Patents Represented by Attorney T. D. Brainard
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Patent number: 5804234Abstract: The present invention relates generally to a method of producing plant proteins for use in nutritional products that have reduced levels of phytoestrogens, manganese or nucleotides. More specifically, this invention is directed to a method of using ion exchange technology to remove phytoestrogens, manganese or nucleotides from plant proteins. This invention is also directed to the plant protein product resulting from the inventive process and to nutritional products that use the plant protein product as a source of amino nitrogen.Type: GrantFiled: September 13, 1996Date of Patent: September 8, 1998Inventors: John D. Suh, Karin M. Ostrom, Louis I. Ndife, Paul S. Anloague, James N. Chmura, Andre Daab-Krzykowski, Paul W. Johns, Diane M. Garcia, Terrence B. Mazer, Fu-I Mei
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Patent number: 5700777Abstract: This invention discloses a method for chemically modifying a pulmonary surfactant protein or polypeptides with various fatty acids. These conjugates are useful in preparing formulations for the treatment of respiratory disease.Type: GrantFiled: April 24, 1995Date of Patent: December 23, 1997Assignee: Abbott LaboratoriesInventors: Virender Kumar Sarin, Darryl Robin Absolom, Shanker Lal Gupta
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Patent number: 5661180Abstract: There is disclosed structured lipid containing either a gamma-linolenic acid or a dihomogamma-linolenic acid residue, together with an n-3 fatty acid residue and a medium chain fatty acid residue on the same glycerol backbone. This structured lipid is particularly well adapted to the treatment of disease or stress states. The gamma-linolenic or dihomogamma-linolenic acid residues modify the prostanoid synthesis pathway, reducing the level of series "2" prostanoids and elevating the levels of series "1" and "3" prostanoids. The n-3 fatty acid residue enhances the level of series "1" prostanoids as well as increases the production of series "3" prostanoids. The medium chain fatty acid residues enhances the absorption of the structured lipid. There is also disclosed enteral and parenteral diets as well as nutritional supplements containing the structured lipids of the invention.Type: GrantFiled: March 30, 1995Date of Patent: August 26, 1997Assignees: Abbott Laboratories, New England Deaconess Hospital, University of Tennessee Research CorporationInventors: Stephen Joseph DeMichele, Michael Donald Karlstad, Bruce Ryan Bistrian, Edward Anthony Mascioli
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Patent number: 5658893Abstract: A method is provided for inhibiting rotavirus infection of human cells by treating the rotavirus with a carrageenan. The most effective agent in inhibiting cellular rotavirus infection is lambda-carrageenan, which may be formulated in a liquid and ingested enterally. A composition containing lambda-carrageenan is an aspect of the invention.Type: GrantFiled: March 29, 1995Date of Patent: August 19, 1997Assignee: Abbott LaboratoriesInventors: Steven Neal Anderson, Joseph Paul Schaller, Terrence Bruce Mazer, Stephen John Kirchner
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Patent number: 5641531Abstract: A protein containing nutritional supplement that contains from 1 to 10% by weight of whey protein isolate, at least one source of carbohydrate, vitamins, trace minerals and ultra trace minerals and ultra trace minerals. The pH of the liquid nutritional supplement is from about 2.8 to about 3.3 and is essentially devoid of added macro-nutrients and fat. A supplement which is clear and low in viscosity, is produced by preparing (1) an acidified aqueous solution of whey protein isolate having a pH of about 2.8 to about 3.3 and (2) an aqueous solution of carbohydrate; and thereafter combining the two solutions.Type: GrantFiled: September 28, 1995Date of Patent: June 24, 1997Assignee: Abbott LaboratoriesInventors: Jeffery Wayne Liebrecht, Terrence Bruce Mazer, Michael Allen Chandler, Gerald Edward Schopinsky, Normanella Torres Dewille
