Patents Represented by Attorney Teresa J. Schultz

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  • Use of cyclodextrins as an active ingredient for treating dry AMD and solubilizing drusen
    Patent number: 8158609
    Abstract: The present invention is directed to the treatment of disorders involving the accumulation of drusen, such as dry age-related macular degeneration and geographic atrophy via administration of therapeutically effective amounts of at least one monomeric or polymeric cyclodextrin.
    Type: Grant
    Filed: November 2, 2007
    Date of Patent: April 17, 2012
    Assignee: Novartis AG
    Inventors: David Allen Marsh, Robert J. Collier, Jr., Michael A. Kapin, Youqin Tian, Eliot Mark Slovin
  • Methods of using zinc containing compounds to improve ocular health
    Patent number: 7981858
    Abstract: The present invention provides zinc complexes for use in methods of providing zinc to subjects in need of treatment. The invention further provides improved dietary supplement formulations for improving and maintaining ocular nutrition. In particular, the improved dietary supplement formulations comprise the zinc complexes described herein, antioxidant vitamins, minerals and excipients.
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: July 19, 2011
    Assignee: Alcon, Inc.
    Inventor: John C. Lang
  • Composition and methods for inhibiting the progression macular degeneration and promoting healthy vision
    Patent number: 7842722
    Abstract: The present invention provides improved dietary supplements and methods for inhibiting the progression of macular degeneration and promoting healthy vision. The dietary supplements of the invention contain cobeadlets comprising vitamin E and carotenoids in the form of Vitamin A, lutein and/or zeaxanthing. The dietary supplements of the invention further contain Vitamin C, copper and zinc and may also contain such ingredients as rosemary, DHA, other vitamins and minerals.
    Type: Grant
    Filed: December 14, 2004
    Date of Patent: November 30, 2010
    Assignee: Alcon, Inc.
    Inventor: John C. Lang
  • Compounds with 5-HTactivity useful for treating disorders of the outer retina
    Patent number: 7763619
    Abstract: Compositions and methods for treating disorders of the outer retina with compounds with 5-HT1A agonist activity are disclosed.
    Type: Grant
    Filed: July 22, 2005
    Date of Patent: July 27, 2010
    Assignee: Alcon, Inc.
    Inventors: Robert J. Collier, Jr., Michael A. Kapin, Mark R. Hellberg, Thomas R. Dean
  • Method for treating glaucoma comprising administering ?-lipoic acid
    Patent number: 7718697
    Abstract: The present invention provides compositions and methods for treating glaucoma, ocular hypertension, and age-related macular degeneration. More specifically, the present invention describes the use of agents that down-regulate expression of tanis and/or p21Waf1/Cip1/Sd1 genes to treat such disorders of the eye.
    Type: Grant
    Filed: December 7, 2004
    Date of Patent: May 18, 2010
    Assignee: Alcon, Inc.
    Inventors: Colene D. Drace, Gary W. Williams, Curtis R. Kelly, Najam A. Sharif
  • Use of serum amyloid A gene in diagnosis and treatment of glaucoma and identification of anti-glaucoma agents
    Patent number: 7662389
    Abstract: The present invention provides compositions and methods for treating glaucoma, methods for diagnosing glaucoma, and methods for identifying agents which may be useful in the treatment of glaucoma. More specifically, the present invention describes the use of agents that modulate the expression of serum amyloid A.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: February 16, 2010
    Assignee: Alcon, Inc.
    Inventors: Abbot F. Clark, Wan-Heng Wang, Loretta Graves McNatt
  • Inhibitors of glycogen synthase kinase-3 (GSK-3) for treating glaucoma
    Patent number: 7598288
    Abstract: The use of inhibitors of GSK-3 useful for treating glaucoma is disclosed.
    Type: Grant
    Filed: September 23, 2002
    Date of Patent: October 6, 2009
    Assignee: Alcon, Inc.
    Inventors: Mark R. Hellberg, Abbot F. Clark, Iok-Hou Pang, Peggy Elizabeth Hellberg, Loretta Graves McNatt, Wan-Heng Wang
  • Use of non-feminizing estrogens as treatment for retinal vascular diseases
    Patent number: 7488723
    Abstract: The invention provides pharmaceutical compositions containing non-feminizing estrogen and methods of using these compositions to prevent or ameliorate retinal vascular diseases.
    Type: Grant
    Filed: August 23, 2002
    Date of Patent: February 10, 2009
    Assignee: Alcon, Inc.
    Inventor: Iok-Hou Pang
  • Use of non-feminizing estrogens as retinoprotective agents for the treatment of glaucoma
    Patent number: 7384926
    Abstract: The invention provides pharmaceutical compositions containing non-feminizing estrogen and methods of using these compositions to prevent or ameliorate retinal and optic nerve damage associated with glaucoma.
    Type: Grant
    Filed: May 29, 2007
    Date of Patent: June 10, 2008
    Assignee: Alcon, Inc.
    Inventors: Iok-Hou Pang, Abbot F. Clark
  • Use of serum amyloid a gene in diagnosis and treatment of glaucoma and identification of anti-glaucoma agents
    Patent number: 7357931
    Abstract: The present invention provides compositions and methods for treating glaucoma, methods for diagnosing glaucoma, and methods for identifying agents which may be useful in the treatment of glaucoma. More specifically, the present invention describes the use of agents that modulate the expression of serum amyloid A.
