Patents Represented by Attorney Ted J. Ebersole

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  • GLP-1 analog fusion proteins
    Patent number: 8273854
    Abstract: The invention provides specific GLP-1 analogs fused to specific IgG4-Fc derivatives. These fusion proteins have an increased half-life, decreased immunogenicity, and reduce effector activity. The fusion proteins are useful in treating diabetes, obesity, irritable bowel syndrome and other conditions that would be benefited by lowering plasma glucose, inhibiting gastric and/or intestinal motility and inhibiting gastric and/or intestinal emptying, or inhibiting food intake.
    Type: Grant
    Filed: October 31, 2008
    Date of Patent: September 25, 2012
    Assignee: Eli Lilly and Company
    Inventors: Wolfgang Glaesner, Rohn Lee Millican, Jr., Andrew Mark Vick