Patents Represented by Law Firm Tarolli, Sundheim & Covell
  • Patent number: 8349581
    Abstract: Methods for characterizing the near term risk of experiencing a major adverse cardiac event in a patient presenting with chest pain are provided. In one embodiment the method comprises determining the level of myeloperoxidase (MPO) activity in a bodily sample obtained from the patient. In another embodiment, the method comprises determining the level of MPO mass in a bodily sample obtained from the patient. In another embodiment, the method comprises determining the level of one or more select MPO-generated oxidation products in a bodily sample obtained from the patient. The select MPO-generated oxidation products are dityrosine, nitrotyrosine, chlorotyrosine, methionine sulphoxide or an MPO-generated lipid peroxidation product.
    Type: Grant
    Filed: November 5, 2008
    Date of Patent: January 8, 2013
    Assignee: The Cleveland Clinic Foundation
    Inventors: Stanley L. Hazen, Marc S. Penn, Renliang Zhang
  • Patent number: 8352116
    Abstract: A tilt or acceleration sensing apparatus and method that allows a tilt or acceleration sensing device of a vehicle to determine: 1) a maximum fall angle of the vehicle, regardless of the orientation of the vehicle and the vehicle's tilt sensor(s) to the incline; or 2) the downward acceleration of the vehicle. In one embodiment, a method of determining a maximum fall angle of a vehicle includes sensing tilt angles of two sensing axes of the vehicle relative to a horizontal reference plane and calculating the maximum fall angle of the vehicle based on the tilt angles. The apparatus and method may also include comparing the maximum fall angle to predetermined values and generating output signals when the maximum fall angle exceeds the predetermined values. In another embodiment, a method of determining when a vehicle is sliding downhill includes sensing the accelerations of three sensing axes.
    Type: Grant
    Filed: January 13, 2010
    Date of Patent: January 8, 2013
    Assignee: Delta Systems, Inc.
    Inventors: Clifford H. Boylston, Arthur James Harvey, Nicholas Schragal
  • Patent number: 8346518
    Abstract: Systems and methods are provided for predicting the results of a therapeutic intervention to an eye. An imaging system is configured to provide image data representing at least a portion of the eye of the patient. An input device is configured to permit a user to design a proposed therapeutic intervention for the eye of the patient. A finite element modeling component is configured to generate a finite element model representing the condition of the eye of the patient after the proposed therapeutic intervention according to the image data, the proposed therapeutic intervention, and at least one biomechanical property of tissue comprising the eye. The generated model is constructed as to have no a priori restraints on the motion of the corneal limbus. A display is configured to display the generated model to the user.
    Type: Grant
    Filed: April 23, 2009
    Date of Patent: January 1, 2013
    Assignee: The Cleveland Clinic Foundation
    Inventors: William J. Dupps, Jr., Abhijit Sinha Roy
  • Patent number: 8345677
    Abstract: Rather than utilizing fixed point-to-point remapping of PIDS, the present invention utilizes the type of stream that the PIDS are associated with and the related program services IDs to specify the associations between input and output programs. This permits mapping at the program level and, therefore, allows dynamic responses to input program changes based upon the program mapping references. Resolving PID mapping based upon programs and the included services allows output PIDs to remain constant service-by-service even as the input programs change.
    Type: Grant
    Filed: May 12, 2005
    Date of Patent: January 1, 2013
    Inventors: Brian Crookes, Karl Stoll
  • Patent number: 8344934
    Abstract: One embodiment of the invention includes a synthetic aperture radar (SAR) system including a receiver configured to receive a plurality of reflected radar pulses corresponding to a plurality of radar transmission pulses having been reflected from a target region. A processing controller divides the target region into a plurality of tiles at a highest data layer and each of the plurality of tiles into a plurality of sub-tiles corresponding to one of a plurality of data layers and iteratively processes a portion of pulse data corresponding to a given tile associated with a higher data layer to generate pulse data corresponding to a given sub-tile in a lower data layer. An image processor is configured to generate a radar image of the target region based on the pulse data corresponding to each of the plurality of sub-tiles associated with a lowest data layer of the plurality of data layers.
    Type: Grant
    Filed: October 27, 2010
    Date of Patent: January 1, 2013
    Assignee: Northrop Grumman Systems Corporation
    Inventor: Robert Ryland
  • Patent number: 8346466
    Abstract: Systems and methods for determining heading of a traveling vehicle are provided. The systems and methods employ an image system to capture and match multiple distinctive features of an image area at a first and second point in time and to determine unit-vectors associated with the multiple distinctive features. A global positioning system (GPS) provides a translation vector for the first and second point and time and a coupled processor employs the unit-vectors and the translation vector to provide a corrected heading.
