Patents Represented by Attorney, Agent or Law Firm Ted K. Ringsred
  • Medicinal aerosol formulations
    Patent number: 5681545
    Abstract: A self-propelling aerosol formulation which may be free from CFC's comprises a medicament, 1,1,1,2-tetrafluoroethane, a surface active agent and at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: October 28, 1997
    Assignee: Riker Laboratories, Inc.
    Inventors: Tarlochan S. Purewal, David J. Greenleaf
  • Medicinal aerosol formulations
    Patent number: 5674473
    Abstract: A self-propelling aerosol formulation which may be free from CFC's which comprises a medicament, 1,1,1,2-tetrafluoroethane, a surface active agent and at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: October 7, 1997
    Assignee: Riker Laboratories, Inc.
    Inventors: Tarlochan S. Purewal, David J. Greenleaf
  • Aerosol actuator having a linearly arranged canister receiving cavity, valve stem receptacle, orifice, and deagglomeration chamber
    Patent number: 5669376
    Abstract: An actuator for use in inhalation therapy comprising a nozzle .block having an orifice and at least one bleed hole, a deagglomeration chamber, and an exit chamber, together configured as a means for increasing the respirable fraction of an aerosol formulation. This invention also provides an actuator as described above in combination with an aerosol canister comprising a pharmaceutical formulation, and a method of administering a pharmaceutical formulation via inhalation therapy. The actuator finds particular use in improving the respirable fraction of drug in aerosol formulations. The actuator also retains non-respirable particles, thus reducing the amount of drug that is inadvertently administered orally.
    Type: Grant
    Filed: March 22, 1996
    Date of Patent: September 23, 1997
    Assignee: Minnesota Mining and Manufacturing Company
    Inventor: Constantinos Sioutas
  • Amplifier and method for sensing having a pre-bias or coupling step
    Patent number: 5663915
    Abstract: An improved current sensing differential amplifier which includes a separate p-channel bias stage to reduce the minimum operating voltage VCC of the circuit. The separate p-channel bias stage is also used to pre-bias a driver stage to more quickly generate differential output currents. Finally, the improved current sensing differential amplifier also includes negative feedback transistors to improve the recovery time of the circuit.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 2, 1997
    Assignees: United Memories, Inc., Nippon Steel Semiconductor Corporation
    Inventor: Kenneth J. Mobley
  • Dry powder inhalation device having deagglomeration/aerosolization structure responsive to patient inhalation
    Patent number: 5655523
    Abstract: An inhalation device for dry powder containing a chamber capable of receiving a dose of powdered medicament. The chamber is in communication with a patient port in the form of a mouthpiece or nasal adapter. The inhalation device also contains a deagglomeration/aerosolization apparatus capable of deagglomerating and/or aerosolizing a dose of powdered medicament and is operable by a patient-independent energy output source. The inhalation device further includes detection apparatus that ascertains patient inspiration through the patient port, and a control apparatus that actuates the deagglomeration/aerosolization apparatus in response to detection of patient inspiration.
    Type: Grant
    Filed: May 22, 1995
    Date of Patent: August 12, 1997
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Peter David Hodson, David Keith Smith, Anthony Charles Lammond Wass
  • Butixocort aerosol formulations in hydrofluorocarbon propellant
    Patent number: 5653961
    Abstract: Pharmaceutical solution aerosol formulations of butixocort propionate as the sole active drug agent and a propellant selected from the group consisting of 1,1,1,2-tetrafluoroethane, 1,1,1,2,3,3,3-heptafluoropropane, and a mixture thereof.
    Type: Grant
    Filed: March 31, 1995
    Date of Patent: August 5, 1997
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Rebecca A. McNally, Gary H. Ward
  • Fused cycloalkylimidazopyridines
    Patent number: 5648516
    Abstract: 6,7-propylene-, butylene-, or pentylene-bridged imidazopyridin-4-amines that induce interferon (.alpha.) biosynthesis in human cells, their pharmaceutical compositions containing such compounds and methods of inducing interferon (.alpha.) biosynthesis and treating viral infections involving the use of such compounds are disclosed.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: July 15, 1997
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Nick Nikolaides, John F. Gerster
  • Imidazo[4,5-c]pyridin-4-amine intermediates
    Patent number: 5644063
    Abstract: Imidazo[4,5-c]pyridin-4-amines that induce interferon (.alpha.) biosynthesis in human cells. Also disclosed are pharmaceutical compositions containing such compounds and methods of inducing interferon (.alpha.) biosynthesis involving the use of such compounds.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: July 1, 1997
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Kyle J. Lindstrom, Nick Nikolaides
  • Resolution transforming raster based imaging system and related transformation method
    Patent number: 5640191
    Abstract: Resolution transforming raster based imaging system where an image is formed by displaying dots arranged along scan lines, scanned by an energization beam, the scan lines having a predetermined resolution and the system is driven by an image bit map having rows with resolution multiple of said predetermined resolution, a subset of the rows being related to the scan lines, bits in rows unrelated to scan lines, and representative of dots to the displayed being displayed as dots offset to a next adjacent scan line and with a size related to the surrounding bit pattern.
    Type: Grant
    Filed: March 23, 1995
    Date of Patent: June 17, 1997
    Assignee: Bull HN Information Systems Italia S.p.A
    Inventors: Ferruccio Zulian, Aimone Zulian
  • Transmucosal delivery system
    Patent number: 5639469
    Abstract: A device for delivering a heparinic anticoagulant across a mucosal surface in order to achieve or maintain a therapeutically effective blood level of the heparinic anticoagulant. The device involves a matrix containing a therapeutically effective amount of a heparinic anticoagulant, and a mucoadhesive or other mechanism for maintaining the matrix in contact with the mucosal surface for a time sufficient to allow release of the heparinic anticoagulant to the mucosal surface.
