Patents Represented by Attorney, Agent or Law Firm Testa, Hurwitz & Thibeault, LLP
  • Patent number: 7106296
    Abstract: An electronic book comprising multiple, electronically addressable, page displays is described. Said page displays may be formed on flexible, thin substrates. Said book may additionally encompass memory, power, control functions and communications.
    Type: Grant
    Filed: July 19, 1996
    Date of Patent: September 12, 2006
    Assignee: E Ink Corporation
    Inventor: Joseph M. Jacobson
  • Patent number: 7103401
    Abstract: A system and method for the in situ discrimination of healthy and diseased tissue. A fiberoptic based probe is employed to direct ultraviolet illumination onto a tissue specimen and to collect the fluorescent response radiation. The response radiation is observed at three selected wavelengths, about 403 nm, about 414 nm, and about 431 nm. The intensities of the 403 nm and 414 mn radiation are normalized using the 431 nm intensity. A score is determined using the ratios in a linear discriminant analysis (LDA). The tissue under examination is resected or not, based on the outcome of the LDA.
    Type: Grant
    Filed: July 10, 2002
    Date of Patent: September 5, 2006
    Assignee: MediSpectra, Inc.
    Inventors: Kevin T. Schomacker, Norman S. Nishioka, Alex R. Zelenchuk
  • Patent number: 7031651
    Abstract: Described are a system and method for facilitating private instruction over a network between a teacher and a student. Profile information is received from each student who registers for a private course. Each student who registers for a private course is included in a list of students who are unassigned to a teacher. Each teacher who is able to teach a private course has access over the network to the list of students and the profile information of the students. One of the teachers who is able to teach a given private course is assigned to one of the students in the list of students enrolled in that given private course based upon the profile information of that student.
    Type: Grant
    Filed: July 19, 2001
    Date of Patent: April 18, 2006
    Assignee: Englishtown, Inc.
    Inventors: Christopher McCormick, Alena Shtessel, Richard Sollom, Molly Lim
  • Patent number: 7031612
    Abstract: An optical transponder/transceiver for intermediate range (e.g., 10-50 km) optical communication applications utilizes an electroabsorption modulated laser for the transmitting device. Preferably, the laser operations at a wavelength of approximately 1310 nm and comprises an electroabsorption modulated Fabry-Perot laser.
    Type: Grant
    Filed: July 17, 2001
    Date of Patent: April 18, 2006
    Assignee: Multiplex, Inc.
    Inventors: Kang-Yih Liou, Tawee Tanbun-Ek, Won-Tien Tsang, Liang David Tzeng
  • Patent number: 7003558
    Abstract: A system for communicating according to a standard communication protocol for process control includes a plurality of interconnected computers. The system includes a module that permits communication of information between computers that communicate with process control equipment. The system also includes a module that permits a primary controlling machine to communicate with computers that communicate with process control equipment, and that permits a secondary controlling machine to take the place of the primary controlling machine when the primary controlling machine is unavailable. The system further includes a module that aggregates requests for information directed to one computer that communicates with a piece of process control equipment, communicates with the computer and obtains the information, and delivers the information to each of the requesters. The standard communication protocol for process control can be OPC, and the communicated information can be one or more process control parameters.
    Type: Grant
    Filed: October 15, 1999
    Date of Patent: February 21, 2006
    Assignee: Iconics, Inc.
    Inventors: Russell L. Agrusa, Jan Burian, Robert A. Braier
  • Patent number: 6994914
    Abstract: A water slurry process is used to prepare a prepreg and to manufacture articles from macrocyclic polyester oligomers. In one embodiment, a process for preparing a water suspension of macrocyclic polyester oligomers includes the steps of contacting a macrocyclic polyester oligomer and a polymerization catalyst with water and a surfactant, and mixing the macrocyclic polyester oligomer and polymerization catalyst with water and the surfactant thereby forming a suspension. In another embodiment, a process for impregnating macrocyclic polyester oligomers for polymerization includes the steps of providing a suspension of a macrocyclic polyester oligomer and a polymerization catalyst in water, applying the suspension to a base material, drying to remove water from the suspension, and pressing the dried suspension to a desired form. In yet another embodiment, a composition of macrocyclic polyester oligomer includes a macrocyclic polyester oligomer, a polymerization catalyst, and water.
    Type: Grant
    Filed: April 7, 2003
    Date of Patent: February 7, 2006
    Assignee: Cyclics Corporation
    Inventors: Steven J. Winckler, Tohru Takekoshi
  • Patent number: 6986942
    Abstract: There is disclosed a microwave absorbing structure which comprises a non-conductive matrix within which are embedded a plurality of spatially-separated ferro- or ferri-magnetic particles, each of which particles has a largest dimension no greater than 100 nm, said particles having been prepared by a process which includes a step in which the particles are formed within an organic macromolecular shell.
