Abstract: Described herein are alkylated and semi-synthetic glycosaminoglycosan ethers, referred to herein as “SAGEs.” The synthesis of sulfated and alkylated SAGEs is also described. The compounds described herein are useful in a number of applications including use for ocular or ophthalmic treatment.
Type:
Grant
Filed:
November 23, 2011
Date of Patent:
December 11, 2012
Assignee:
University of Utah Research Foundation
Inventors:
Glenn D. Prestwich, Jianxing Zhang, Thomas P. Kennedy, Narayanam V. Rao
Abstract: A drug-containing pharmaceutical tablet adapted for accurate breaking which has two or more segments with at least one segment containing a drug.
Abstract: A method for the treatment of systemic arterial hypertension, which is based on the oral administration to a patient suffering from systemic arterial hypertension either in an amount of chlorthalidone of 2.5-10 mg daily, alone or in novel combination use with another anti-hypertensive.agent.