    Type: Grant
    Filed: November 11, 2009
    Date of Patent: January 1, 2013
    Assignee: Northrop Grumman Guidance & Electronics
    Inventors: Kainan Chueh, T Jeffrey Dickman, Reza Ahmadi
  • Patent number: 8345134
    Abstract: An Indium Tin Oxide (ITO) gate charge coupled device (CCD) is provided. The CCD device comprises a CCD structure having a substrate layer, an oxide layer over the substrate layer, a nitride layer over the oxide layer and a plurality of parallel ITO gates extending over the nitride layer. The CCD device further comprises a plurality of substantially similarly sized channel stop regions in the substrate layer that extend transversely relative to the ITO gates, such that a given pair of channel stop regions defining a pixel column of the CCD structure. The CCD device also comprises a plurality of vent openings that extend through the nitride layer along the plurality of substantially similarly sized channel stop regions to allow for penetration of hydrogen to at least one of the oxide layer and the substrate layer.
    Type: Grant
    Filed: April 13, 2010
    Date of Patent: January 1, 2013
    Assignee: Northrop Grumman Systems Corporation
    Inventors: Joseph T. Smith, Bron R. Frias, Paul A. Tittel, Robert R. Shiskowski, Nathan Bluzer
  • Patent number: 8345796
    Abstract: A communication system and method is provided that modifies a signal for transmission at a transmitter to reduce peaks associated with the signal. The signal can be modified employing signal shaping, signal clipping, signal decomposition or other techniques to remove peaks associated with the signal. The communication system can also correct the modified signal at a receiver to reconstruct the originally wanted signal.
    Type: Grant
    Filed: June 8, 2009
    Date of Patent: January 1, 2013
    Assignee: Northrop Grumman Systems Corporation
    Inventors: Ian Robinson, Frank Winter
  • Patent number: 8345920
    Abstract: One embodiment of the invention includes a gesture recognition interface system. The interface system may comprise at least one light source positioned to illuminate a first side of a light-diffusive screen. The interface system may also comprise at least one camera positioned on a second side of the light-diffusive screen, the second side being opposite the first side, and configured to receive a plurality of images based on a brightness contrast difference between the light-diffusive screen and an input object. The interface system may further comprise a controller configured to determine a given input gesture based on changes in relative locations of the input object in the plurality of images. The controller may further be configured to initiate a device input associated with the given input gesture.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: January 1, 2013
    Assignee: Northrop Grumman Systems Corporation
    Inventors: Bran Ferren, H. Keith Nishihara
  • Patent number: 8344116
    Abstract: A complex includes a nucleic acid and a cationic polymer with at least one side chain coupled to the nucleic acid. The at least one side chain including an acid degradable amine-bearing ketal or acetal linkage.
    Type: Grant
    Filed: March 17, 2009
    Date of Patent: January 1, 2013
    Assignee: Case Western Reserve University
    Inventor: Young Jik Kwon
  • Patent number: 8343228
    Abstract: An arthroplastic implant is for a basilar joint of a hand of a patient. The arthroplastic implant may include a body having a distal surface and a proximal surface opposite therefrom with the distal surface to be positioned adjacent a first metacarpal bone at the basilar joint of the hand of the patient. The arthroplastic implant may also include an anchor peg extending outwardly from the body to anchor the body within the basilar joint of the hand of the patient.
    Type: Grant
    Filed: September 3, 2008
    Date of Patent: January 1, 2013
    Assignee: The Cleveland Clinic Foundation
    Inventor: Thomas James Graham
  • Patent number: 8338394
    Abstract: A pharmaceutical composition for treating a metabolic disease in a mammalian subject includes a therapeutically effective amount of all-trans-13,14-dihydroretinoid, all-trans-13,14-dihydroretinoid derivative, or agent capable of modulating the level of at least one all-trans-13,14-dihydroretinoid or all-trans-13,14-dihydroretinoid derivative in the subject.
