Abstract: A pharmaceutical tablet adapted for accurate division of a dose of a drug into two or more smaller doses, which tablet has two or more segments.

Abstract: Accurate means of dosing with a compressed, segmented pharmaceutical tablet, and tablettes formed from said tablets, is disclosed.

Abstract: An immediate release compressed pharmaceutical tablet that has two or more segments and a top and a bottom and has a height that exceeds the width of the tablet. The height is measured vertically from the top to the bottom of the tablet while it is in the tablet die in which it is fully compressed, after compression has been completed. The width is measured as the greatest horizontal dimension of the tablet at a location halfway between the top and the bottom of the tablet, except that when the horizontal cross-section of the tablet is substantially rectangular, the width is defined by locating the two shorter sides of the perimeter of the horizontal cross-section, and measuring the length of a line that is at right angle to the shorter sides.

Abstract: Described is a compressed multiple layer pharmaceutical tablet that has a height that exceeds the width of the tablet. The height is measured vertically from the top to the bottom of the tablet while it is in the tablet die in which it is fully compressed, after compression has been completed. The width is measured as the greatest horizontal dimension of the tablet at a location halfway between the top and the bottom of the tablet, except that when the horizontal cross-section of the tablet is substantially rectangular, the width is defined by locating the two shorter sides of the perimeter of the horizontal cross-section, and measuring the length of a line that is at right angle to the shorter sides. The layers can form a segment or, preferably, more than one segment.

Abstract: Deeply scored pharmaceutical tablets are disclosed, along with pharmaceutical tablets with a score in a segment that adjoins a segment lacking a pharmacologically effective dose of any drug.

Abstract: Described herein is the synthesis of alkylated and semi-synthetic glycosaminoglycosan ethers, referred to herein as “SAGEs.” The synthesis of sulfated alkylated SAGEs is also described. The compounds described herein are useful in a number of applications including wound healing, drug delivery, and the treatment of a number of inflammatory diseases and skin disorders.

Abstract: Provided are pharmaceutical dosage forms within structures such as hollow capsules, gelcaps, or sachets, adapted to allow ingestion of a whole dose or a preferably predetermined fraction of said dose when desired.

Abstract: An immediate release compressed pharmaceutical tablet that has two or more segments and a top and a bottom and has a height that exceeds the width of the tablet. The height is measured vertically from the top to the bottom of the tablet while it is in the tablet die in which it is fully compressed, after compression has been completed. The width is measured as the greatest horizontal dimension of the tablet at a location halfway between the top and the bottom of the tablet, except that when the horizontal cross-section of the tablet is substantially rectangular, the width is defined by locating the two shorter sides of the perimeter of the horizontal cross-section, and measuring the length of a line that is at right angle to the shorter sides.

Abstract: An immediate release compressed pharmaceutical tablet that has two or more segments and a top and a bottom and has a height that exceeds the width of the tablet. The height is measured vertically from the top to the bottom of the tablet while it is in the tablet die in which it is fully compressed, after compression has been completed. The width is measured as the greatest horizontal dimension of the tablet at a location halfway between the top and the bottom of the tablet, except that when the horizontal cross-section of the tablet is substantially rectangular, the width is defined by locating the two shorter sides of the perimeter of the horizontal cross-section, and measuring the length of a line that is at right angle to the shorter sides.

Abstract: A method for receiving and collecting particulate matter from drilled or cut holes in a tablet on a turntable and transporting said particulate to a remote location is described.

Abstract: A mailing form constructed of a single ply of substrate material which is configured such that it can be folded to form a financial document, such as an accounts payable or payroll check and check voucher, and wherein the ply is further folded to form an outgoing mailer envelope in which the financial document is enclosed for mailing to a recipient.

Abstract: A pharmaceutical composition of omeprazole for oral administration is described which includes: (a) a tabletted core component containing a therapeutically effective amount of a acid-labile compound, e.g., substituted benzamidazole such as omeprazole, an optional surface active agent, a filler, a pharmaceutically acceptable alkaline agent, and a binder; and (b) a single layer of coating on said core which comprises a layer of an enteric coating agent.

Abstract: A pressure-seal or pressure-activated sealing means for a mailing form constructed of a single ply of substantially opaque or printable substrate material which is configured such that it can be folded to form a financial document, for example, an accounts payable or payroll check and check voucher, and wherein the ply is further folded to form an outgoing mailer envelope in which the financial document is enclosed for mailing to a recipient. The mailing form can also include a substantially transparent single ply of substrate material for providing a window area for viewing or scanning therethrough.

Abstract: Forms, such as mailing forms, constructed as a single sheet or multiple sheets of standard paper size, which are printable by a single pass through a standard non-impact printer are described. Certain variations of the forms can be configured to be extendible to provide additional surface area for the form exceeding standard paper size. The extendible form can be adapted for use with mailing forms such as multi-part collated unit sets. The forms can be useful for providing a Customs Declaration and Dispatch Note having each part thereof printable by a single pass through a non-impact printer.

Abstract: An optical device for reducing glare which can be attached to ordinary eyeglasses or adapted to be worn as a pair of glare-reducing eyeglasses. The device includes lenses which have both transparent and translucent areas. The lenses are independently adjustable for individualizing the position of the lenses and thereby individualizing the glare-reducing capacity of the device. During operation, the lenses can be positioned such that the wearers' pupils are in alignment with the transparent area.

Abstract: A mailing form, including an upper sheet of material adhesively fastened to a lower sheet, is configured for the printing of information on a single side during passage of the form through a non-impact printer. At a first end of the form, the upper and lower sheets are fastened together permanently, forming a pocket to be used as a return envelope. The portion of the upper sheet which extends away from this pocket is divided into an inner flap, on which information is printed, and an outer flap, which is temporarily fastened to the lower sheet in order to protect an adhesive pattern during the printing process. After the printing process, the outer flap is removed and discarded, the inner flap is folded along lines provided for folding, and the lower sheet is folded on itself to enclose the inner flap. As the adhesive pattern holds the lower sheet shut in this position, address and return address information printed on the inner flap is visible through apertures in the lower sheet, which forms an envelope.

Abstract: A multi-part form useful as a delivery confirmation form is described. The form has two plies releasably adhered together by having adhesive and adhesive-release material disposed on opposing faces of the plies. Separable sections of the form are formed by a perforation line made along the length of the form. A gap in adhesive release material along the perforation line in the bottom ply of the form is provided to form a substantially permanent bond between the plies.

Abstract: The present invention relates to novel methods for detecting and evaluating bladder cancer. The methods of the present invention are based on the discovery that normalized amounts of hyaluronic acid (HA) and hyaluronidase (HAase) are diagnostic markers for the detection of bladder cancer, evaluation of its grade, monitoring of the efficacy of its treatment, and tumor recurrence.

Abstract: A form for creating a postcard having printing on both sides includes a front sheet and a back sheet, which are laminated using a pressure sensitive adhesive on a back surface of the front sheet. A fold line extends across the front sheet, while a tear line underlying the fold line extends across the back sheet. A gap in the adhesive preferably extends along the fold line. On one side of the fold line opposite to the direction of the gap, the inner surface of the back sheet has a release coating restricting the adhesion of the adhesive layer. After printing on the front surface of the front sheet, the section of the back sheet having this release coating is removed and discarded, and the front sheet is folded along the fold line, thereby providing a document having printing on both sides and a thickness sufficient for a postcard.