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Patent number: 5609909Abstract: Prolamine fractions of grain proteins, applied as a single coating in weight ratios of 5 to 100% relative to the active substance being coated, result in the production of a liquid suspension which effectively masks the taste of orally administered drugs which often are extremely bitter. The taste masking is stable over prolonged periods of storage time of the suspension. The prolamine coating does not restrict the immediate bioavailability of the active substance. Prolamine coating is effective in masking the taste of antibiotics, vitamins, dietary fiber, analgesics, enzymes and hormones. Zein, gliadin or a mixture thereof, particularly in combination with between 2.Type: GrantFiled: April 13, 1995Date of Patent: March 11, 1997Assignee: Abbott LaboratoriesInventors: Glenn A. Meyer, Terrence B. Mazer
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Patent number: 5609897Abstract: A powdered beverage concentrate contains a source of calcium, vitamin D, a stabilizing gum such as gum arabic, and vegetable oil. A beverage can be made by reconstituting the beverage concentrate with water, fruit juice, or any other suitable liquid matrix.Type: GrantFiled: April 7, 1995Date of Patent: March 11, 1997Assignee: Abbott LaboratoriesInventors: Michael A. Chandler, Normanella T. DeWille, Terrence B. Mazer, Robert J. Ragan, Gregory A. Snowden, Maureen E. Geraghty, Catherine D. Johnson, Lonnie R. Drayer
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Patent number: 5602109Abstract: An improved enteral nutritional formula containing ribo-nucleotide equivalents (RNA, mono-, di- and triphosphate nucleotides, nucleosides and adjuncts such as activated sugars) at a level of at least 10 mg/100 Kcal (kilocalorie) of formula is disclosed. The formula comprises carbohydrates, lipids, proteins, vitamins and minerals and four (4) ribo-nucleotide equivalents at specific levels and ratios. The invention also discloses novel methods of production and analytical techniques. This invention also provides a dietary formula that enhances the immune system and alleviates diarrhea.Type: GrantFiled: January 10, 1994Date of Patent: February 11, 1997Assignee: Abbott LaboratoriesInventors: Marc L. Masor, Milo D. Hilty
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Patent number: 5599556Abstract: Prolamine fractions of grain proteins, applied as a single coating in weight ratios of 5 to 100% relative to the active substance being coated, result in the production of a liquid suspension which effectively masks the taste of orally administered drugs which often are extremely bitter. The taste masking is stable over prolonged periods of storage time of the suspension. The prolamine coating does not restrict the immediate bioavailability of the active substance. Prolamine coating is effective in masking the taste of antibiotics, vitamins, dietary fiber, analgesics, enzymes and hormones. Zein, gliadin or a mixture thereof, particularly in combination with between 2.Type: GrantFiled: May 19, 1994Date of Patent: February 4, 1997Assignee: Abbott LaboratoriesInventors: Glenn A. Meyer, Terrence B. Mazer
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Patent number: 5554589Abstract: Fish oil is stored refrigerated under a nitrogen blanket until it is added to an enteral nutritional product during product manufacture. While the nutritional product is passing through a conduit the fish oil is added to the product at a uniform ratio such that the fish oil is evenly disbursed throughout the product, and thereafter the product is homogenized and heat treated.Type: GrantFiled: October 12, 1994Date of Patent: September 10, 1996Assignee: Abbott LaboratoriesInventors: Normanella T. Dewille, Terrence B. Mazer, Edward H. Parke, Francis J. Cipriano, Dennis L. Raube
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Patent number: 5550146Abstract: The present invention relates generally to a generic powder base rich in fats, carbohydrates, vitamins and minerals and trace elements which can be readily admixed with specific amino acids to yield several different therapeutic products for use in the nutritional support of various inherited metabolic diseases.Type: GrantFiled: April 18, 1995Date of Patent: August 27, 1996Assignee: Abbott LaboratoriesInventors: Phyllis J. B. Acosta, Richard A. Grondalski, Jeffrey W. Liebrecht, Patricia A. Reynolds