    Type: Grant
    Filed: June 15, 1994
    Date of Patent: June 17, 1997
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Luce R. M. Benes, Francoise L. R. B. Horriere
  • Intermediate compounds of fused cycloalkylimidazopyridines
    Patent number: 5627281
    Abstract: 6,7-propylene-, butylene-, or pentylene-bridged imidazopyridin-4-amines and their intermediate compounds are described. Also disclosed are pharmaceutical compositions containing such compounds and methods of inducing interferon (.alpha.) biosynthesis and treating vital infections involving the use of such compounds.
    Type: Grant
    Filed: July 3, 1996
    Date of Patent: May 6, 1997
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Nick Nikolaides, John F. Gerster
  • Transdermal device for the delivery of alfuzosin
    Patent number: 5614210
    Abstract: A transdermal drug delivery device involving an acrylate or methacrylate based adhesive copolymer, a skin penetration enhancer, and a therapeutically effective amount of alfuzosin.
    Type: Grant
    Filed: March 31, 1995
    Date of Patent: March 25, 1997
    Assignee: Minnesota Mining and Manufacturing Company
    Inventor: Franz-Josef Braun
  • Process for the purification of inert gases
    Patent number: 5612011
    Abstract: Process for the purification of an inert gas recycled from a solid state polycondensation (SSP) reactor of aromatic polyester resins, comprising the step of adding the gas with oxygen or gas containing oxygen in stoichiometric quantity or in such an excess that the gas at the outlet of the catalytic bed contains no more than 250 ppm of oxygen, circulating the gas on a catalytic bed comprising Pt or Pt and Pd heated at temperatures from 250.degree. to 600.degree. C. and recycling the gas to SSP reactor with previous drying to eliminate the water formed in the oxidation stage.
    Type: Grant
    Filed: November 16, 1995
    Date of Patent: March 18, 1997
    Assignee: Sinco Engineering S.p.A.
    Inventors: Guido Ghisolfi, Dario Giordano, Giuseppina Boveri, Hussain A. K. Al Ghatta
  • Method of inhibiting leukotriene biosynthesis
    Patent number: 5612377
    Abstract: A method of inhibiting leukotriene biosynthesis, involving administering a compound of the formula: ##STR1## wherein M, R, R', R", and n are as defined herein. Also, a pharmaceutical composition involving such a compound and the use of such compounds in the manufacture of a pharmaceutical composition for inhibiting leukotriene biosynthesis.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: March 18, 1997
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Stephen L. Crooks, Bryon A. Merrill, Paul D. Wightman
  • 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
    Patent number: 5605899
    Abstract: 1-substituted, 2-substituted 1H-imidazo[4,5-c]-quinolin-4-amines are disclosed. These compounds function as antiviral agents, they induce biosynthesis of interferon, and they inhibit tumor formation in animal models. This invention also provides intermediates for preparing such compounds, pharmaceutical compositions containing such compounds, and pharmacological methods of using such compounds.
    Type: Grant
    Filed: December 12, 1994
    Date of Patent: February 25, 1997
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: John F. Gerster, Stephen L. Crooks, Kyle J. Lindstrom
  • Medicinal aerosol formulations
    Patent number: 5605674
    Abstract: A self-propelling aerosol formulation which may be free from CFC's which comprises a medicament, 1,1,1,2-tetrafluoroethane, a surface active agent and at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: February 25, 1997
    Assignee: Riker Laboratories, Inc.
    Inventors: Tarlochan S. Purewal, David J. Greenleaf
  • Process for 1H-imidazo[4,5-C]quinolines
    Patent number: 5602256
    Abstract: A process for the preparation of 1-substituted,4-substituted-1H-imidazo-[4,5-c]quinolines, intermediates in the preparation of such compounds, and processes for the preparation of such intermediates.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: February 11, 1997
    Assignee: Riker Laboratories, Inc.
    Inventors: Jean-Denis Andr e, Daniel Lagin
  • Sport boot with a fastening device to limit rearward swing or forward flex
    Patent number: 5590481
    Abstract: An article of sport footwear with a shell formed with two, respectively forward and rearward, longitudinally opposite openings which extend from a shell entrance and identify two lateral sides, with a bootleg pivoted on the shell and at least one fastening device bridging the corresponding opening and being adjustable in length, whose opposite ends are anchored on respective lateral sides of the shell proximate to the entrance to limit the rearward swing range of the bootleg and/or the forward flex of the boot.
    Type: Grant
    Filed: May 14, 1996
    Date of Patent: January 7, 1997
    Assignee: Dolomite S.p.A.
    Inventor: Franco Vaccari
  • Transdermal delivery device
    Patent number: 5585111
    Abstract: A transdermal drug delivery device involving a backing bearing at least one adhesive layer of an acrylate copolymer and a therapeutically effective amount of (S)-3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole. The device optionally further involves (i) a second adhesive layer of an acrylate copolymer and optionally a therapeutically effective amount of (S)-3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole, and (ii) a membrane intermediate the first and second adhesive layers.
    Type: Grant
    Filed: November 21, 1995
    Date of Patent: December 17, 1996
    Assignee: Minnesota Mining and Manufacturing Company
    Inventor: Timothy A. Peterson
  • Process for 1H-imidazo[4,5-c]quinolines
    Patent number: 5578727
    Abstract: A process for the preparation of 1-substituted,4-substituted-1H-imidazo-[4,5-c]quinolines, intermediates in the preparation of such compounds, and processes for the preparation of such intermediates.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: November 26, 1996
    Assignee: Riker Laboratories, Inc.
    Inventors: Jean-Denis Andre, Daniel Lagain