garcia, Terrence B. Mazer, Fu-I Mei
  • Patent number: 5700777
    Abstract: This invention discloses a method for chemically modifying a pulmonary surfactant protein or polypeptides with various fatty acids. These conjugates are useful in preparing formulations for the treatment of respiratory disease.
    Type: Grant
    Filed: April 24, 1995
    Date of Patent: December 23, 1997
    Assignee: Abbott Laboratories
    Inventors: Virender Kumar Sarin, Darryl Robin Absolom, Shanker Lal Gupta
  • Patent number: 5661180
    Abstract: There is disclosed structured lipid containing either a gamma-linolenic acid or a dihomogamma-linolenic acid residue, together with an n-3 fatty acid residue and a medium chain fatty acid residue on the same glycerol backbone. This structured lipid is particularly well adapted to the treatment of disease or stress states. The gamma-linolenic or dihomogamma-linolenic acid residues modify the prostanoid synthesis pathway, reducing the level of series "2" prostanoids and elevating the levels of series "1" and "3" prostanoids. The n-3 fatty acid residue enhances the level of series "1" prostanoids as well as increases the production of series "3" prostanoids. The medium chain fatty acid residues enhances the absorption of the structured lipid. There is also disclosed enteral and parenteral diets as well as nutritional supplements containing the structured lipids of the invention.
    Type: Grant
    Filed: March 30, 1995
    Date of Patent: August 26, 1997
    Assignees: Abbott Laboratories, New England Deaconess Hospital, University of Tennessee Research Corporation
    Inventors: Stephen Joseph DeMichele, Michael Donald Karlstad, Bruce Ryan Bistrian, Edward Anthony Mascioli
  • Patent number: 5658893
    Abstract: A method is provided for inhibiting rotavirus infection of human cells by treating the rotavirus with a carrageenan. The most effective agent in inhibiting cellular rotavirus infection is lambda-carrageenan, which may be formulated in a liquid and ingested enterally. A composition containing lambda-carrageenan is an aspect of the invention.
    Type: Grant
    Filed: March 29, 1995
    Date of Patent: August 19, 1997
    Assignee: Abbott Laboratories
    Inventors: Steven Neal Anderson, Joseph Paul Schaller, Terrence Bruce Mazer, Stephen John Kirchner
  • Patent number: 5641531
    Abstract: A protein containing nutritional supplement that contains from 1 to 10% by weight of whey protein isolate, at least one source of carbohydrate, vitamins, trace minerals and ultra trace minerals and ultra trace minerals. The pH of the liquid nutritional supplement is from about 2.8 to about 3.3 and is essentially devoid of added macro-nutrients and fat. A supplement which is clear and low in viscosity, is produced by preparing (1) an acidified aqueous solution of whey protein isolate having a pH of about 2.8 to about 3.3 and (2) an aqueous solution of carbohydrate; and thereafter combining the two solutions.
    Type: Grant
    Filed: September 28, 1995
    Date of Patent: June 24, 1997
    Assignee: Abbott Laboratories
    Inventors: Jeffery Wayne Liebrecht, Terrence Bruce Mazer, Michael Allen Chandler, Gerald Edward Schopinsky, Normanella Torres Dewille
  • Patent number: 5609909
    Abstract: Prolamine fractions of grain proteins, applied as a single coating in weight ratios of 5 to 100% relative to the active substance being coated, result in the production of a liquid suspension which effectively masks the taste of orally administered drugs which often are extremely bitter. The taste masking is stable over prolonged periods of storage time of the suspension. The prolamine coating does not restrict the immediate bioavailability of the active substance. Prolamine coating is effective in masking the taste of antibiotics, vitamins, dietary fiber, analgesics, enzymes and hormones. Zein, gliadin or a mixture thereof, particularly in combination with between 2.
    Type: Grant
    Filed: April 13, 1995
    Date of Patent: March 11, 1997
    Assignee: Abbott Laboratories
    Inventors: Glenn A. Meyer, Terrence B. Mazer
  • Patent number: 5609897
    Abstract: A powdered beverage concentrate contains a source of calcium, vitamin D, a stabilizing gum such as gum arabic, and vegetable oil. A beverage can be made by reconstituting the beverage concentrate with water, fruit juice, or any other suitable liquid matrix.
    Type: Grant
    Filed: April 7, 1995
    Date of Patent: March 11, 1997
    Assignee: Abbott Laboratories
    Inventors: Michael A. Chandler, Normanella T. DeWille, Terrence B. Mazer, Robert J. Ragan, Gregory A. Snowden, Maureen E. Geraghty, Catherine D. Johnson, Lonnie R. Drayer
  • Patent number: 5602109
    Abstract: An improved enteral nutritional formula containing ribo-nucleotide equivalents (RNA, mono-, di- and triphosphate nucleotides, nucleosides and adjuncts such as activated sugars) at a level of at least 10 mg/100 Kcal (kilocalorie) of formula is disclosed. The formula comprises carbohydrates, lipids, proteins, vitamins and minerals and four (4) ribo-nucleotide equivalents at specific levels and ratios. The invention also discloses novel methods of production and analytical techniques. This invention also provides a dietary formula that enhances the immune system and alleviates diarrhea.
    Type: Grant
    Filed: January 10, 1994
    Date of Patent: February 11, 1997
    Assignee: Abbott Laboratories
    Inventors: Marc L. Masor, Milo D. Hilty
  • Patent number: 5599556
    Abstract: Prolamine fractions of grain proteins, applied as a single coating in weight ratios of 5 to 100% relative to the active substance being coated, result in the production of a liquid suspension which effectively masks the taste of orally administered drugs which often are extremely bitter. The taste masking is stable over prolonged periods of storage time of the suspension. The prolamine coating does not restrict the immediate bioavailability of the active substance. Prolamine coating is effective in masking the taste of antibiotics, vitamins, dietary fiber, analgesics, enzymes and hormones. Zein, gliadin or a mixture thereof, particularly in combination with between 2.
    Type: Grant
    Filed: May 19, 1994
    Date of Patent: February 4, 1997
    Assignee: Abbott Laboratories
    Inventors: Glenn A. Meyer, Terrence B. Mazer
  • Patent number: 5554589
    Abstract: Fish oil is stored refrigerated under a nitrogen blanket until it is added to an enteral nutritional product during product manufacture. While the nutritional product is passing through a conduit the fish oil is added to the product at a uniform ratio such that the fish oil is evenly disbursed throughout the product, and thereafter the product is homogenized and heat treated.
    Type: Grant
    Filed: October 12, 1994
    Date of Patent: September 10, 1996
    Assignee: Abbott Laboratories
    Inventors: Normanella T. Dewille, Terrence B. Mazer, Edward H. Parke, Francis J. Cipriano, Dennis L. Raube
  • Patent number: 5550146
    Abstract: The present invention relates generally to a generic powder base rich in fats, carbohydrates, vitamins and minerals and trace elements which can be readily admixed with specific amino acids to yield several different therapeutic products for use in the nutritional support of various inherited metabolic diseases.
    Type: Grant
    Filed: April 18, 1995
    Date of Patent: August 27, 1996
    Assignee: Abbott Laboratories
    Inventors: Phyllis J. B. Acosta, Richard A. Grondalski, Jeffrey W. Liebrecht, Patricia A. Reynolds