Abstract: The present invention is directed towards monitoring and adjusting a power level of reverse subcarrier signals at an input of an optical node as opposed to at an input of a CMTS blade. Advantageously, reverse subcarrier signals are digitally transmitted throughout the optical link thereby avoiding the use of attenuators in the optical link. Therefore, any attenuation of the power level of the reverse subcarrier signals is caused by an RF feeder portion of the communications system. The CMTS blade then detects the power level of the reverse subcarrier signal that is equivalent to the power level at the input of an optical node and sends a control signal to CPE adjusting the transmitter power level without affecting the optical node dynamic range.

Abstract: The present invention is directed generally to reduction or inactivation of gene function or gene expression in cells in vitro and in multicellular organisms. The invention encompasses methods for mutating cells using a combination of mutagens, particularly wherein at least one mutagen is an insertional mutagen, to achieve homozygous gene mutation or mutation of multiple genes required cumulatively to achieve a phenotype to create knock-outs, knock-downs, and other modifications in the same cell. The invention is also directed to cells (and libraries thereof) and organisms created by the methods of the invention, including those in which at least one of the genes created by insertional mutagenesis is tagged by means of the insertion sequences thereby allowing identification of the mutated gene(s). The invention is also directed to libraries of mutated cells and their uses.

Abstract: In one embodiment, the disclosure relates to a method and apparatus for controlling the energy state of a qubit by bringing the qubit into and out of resonance by coupling the qubit to a flux quantum logic gate. The qubit can be in resonance with a pump signal, with another qubit or with some quantum logic gate. In another embodiment, the disclosure relates to a method for controlling a qubit with RSFQ logic or through the interface between RSFQ and the qubit.

Abstract: A system maintains communication between a plurality of unmanned vehicles within an environment. The system includes a sensor component and an evaluator. The sensor component senses objects within the environment. The sensor component is located on a first unmanned vehicle. The evaluator evaluates data from the sensor component. The evaluator is located on the first unmanned vehicle. The evaluator compares data for the first unmanned vehicle and a second unmanned vehicle and determines whether a trajectory of one of the first and second unmanned vehicles may be modified to maintain communication between the first unmanned vehicle and the second unmanned vehicle.

Abstract: Method and Apparatus for delivering audio signals from a source node to a destination node on a network. The apparatus uses a number of switches that transmit prioritized data on a packet network. The switches are coupled to a number of send/receive nodes for sending and receiving digital audio signals on the data network. The audio packet size and the receive buffers are sized to store a minimum possible number of audio samples to minimize latency in processing audio signals arriving at said receive node, but still ensure audio delivery without interruption due to packet data network delay. An additional feature of the invention is recovery of clock synchronization over the same data network by novel arrangement of transmission of timing packets on the network.

Abstract: A method of treating diabetic neuropathy in a subject includes administering to a subject having diabetes or at risk of diabetes a therapeutically effective amount of a pharmaceutical composition comprising at least one of sulfasalazine or a composition including 5-aminosalicyclic acid and sulfapyridine.

Abstract: A sensor probe suited for implanting into the skin of a person includes a sensor body which may be formed from a polymer which includes 2-hydroxyethyl methacrylate (HEMA). A sensing system is supported by the body. The sensing system exhibits a detectable change when the probe is exposed to the analyte in the fluid. The sensing system may include an enzyme capable of catalyzing a reaction of the analyte to form a reaction product and a dye system which absorbs in the infrared region of the spectrum in response to the reaction product.

Abstract: A bearing mounted ball valve (10) comprises a housing (12) having a throughbore and a valve seat (16) and an apertured ball (18) mounted within the housing in continuous engagement with the valve seat. The apertured ball is rotatable by rotation means (20), about an axis of rotation, between a throughbore open position and a throughbore closed position. The bearing mounted ball valve further comprises bearing means (26) coupled between the apertured ball and the housing for constraining the rotation of the apertured ball about the axis of rotation between the throughbore open and the throughbore closed position. In the throughbore closed position, the bearing means is adapted to release the apertured ball from the axis of rotation to permit the apertured ball to float into a sealing engagement with the valve seat.

Abstract: A pipet tip handling apparatus comprises a deep well plate that has a plurality of wells. Each of a first plurality of pipet tips has a head portion and a shank portion. A first tray is seated on the deep well plate and has openings for receiving the first pipet tips. The shank portions of the first pipet tips extend through the openings in the first tray and into the wells of the deep well plate. Each of a second plurality of pipet tips has a head portion and a shank portion. A second tray includes openings for receiving the second pipet tips. The shank portions of the second pipet tips extend through the openings of the second tray and into the head portions of the first pipet tips. The head portions of the first pipet tips support the second tray.