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: January 17, 2006
    Assignee: NanoMagnetics Limited
    Inventor: Eric Mayes
  • Patent number: 6982474
    Abstract: A semiconductor device and a method for fabricating a semiconductor device involve a semiconductor layer that includes a first material and a second material. The first and second materials can be silicon and germanium. A contact of the device has a portion proximal to the semiconductor layer and a portion distal to the semiconductor layer. The distal portion includes the first material and the second material. A metal layer formed adjacent to the relaxed semiconductor layer and adjacent to the distal portion of the contact is simultaneously reacted with the relaxed semiconductor layer and with the distal portion of the contact to provide metallic contact material.
    Type: Grant
    Filed: June 25, 2002
    Date of Patent: January 3, 2006
    Assignee: AmberWave Systems Corporation
    Inventors: Matthew T. Currie, Richard Hammond
  • Patent number: 6967490
    Abstract: An apparatus and method for the real-time, in-line testing of semiconductor wafers during the manufacturing process. In one embodiment the apparatus includes a probe assembly within a semiconductor wafer processing line. As each wafer passes adjacent the probe assembly, a source of modulated light, within the probe assembly, having a predetermined wavelength and frequency of modulation, impinges upon the wafer. A sensor in the probe assembly measures the surface photovoltage induced by the modulated light. A computer then uses the induced surface photovoltage to determine various electrical characteristics of the wafer.
    Type: Grant
    Filed: March 28, 2003
    Date of Patent: November 22, 2005
    Assignee: QC Solutions, Inc.
    Inventors: Emil Kamieniecki, Jerzy Ruzyllo
  • Patent number: 6967640
    Abstract: A mounted display assembly comprises a flexible substrate that supports both display elements and control circuits. The display assembly generally comprises: an electrical connection formed on the flexible substrate, the electrical connection having first and second contact pads; a display element in electrical communication with the first contact pad; and a control circuit mounted on the flexible substrate and in electrical communication with the second contact pad. In a preferred embodiment, the display element comprises a microencapsulated electrophoretic display medium. In another preferred embodiment, printing processes are employed in manufacturing methods for the display assembly.
    Type: Grant
    Filed: July 27, 2001
    Date of Patent: November 22, 2005
    Assignee: E Ink Corporation
    Inventors: Jonathan D. Albert, Holly G. Gates
  • Patent number: 6947844
    Abstract: The invention provides methods for producing high resolution crystals of ribosomes and ribosomal subunits as well as crystals produced by such methods. The invention also provides high resolution structures of ribosomal subunits either alone or in combination with protein synthesis inhibitors. The invention provides methods for identifying ribosome-related ligands and methods for designing ligands with specific ribosome-binding properties as well as ligands that may act as protein synthesis inhibitors. Thus, the methods and compositions of the invention may be used to produce ligands that are designed to specifically kill or inhibit the growth of any target organism.
    Type: Grant
    Filed: August 3, 2001
    Date of Patent: September 20, 2005
    Assignee: Yale University
    Inventors: Thomas A. Steitz, Peter B. Moore, Nenad Ban, Poul Nissen, Jeffrey Hansen
  • Patent number: 6947845
    Abstract: The invention provides methods for producing high resolution crystals of ribosomes and ribosomal subunits as well as crystals produced by such methods. The invention also provides high resolution structures of ribosomal subunits either alone or in combination with protein synthesis inhibitors. The invention provides methods for identifying ribosome-related ligands and methods for designing ligands with specific ribosome-binding properties as well as ligands that may act as protein synthesis inhibitors. Thus, the methods and compositions of the invention may be used to produce ligands that are designed to specifically kill or inhibit the growth of any target organism.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: September 20, 2005
    Assignees: Yale University, Rib-X Pharmaceuticals, Inc.
    Inventors: Thomas A. Steitz, Peter B. Moore, Joseph A. Ippolito, Nenad Ban, Poul Nissen, Jeffrey L. Hansen
  • Patent number: 6939361
    Abstract: An elongate guidewire for use with a free, unsecured, intervascular device having an elongate, enclosed, open ended channel for receiving the guidewire. The guidewire includes an elongate, flexible body having an outer dimension which is less than the inner dimension of the channel and an expandable and contractable stop member mounted on the guidewire body for movement between a first contracted position and a second expanded position. The expandable and contractable stop member is dimensioned in the first contracted position to move through said channel and in the second expanded position to preclude movement of said stop member through the channel.
    Type: Grant
    Filed: September 21, 2000
    Date of Patent: September 6, 2005
    Assignee: NMT Medical, Inc.
    Inventor: Stephen J. Kleshinski
  • Patent number: 6939848
    Abstract: The present invention provides methods for producing high resolution crystals of ribosomes and ribosomal subunits as well as the crystals produced by such methods. The x-ray diffraction patterns of the crystals provided by the present invention are of sufficiently high resolution for determining the three-dimensional structure of ribosomes and ribosomal subunits, for identifying ligand binding sites on ribosomes and ribosomal subunits, and for molecular modeling of ligands which interact with ribosomes and ribosomal subunits. The present invention provides methods for identifying ribosome-related ligands and methods for designing ligands with specific ribosome-binding properties. Thus, the methods of the present invention may be used to produce ligands which are designed to kill or inhibit any specific target organism(s).
