Abstract: A directly-compressed, controlled release tablet contains N-acetyl cysteine as the active ingredient.

Abstract: The present invention pertains to a method for forming poly-acrylic acid granules and granules formed therefrom wherein the granules are flowable, have an increased bulk density relative to the as polymerized polyacrylic acids, and a low amount of dust which is generally characterized herein as particles which pass through a 325 mesh screen. The granules formed by the method of the present invention can be used to prepare controlled release tablets, especially controlled release pharmaceutical tablets. The controlled release properties of the tablets formed from granules prepared according to the present invention are unexpectedly better than tablets prepared from granules formed by other known granulation methods.

Abstract: A s,s′-bis-(&agr;,&agr;′-disubstituted-&agr;″-acetic acid)-trithiocarbonatte and derivatives thereof can be used as an initiator, chain transfer agent, or terminator for polymerization of monomers such as free radical polymerizable monomers. Homopolymers, copolymers, and the like as well as block copolymers can be made utilizing the trithio carbonate compound such as in a living free radical polymerization as well as to form telechelic polymers.

Abstract: Waterborne polyurethane dispersions are prepared by reacting (1) at least one polyisocyanate; (2) at least one active hydrogen containing compound, such as a polyol or a polyamide; and (3) preferably also at least one water-dispersability enhancing compound having water-dispersion enhancing groups, in order to form an isocyanate terminated prepolymer. The prepolymer subsequently is (1) optionally neutralized by reaction with at least one neutralizing agent, (2) dispersed in water, and then (3) chain extended by reaction with at least one of water, inorganic or organic polyamine having an average of about 2 or more primary and/or secondary amine groups, or combinations thereof. At least one plasticizer is introduced into the reaction mixture at any time during prepolymer formation or before the prepolymer is dispersed in water. The plasitcizer substantially or completely replaces other organic diluents or solvents. Various types of plasticizers may be employed, including reactive plasticizers.

Abstract: A polymer or copolymer composition derived from one or more unsaturated carboxylic acids that is cross-linked and carbamazepine in conjunction with conventional materials such as fillers, excipients, and surface active agents is disclosed. Solid dosage forms of immediate and sustained release tablets containing the polymer or copolymer composition can be formed by wet granulation or wet granulation followed by blending with direct compression ingredients. The polymer or copolymer, as a controlled release agent, can enhance controlled-release properties while meeting acceptable release rates as specified by the USP.

Abstract: The present invention relates to a halogen containing polymer compound containing a modified zeolite stabilizer. The modified zeolite stabilizer has a small particle diameter, narrow particle size distribution and less than 10 weight percent water. The modified zeolite stabilizer is formed by shock annealing, coating or a combination of the two methods.

Abstract: A process for polymerizing polycycloolefins containing pendant anhydride moieties is disclosed. The process utilizes a single component nickel containing catalyst of the formula EnNi(C6F5)2 wherein n is 1 or 2 and E represents a neutral electron donor ligand.

Abstract: Polymers comprising polycyclic repeating units containing pendant anhydride moieties are disclosed. The polymer can be polymerized from polycycloolefins containing pendant anhydride moieties in the presence of a nickel containing single component catalyst. In optional embodiments the polycycloolefin monomer containing the pendant anhydride functionality can be copolymerized with other polycycloolefin monomers that contain pendant functional groups to yield random copolymer products.

Abstract: A spatial puzzle game comprising a three dimensional array of transparent containers is disclosed. The containers are either fixed or movable relative to one another and each container has at least one hole it its surface. The movable containers are adapted for rotation about orthogonal axes. The holes of adjacent containers can be aligned by rotating the movable containers about their axes. Objects placed inside of the containers can be passed between containers when the holes of adjacent containers are aligned.

Abstract: This invention relates to A bioadhesive composition comprising two or more essentially excretable, essentially non-degradable polymer backbones, wherein the polymer backbones are crosslinked, said crosslink being degradable in a mammal, said cross-linked bioadhesive composition having an average bioadhesion factor showing bioadhesion equivalent to at least about 100 g s. The concept is to build a hydrogel that demonstrates bioadhesion to a mucosal surface that is crosslinked by a degradable linkage such as disulfide for use inside the body.