Abstract: Multiplexing of information from a plurality of information flows into fixed-length packets such as, but not limited to, MPEG packets allows efficient utilization of bandwidth and also can be used to reduce transmission latency. In addition, utilizing MPEG packets and transport streams for octet multiplexing allows the packets carrying octet-multiplexed data to easily be integrated with other MPEG packets for other services that are commonly found in cable transmission networks of all coax, hybrid fiber coax, and/or all fiber. The multiplexing/demultiplexing of octets using MPEG packets generally is described by mappings that specify the use of octets in MPEG packets. Changes to allocations in a map generally should be propagated in a way that reliably ensures that both the transmitter and receiver have a consistent view of the octet mappings.

Abstract: It has been determined that gamma sterilization of biodegradable polymer stents does not cause significant polymer cross-linking and collapse. Using sufficient spacing can lead to stents that display little if any detrimental effects from the procedure. In certain embodiments, using structures in the general region of about 100 micron spacing between the struts leads to highly functional stents that do not fuse. Further, the resulting stent has radially homogenous mechanical properties. Therefore, the stent has a uniform expansion within the lumen.

Abstract: A belt retractor for a vehicle safety belt has a frame, a belt spool for the safety belt which is rotatably arranged in the frame, a locking disc which is arranged on the belt spool and is connected therewith through an energy absorption element, and a blocking mechanism which allows to block the locking disc against a rotation in the unwinding direction of the safety belt in the frame. A detent is provided which is movably arranged in the belt spool and can prevent a rotation of the locking disc relative to the belt spool as a function of its position.

Abstract: One embodiment of the present invention includes a system for determining authenticity of substances. The system comprises a plurality of RF sensors distributed in a predefined location pattern relative to a location for placing a substance under analysis. Each of the RF sensors is configured to transmit a response to an interrogation signal with a unique identifier. The system also comprises an RF transmitter that transmits sequences of interrogation signals over different frequency bands at one or more power levels and an RF receiver that receives responses to the sequences of interrogation signals transmitted from the RF sensors. The system further comprises a response pattern analyzer that determines response patterns for the RF sensors to the interrogation sequences and transmits a difference indicator if at least one of the determined response patterns varies from as predetermined signature of an authentic substance.

Abstract: An air bag module (10) comprises an air bag (12), an inflator (14) and a gas distributing member (16) for distributing the gas escaping from the inflator (14) into different directions of flow. The gas distributing member (16) is configured so that it is deformed by the pressure exerted by the escaping gas such that thereby the distribution of the gas to the different directions of flow is influenced.

Abstract: A zinc electroplating bath includes zinc ions and a brightening agent. The brightening agent is a polyamine or a mixture of polyamines that include a quaternary ammonium group.

Abstract: One embodiment of the invention includes an atomic clock system including an alkali beam cell and an interrogation system configured to generate an optical pump beam and at least one optical probe beam that illuminate a detection chamber of the beam cell to pump evaporated alkali metal atoms. An optical detection system can provide a microwave signal to the detection chamber and can measure an intensity of the optical pump beam to determine a transition frequency corresponding to optimum photon absorption of the evaporated alkali metal atoms. A photodetection system can measure an intensity of the at least one optical probe beam and to generate an intensity signal that is provided to the optical detection system to substantially cancel Doppler broadening of the transition frequency resulting from non-orthogonal planar movement of the evaporated alkali metal atoms relative to the optical pump beam and the at least one optical probe beam.

Abstract: The present invention discloses the method of inhibiting complement activation mediated by factor B inhibitors, that involves: (a) inhibiting factor B binding to properdin-bound C3b; (b) inhibiting the release of Bb; (c) inhibiting the activation of neutrophils, monocytes, platelets, and endothelium; or (d) inhibiting/reducing the formation of PC3bBb, C3a, C5a, and MAC. The present invention also discloses the novel use of factor B inhibitors in the treatment of various immunological disorders, resulting either primarily from direct immune responses such as rheumatoid arthritis, anaphylactic shock, myasthenia gravis, asthma, Alzheimer's disease, and the like, or secondarily from clinical conditions such as cardiopulmonary bypass inflammation, vascular stenosis and restenosis, burn injury, and the like.

Abstract: An improved method and apparatus is used with a group of bales. The group of bales is gripped with a bale handling apparatus. A flexible strip is positioned around the group of bales. The group of bales is then moved while the group of bales is gripped by the bale handling apparatus and while the flexible strip extends around the group of bales. The flexible strip is positioned relative to the group of bales by a positioning member which is connected with the bale handling apparatus.

Abstract: Apparatus and method for providing a heated cleaning fluid to a vehicle surface. The apparatus has an inlet port for receiving an amount of fluid; an outlet port for dispensing an amount of heated fluid; a heating element that heats up fluid passing from the inlet to the outlet; and a control circuit for energizing at least a portion of the heating element with a voltage to heat the fluid passing from the inlet to the outlet. The apparatus also has expandable and compressible features and parts for protection against freezing.