    Type: Grant
    Filed: October 9, 2007
    Date of Patent: December 25, 2012
    Assignee: Case Western Reserve University
    Inventors: Krzysztof Palczewski, Radu A. Moise
  • Patent number: 8338774
    Abstract: An optical sensor has an optical plate which is adapted to make surface contact on a pane, in particular a windshield of a motor vehicle. It further has one or preferably a plurality of photoreceivers arranged on the side of the optical plate facing away from the pane. An optical mask is arranged in the optical path upstream of each photoreceiver, the optical mask having light-blocking and light-transmissive surface areas. The light-transmissive surface areas each allow an optical path to traverse the optical plate, impinging on the photoreceiver and is delimited by the light-blocking surface areas.
    Type: Grant
    Filed: June 22, 2009
    Date of Patent: December 25, 2012
    Assignee: TRW Automotive Electronics & Components GmbH
    Inventor: Ulrich Backes
  • Patent number: 8338110
    Abstract: Provided herein methods for determining whether a subject, particularly a human subject, is at risk of developing, having, or experiencing a complication of cardiovascular disease, and methods of treating subjects who are identified by the current methods of being at risk for cardiovascular disease. In one embodiment, the method comprises determining levels of one or more oxidized apolipoprotein A-I related biomolecules in a bodily sample from the subject. Also, provided are kits and reagents for use in the present methods. Also provided are methods for monitoring the status of cardiovascular disease in a subject or the effects of therapeutic agents on subjects with cardiovascular disease. Such method comprising determining levels of one or more oxidized apolipoprotein A-I related molecules in bodily samples taken from the subject over time or before and after therapy.
    Type: Grant
    Filed: March 23, 2010
    Date of Patent: December 25, 2012
    Assignee: The Cleveland Clinic Foundation
    Inventors: Stanley L. Hazen, Michael Kinter, Marc S. Penn, Jonathan Smith, Lemin Zheng
  • Patent number: 8338720
    Abstract: An enclosure is provided for a vehicle. The enclosure comprises (a) a housing and (b) a cover for the housing. At least one of the housing and the cover includes a mounting portion for attaching the at least one of the housing and the cover to a vehicle and a compliant portion connected to the mounting portion. The compliant portion is plastically deformable.
    Type: Grant
    Filed: October 8, 2009
    Date of Patent: December 25, 2012
    Assignee: TRW Automotive U.S. LLC
    Inventors: Anthony Burgi, Mike Blossfeld
  • Patent number: 8339453
    Abstract: An apparatus for use in association with a vehicle having a windshield (38) includes a module (30) having an end portion which pivotally engages a bracket (40) connected with the windshield. The module (30) is pivotal relative to the bracket (40) to press a rain sensor coupler (34) connected with the module against the windshield (38) with a predetermined force. A camera assembly (72) may be disposed in the module (30). The camera assembly (72) may include an image sensor (154) and a camera lens (150). A polarizer lens (202) is disposed adjacent to the camera lens (150).
    Type: Grant
    Filed: July 14, 2010
    Date of Patent: December 25, 2012
    Assignee: TRW Automotive U.S. LLC
    Inventors: Thomas E. Blake, III, Robert J. Newton
  • Patent number: 8333584
    Abstract: A fuel-fired appliance is shut down when a predicted steady state combustion chamber temperature is below a known threshold. The predicted steady state temperature is based on combustion chamber temperatures during heat up of the burner and appliance.
    Type: Grant
    Filed: May 31, 2006
    Date of Patent: December 18, 2012
    Assignee: Beckett Gas, Inc.
    Inventor: Richard D. Cook
  • Patent number: 8329019
    Abstract: A zinc electroplating bath includes zinc ions and a brightening agent. The brightening agent is a polyamine or a mixture of polyamines that include a quaternary ammonium group.
    Type: Grant
    Filed: February 28, 2011
    Date of Patent: December 11, 2012
    Assignee: Coventya, Inc.
    Inventors: William E. Eckles, Thorsten Kuehler
  • Patent number: 8331682
    Abstract: Systems and methods are provided for recognizing a single stroke gesture. An input trajectory representing the single stroke gesture is received. The input trajectory is normalized to produce a normalized trajectory having a standard set of dimensions. The normalized trajectory is reduced to a standard number of substantially evenly spaced points. Respective covariance adjusted distances are determined for each class as the covariance adjusted position between a set of points representing each single stroke character classes and the substantially evenly spaced points representing the normalized trajectory.
    Type: Grant
    Filed: August 27, 2008
    Date of Patent: December 11, 2012
    Assignee: Northrop Grumman Systems Corporation
    Inventor: Adrian Kaehler
  • Patent number: D673754
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: January 1, 2013
    Assignee: Axios Mobile Assets
    Inventors: Richard MacDonald, John Psihos, Matthew Didio, Marc Topacio