Abstract: A method for forming polyacrylic acid granules and granules prepared therefrom, wherein the granules are flowable, have comparable swelling characteristics and provide comparable tablet properties to powdered polyacrylic acid, have increased bulk density and contain minimal amounts of very small particles that can cause dusting and static adherence. The granules are used to prepare controlled-release tablets, especially for pharmaceutical purposes. The tablets prepared from granules obtained by the method of present invention have superior controlled release properties.

Abstract: An emulsion or suspension polymer comprising a vinyl chloride polymeric core and an acrylic ester-acrylonitrile polymeric shell is disclosed. The emulsion polymer is preferably prepared using a two-stage process. In the first stage, a vinyl chloride monomer is polymerized or copolymerized to form a first phase of a polymeric hard core having a relatively high chlorine content. In a second stage, the soft acrylic ester—acrylonitrile copolymer is made in situ in a reaction mixture comprising the first phase. The product provides both flame retardancy and low MFFT, and is useful in a variety of coating and binding applications.

Abstract: Disclosed are sunscreen compositions comprising zinc oxide and at least one of an effective amount of carbomer and an effective amount of C10 to C30 alkyl acrylate crosspolymers. The compositions most preferably utilize an oil in water emulsion. Also disclosed are related processes for producing and using such compositions.

Abstract: Methods for the addition polymerization of cycloolefins using a cationic Group 10 metal complex and a weakly coordinating anion of the formula: [(R′)zM(L′)x(L″)y]b[WCA]d wherein [(R′)zM(L′)x(L″)y] is a cation complex where M represents a Group 10 transition metal; R′ represents an anionic hydrocarbyl containing ligand; L′ represents a Group 15 neutral electron donor ligand; L″ represents a labile neutral electron donor ligand; x is 1 or 2; and y is 0, 1, 2, or 3; and z is 0 or 1, wherein the sum of x, y, and z is 4; and [WCA] represents a weakly coordinating counteranion complex; and b and d are numbers representing the number of times the cation complex and weakly coordinating counteranion complex are taken to balance the electronic charge on the overall catalyst complex.

Abstract: The present invention relates to cyclic polymers and their use in photolithographic applications. The cyclic polymers contain a pendant acid labile functional group and a functional group containing a protected hydroxyl moiety. The polymers are post modified by deprotecting the pendant hydroxyl moiety and reacting the deprotected hydroxyl containing moiety with a coreactant. The post-functionalized polymers find application in chemically amplified photoresist compositions.

Abstract: Polycyclic polymers containing pendant aromatic moieties are disclosed. The polymers exhibit light transparency properties to deep UV wave lengths making them useful for high resolution photolithographic applications. These polymers are particularly useful in chemically amplified positive and negative tone resists.

Abstract: Low molecular weight &agr;-methylstyrene oligomers are obtained by oligomerizing &agr;-methylstyrene in the presence of a single component initiator complex containing a cation component and a weakly coordinating anion component. The initiator complex is non-corrosive and does not have to be neutralized or removed from the obtained product.

Abstract: A rheology modifying copolymer composition containing a cross-linked copolymer of unsaturated carboxylic acid, a hydrophobic monomer, a hydrophobic chain transfer agent, a cross linking agent, and, optionally, a steric stabilizer, provides increased viscosity in aqueous electrolyte-containing environments.

Abstract: The invention is directed to polymers containing a repeating unit derived from a norbornene sulfonamide. These may be addition polymers which include copolymers with one or more comonomers such as norbornene, ethylene, an acrylate or sulfur dioxide or carbon monoxide. Said monomers may be polymerized using single or multicomponent Group VIII catalysts. The norbornene sulfonamides can also form ROMP polymers using known metathesis catalysts. Preferably the ROMP polymers may be hydrogenated to give more stable polymers.

Abstract: A block copolymer for hair styling compositions includes hydrophilic and hydrophobic blocks which allow for optimization of desirable characteristics of the hair styling composition, such as flow onto the hair, prevention of curl droop, style retention at high humidity, tack, hardness, resistance to flaking, restylability, volumizing, and washability from the hair. The copolymer includes a polyacrylate backbone of hydrophobic blocks, with hydrophilic acrylate side chains. The copolymer is suitable for the formulation of a number personal care, household, hair care, skin care and other formulation. The copolymer is suited to incorporation into low VOC hydro-alcoholic hair styling compositions to meet reduced VOC, regulations.