    Type: Grant
    Filed: March 17, 2003
    Date of Patent: September 6, 2005
    Assignee: Yale University
    Inventors: Thomas A. Steitz, Peter B. Moore, Nenad Ban, Poul Nissen, Jeffrey Hansen
  • Patent number: 6940089
    Abstract: A method of fabricating a semiconductor structure. According to one aspect of the invention, on a first semiconductor substrate, a first compositionally graded Si1-xGex buffer is deposited where the Ge composition x is increasing from about zero to a value less than about 20%. Then a first etch-stop Si1-yGey layer is deposited where the Ge composition y is larger than about 20% so that the layer is an effective etch-stop. A second etch-stop layer of strained Si is then grown. The deposited layer is bonded to a second substrate. After that the first substrate is removed to release said first etch-stop Si1-yGey layer. The remaining structure is then removed in another step to release the second etch-stop layer. According to another aspect of the invention, a semiconductor structure is provided. The structure has a layer in which semiconductor devices are to be formed.
    Type: Grant
    Filed: April 4, 2002
    Date of Patent: September 6, 2005
    Assignee: Massachusetts Institute of Technology
    Inventors: Zhiyuan Cheng, Eugene A. Fitzgerald, Dimitri A. Antoniadis
  • Patent number: 6933822
    Abstract: A magnetically influenced current or voltage regulator includes a body of an anisotropic magnetisable material that provides a closed magnetic circuit. A first electrical conductor is wound around the body along at least a part of the close circuit for at least one turn which forms a first main winding. At least one second electrical conductor is wound around the body along at least a part of the closed circuit for at least one turn which forms a control winding. The winding axis for the main winding is at right angles to the winding axis for the control winding. Orthogonal magnetic fields are generated in the body when the first main winding and the control winding are excited. A characteristic of the anisotropic magnetisable material relative to a field in the main winding is controlled by means of a field in the control winding.
    Type: Grant
    Filed: October 24, 2002
    Date of Patent: August 23, 2005
    Assignee: Magtech AS
    Inventors: Espen Haugs, Frank Strand
  • Patent number: 6933154
    Abstract: The invention provides methods for determining a characteristic of a tissue sample, such as a state of health, using spectral data and/or images obtained within an optimal period of time following the application of a chemical agent to the tissue sample. The invention provides methods of determining such optimal windows of time. Similarly, the invention provides methods of determining other criteria for triggering the acquisition of an optical signal for classifying the state of health of a region of a tissue sample.
    Type: Grant
    Filed: November 15, 2002
    Date of Patent: August 23, 2005
    Assignee: MediSpectra, Inc.
    Inventors: Kevin T. Schomacker, Alex Zelenchuk, Ross Flewelling, Howard Kaufman
  • Patent number: 6934709
    Abstract: A distributed computer application can be made to communicate with a plurality of computer architectures. A first compiler compiles and converts input interface source code to produce a high level language including a plurality of computer architecture interfaces. A second compiler integrates application source code with the converted interface source code to produce the distributed computer application with the plurality of computer architecture interfaces that enable the distributed computer application to communicate with the plurality of computer architectures.
    Type: Grant
    Filed: June 8, 2001
    Date of Patent: August 23, 2005
    Assignee: MatrixOne, Inc.
    Inventor: David Tewksbary
  • Patent number: 6933518
    Abstract: Circuits for processing radio frequency (“RF”) and microwave signals are fabricated using field effect transistors (“FETs”) that have one or more strained channel layers disposed on one or more planarized substrate layers. FETs having such a configuration exhibit improved values for, for example, transconductance and noise figure. RF circuits such as, for example, voltage controlled oscillators (“VCOs”), low noise amplifiers (“LNAs”), and phase locked loops (“PLLs”) built using these FETs also exhibit enhanced performance.
    Type: Grant
    Filed: September 24, 2002
    Date of Patent: August 23, 2005
    Assignee: Amberwave Systems Corporation
    Inventors: Glyn Braithwaite, Richard Hammond, Matthew Currie
  • Patent number: 6919308
    Abstract: Disclosed are (1) osteogenic devices comprising a matrix containing substantially pure natural-sourced mammalian osteogenic protein; (2) DNA and amino acid sequences for novel polypeptide chains useful as subunits of dimeric osteogenic proteins; (3) vectors carrying sequences encoding these novel polypeptide chains and host cells transfected with these vectors; (4) methods of producing these polypeptide chains using recombinant DNA technology; (5) antibodies specific for these novel polypeptide chains; (6) osteogenic devices comprising these recombinantly produced proteins in association with an appropriate carrier matrix; and (7) methods of using the osteogenic devices to mimic the natural course of endochondral bone formation in mammals.
    Type: Grant
    Filed: December 17, 2002
    Date of Patent: July 19, 2005
    Assignee: Stryker Corporation
    Inventors: Hermann Oppermann, Engin Ozkaynak, Thangavel Kuberasampath, David C. Rueger, Roy H. L. Pang