    Type: Grant
    Filed: December 1, 2004
    Date of Patent: April 15, 2008
    Assignee: Alcon, Inc.
    Inventors: Abbot F. Clark, Wan-Heng Wang, Loretta McNatt
  • Composition and methods for inhibiting the progression macular degeneration and promoting healthy vision
    Patent number: 7267830
    Abstract: The present invention provides improved dietary supplements and methods for inhibiting the progression of macular degeneration and promoting healthy vision. The dietary supplements of the invention contain cobeadlets comprising vitamin E and carotenoids in the form of Vitamin A, lutein and/or zeaxanthing. The dietary supplements of the invention further contain Vitamin C, copper and zinc and may also contain such ingredients as rosemary, DHA, other vitamins and minerals.
    Type: Grant
    Filed: December 14, 2004
    Date of Patent: September 11, 2007
    Assignee: Alcon, Inc.
    Inventor: John C. Lang
  • Methods for diagnosing glaucoma and discovering anti-glaucoma drugs
    Patent number: 7220546
    Abstract: Methods for diagnosing glaucoma and for screening therapeutic agents for their usefulness in treating glaucoma are disclosed.
    Type: Grant
    Filed: September 10, 2003
    Date of Patent: May 22, 2007
    Assignees: Alcon Manufacturing, Ltd., University of North Texas Health Science Center
    Inventors: Abbot F. Clark, Robert J. Wordinger
  • Use of ?-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina
    Patent number: 7081482
    Abstract: The invention is directed to the use of ?-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina.
    Type: Grant
    Filed: November 29, 2000
    Date of Patent: July 25, 2006
    Assignee: Alcon, Inc.
    Inventors: Robert J. Collier, Jr., Louis Desantis, Jr., Michael A. Kapin
  • Use of AP-1 activators to treat glaucoma and ocular hypertension
    Patent number: 7005446
    Abstract: Compositions comprising AP-1 activators and methods of use for treating glaucoma and ocular hypertension are disclosed.
    Type: Grant
    Filed: April 7, 2000
    Date of Patent: February 28, 2006
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Debra L. Shade, Iok-Hou Pang, Abbot F. Clark
  • 6-hydroxy-indazole derivatives for treating glaucoma
    Patent number: 6956036
    Abstract: Substituted 1-(?-alkyl-ethylamino)-1H-indazol-6-ols useful for lowering and controlling IOP and treating glaucoma are disclosed
    Type: Grant
    Filed: November 14, 2000
    Date of Patent: October 18, 2005
    Assignee: Alcon, Inc.
    Inventors: Jesse A. May, Zixia Feng, Anura P. Dantanarayana
  • Use of neurotrophic factor stimulators for the treatment of ophthalmic neurodegenerative diseases
    Patent number: 6906077
    Abstract: Compositions and methods for the treatment of retina and optic nerve head neuropathy are disclosed. The compositions and methods are particularly directed to the use of neurotrophic factor stimulators, such as AIT-082 (neotrofin), in the treatment of glaucomatous neuropathy.
    Type: Grant
    Filed: December 1, 1999
    Date of Patent: June 14, 2005
    Assignee: Alcon Manufacturing, Ltd.
    Inventor: Iok-hou Pang
  • Stable carotene xanthophyll beadlet compositions and methods of use
    Patent number: 6716447
    Abstract: Beadlets comprising xanthophylls and carotenes and/or retinoids, dietary supplements comprising these beadlets and methods of use are disclosed.
    Type: Grant
    Filed: March 14, 2002
    Date of Patent: April 6, 2004
    Assignee: Alcon, Inc.
    Inventor: John C. Lang
  • Pyranoindazoles and their use for the treatment of glaucoma
    Patent number: 6696476
    Abstract: Pyranoindazoles are disclosed. Also disclosed are methods for the lowering and controlling of normal or elevated intraocular pressure as well as a method for the treatment of glaucoma using compositions containing one or more of the compounds of the present invention.
    Type: Grant
    Filed: December 11, 2002
    Date of Patent: February 24, 2004
    Assignee: Alcon, Inc.
    Inventors: Hwang-Hsing Chen, Jesse A. May, Bryon S. Severns
  • Serotonergic 5ht2 agonists for treating glaucoma
    Patent number: 6664286
    Abstract: Compounds with 5HT2 receptor agonist activity useful for treating glaucoma, including lowering intraocular pressure. Compositions and methods for their use are also disclosed.
    Type: Grant
    Filed: March 15, 2001
    Date of Patent: December 16, 2003
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Jesse A. May, Thomas R. Dean, Najam A. Sharif, Mark R. Hellberg
  • 2-acylaminobenzimidazole derivatives for treating glaucoma
    Patent number: 6660870
    Abstract: 2-Acylaminobenzimidazole deviates useful for treating glaucoma are disclosed.
    Type: Grant
    Filed: September 10, 2002
    Date of Patent: December 9, 2003
    Assignee: Alcon, Inc.
    Inventors: Andrew Ruskinko, Mark R. Hellberg, Namil Abdelmoula